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NHLBI grants MU $8.47 million for research on cardiovascular diseases

One of the largest medical research grants ever awarded to the University of Missouri was announced today by MU scientists and administrators. The National Institutes of Health grant will help answer important questions about such prevalent health problems as high blood pressure, diabetes and stroke. The conditions are closely associated with cardiovascular disease, which is the leading cause of death in Missouri and the nation.

7 May 2010

Amira Pharmaceuticals' LPA1 receptor antagonist program data published in British Journal of Pharmacology

Amira Pharmaceuticals, Inc. announced today that preclinical data from its LPA1 receptor antagonist program has been published in the British Journal of Pharmacology.

7 May 2010

Pfizer presents data on in vivo activity of PF-04523655 siRNA drug candidate at ARVO annual meeting

Quark Pharmaceuticals, Inc., the world leader in clinical development of RNAi-based therapeutics, announced today that researchers from Pfizer, Inc. presented data on in vivo activity of PF-04523655 at the Association for Research in Vision and Ophthalmology (ARVO) annual meeting, being held May 2-6, 2010 in Fort Lauderdale.

7 May 2010

Swedish researchers present a new principle for inhibiting atherosclerosis

7 May 2010

Mouse study may lead to new therapies for Parkinson's disease

Endometrial stem cells injected into the brains of mice with a laboratory-induced form of Parkinson's disease appeared to take over the functioning of brain cells eradicated by the disease.

7 May 2010

Tel Aviv researchers develop microscope-based cell scanner to speed research into fat-busting drugs

Anglers rely on fish finders to help them locate the big catch. Now Tel Aviv University researchers in tissue engineering have developed a "fat finder" that can help scientists accelerate their research into new fat-melting drugs.

7 May 2010

Bioengineers define relationship between key regulatory proteins

With thousands of scientists across the globe searching for ways to use adult stem cells to fight disease, there's a growing emphasis on finding the "master regulators" that guide the differentiation of stem cells. New research from Rice University and the University of Cambridge suggests that a closely connected trio of regulatory proteins fulfills that role in hematopoietic stem cells (HSCs), the self-renewing cells the body uses to make new blood cells.

7 May 2010

Darwin may have lost his own children due to ill effects of inbreeding

Charles Darwin whose theories on evolution have been the basis of all that we know about the evolution of mankind and genetics may have lost his own progeny to inbreeding says a new study.

6 May 2010

Series Three of Percepta's Gene Expression Profiling Life Science Dashboard market research report

Percepta Associates Inc. announces the release of Series Three of its Gene Expression Profiling Life Science Dashboard market research report. Unique to the Percepta report, Series Three offers comparisons to the findings of Series One (February 2007) and Series Two (April 2008).

6 May 2010

Public need to be informed of nanotechnology's risks as well as benefits: Survey

A new national survey on public attitudes toward medical applications and physical enhancements that rely on nanotechnology shows that support for the technology increases when the public is informed of the technology's risks as well as its benefits - at least among those people who have heard of nanotechnology.

6 May 2010

Neuroscientists investigate alcohol dependency, withdrawal in C. elegans worms

Drinking alcohol over a long period of time profoundly affects the brain, which adapts to the intoxicant and causes withdrawal symptoms when consumption stops.

6 May 2010

Study aims to clarify expression patterns of CD24 in NSCLC

The May edition of the Journal of Thoracic Oncology features a study aimed to clarify expression patterns of a novel cancer biomarker, CD24, in non-small cell lung carcinomas (NSCLC) and to correlate the findings to clinicopathologic variables, such as performance status, age, gender and prognostic significance.

6 May 2010

Whole grain barley products with low glycemic response provide favourable metabolic benefits

Evidence from observational studies indicates that diets rich in whole grain reduce risk of obesity and other diseases related to the metabolic syndrome e.g. type 2 diabetes and cardio-vascular disease. The mechanisms involved are only partially elucidated. Work within HEALTHGRAIN has revealed novel insights regarding some potential mechanisms.

6 May 2010

Scientists analyze genetic networks of microRNAs in tumors

Genes interact in complex networks that govern cellular processes, much like people connect a social network through relationships. Researchers are now discovering how biological networks change and are rewired in cancer.

6 May 2010

Neuroscientist Snyder presents annual Ellis S. Grollman Lecture at UMB

If a drug was developed to block a key protein linked to the onset of Huntington's Disease, it could have a clear path to the part of the brain most affected by the disease, while not bothering other parts of the brain and body, said distinguished neuroscientist Solomon H. Snyder, MD, to an audience of about 300 students and faculty at the University of Maryland, Baltimore (UMB).

6 May 2010

Research reveals reason for ineffectiveness of antioxidants against cardiovascular disease

A new study by researchers at the Swedish medical university Karolinska Institutet shows that the immune defence's T cells can attack the "bad" LDL cholesterol and thereby cause an inflammation that leads to atherosclerosis. By producing a vaccine against the T cell receptors, the researchers have managed to inhibit the development of atherosclerosis in animals.

6 May 2010

ViaCyte granted three new U.S. patents

ViaCyte, Inc., a preclinical stage stem cell engineering company focused on diabetes, announced today that it has received three additional U.S. Patents.

6 May 2010

Multistage nanovector system for siRNA delivery lengthens therapeutic effects of ovarian cancer treatment

New research by scientists at The University of Texas Health Science Center at Houston (UTHealth) and The University of Texas M. D. Anderson Cancer Center could make it easier for patients to use a family of promising experimental cancer therapeutics known as small interfering RNA (siRNA).

6 May 2010

VEGF is key target for new anti-angiogenesis drugs, Spanish team reports

Analyzing the expression of particular genes in lung cancers could soon allow researchers to identify groups of patients who are likely to benefit most from treatment with angiogenesis-inhibitor drugs, a Spanish team reports.

6 May 2010

Research reveals role of ovarian hormone progesterone in alteration of breast stem cells

Cancer researchers at Princess Margaret Hospital (PMH) have discovered that the ovarian hormone progesterone plays a pivotal role in altering breast stem cells, a finding that has important implications for breast cancer risk.

6 May 2010

Medical Science News

NHLBI grants MU $8.47 million for research on cardiovascular diseases

Amira Pharmaceuticals' LPA1 receptor antagonist program data published in British Journal of Pharmacology

Pfizer presents data on in vivo activity of PF-04523655 siRNA drug candidate at ARVO annual meeting

Swedish researchers present a new principle for inhibiting atherosclerosis

Mouse study may lead to new therapies for Parkinson's disease

Tel Aviv researchers develop microscope-based cell scanner to speed research into fat-busting drugs

Bioengineers define relationship between key regulatory proteins

Darwin may have lost his own children due to ill effects of inbreeding

Series Three of Percepta's Gene Expression Profiling Life Science Dashboard market research report

Public need to be informed of nanotechnology's risks as well as benefits: Survey

Neuroscientists investigate alcohol dependency, withdrawal in C. elegans worms

Study aims to clarify expression patterns of CD24 in NSCLC

Whole grain barley products with low glycemic response provide favourable metabolic benefits

Scientists analyze genetic networks of microRNAs in tumors

Neuroscientist Snyder presents annual Ellis S. Grollman Lecture at UMB

Research reveals reason for ineffectiveness of antioxidants against cardiovascular disease

ViaCyte granted three new U.S. patents

Multistage nanovector system for siRNA delivery lengthens therapeutic effects of ovarian cancer treatment

VEGF is key target for new anti-angiogenesis drugs, Spanish team reports

Research reveals role of ovarian hormone progesterone in alteration of breast stem cells

How can microdialysis benefit drug development

Global and Local Efforts to Take Action Against Hepatitis

Addressing Important Cardiac Biology Questions with Shotgun Top-Down Proteomics

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