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Dorsolateral prefrontal cortex involved in cognitive aspects of ToM, says study

The ability to infer what another person is thinking is an essential tool for social interaction and is known by neuroscientists as "Theory of Mind" (ToM), but how does the brain actually allow us to do this? We are able to rationally infer what someone knows, thinks, or intends, but we are also able to "slip into their shoes" and infer how they feel, and it seems that the brain processes these different types of information in different ways, as confirmed by a new report in the June 2010 issue of Elsevier's Cortex.

5 May 2010

Quark to present poster on predicting risk of DGF following machine perfusion of renal transplants at ATC 2010

Quark Pharmaceuticals, Inc., the world leader in clinical development of RNAi-based therapeutics, announced today the presentation of a poster at the 2010 American Transplant Congress titled, "A Nomogram for Predicting Risk of Delayed Graft Function Following Machine Perfusion of Renal Transplants."

5 May 2010

Genetics researchers use new approach to detect causal gene variants

In findings that may speed the search for disease-causing genes, a new study challenges the prevailing view that common diseases are usually caused by common gene variants (mutations). Instead, say genetics researchers, the culprits may be numerous rare variants, located in DNA sequences farther away from the original "hot spots" than scientists have been accustomed to look.

5 May 2010

Scientists develop new web-based algorithm techniques to identify DNA sequences

Life is almost unbearably complex. Humans and mice, frogs and flies toggle genes on and off in dizzying combinations and sequences during their relentless march from embryo to death. Now scientists seeking to understand the machinations of the proteins behind the genomic wizard's screen have a powerful new tool at their disposal, courtesy of researchers at the Stanford University School of Medicine.

5 May 2010

FDA requested to publish data supporting assertion on HPV types 6, 11 causing vulvar, vaginal cancers

A Connecticut cancer pathologist/physician/scientist with extensive experience in the field for the past half century has formally challenged the FDA to back claims on its website that human papillomavirus (HPV) genotypes 6 and 11 cause vulvar and vaginal cancers in women.

5 May 2010

Palatin Technologies granted patent relating to small molecule compounds that bind to melanocortin receptors

Palatin Technologies, Inc. announced that the U.S. Patent and Trademark Office issued U.S. Patent No. 7,709,484, titled "Substituted Melanocortin Receptor-Specific Piperazine Compounds," today. The claims in the issued patent relate to small molecule compounds which bind to melanocortin receptors.

5 May 2010

Protein PEA-15 stops T-cell proliferation

New research has identified that a key protein called PEA-15 stops T-cell proliferation by blocking the cell's ability to reproduce. The control of T-cell proliferation is essential in preventing certain blood cancers and autoimmune diseases, as well as the orchestration of the immune response to infection. Findings of the study are reported in a recent online issue of The FASEB Journal, a publication of The Federation of American Societies for Experimental Biology.

5 May 2010

UK GTAC, MHRA approve Scancell's Phase I clinical trial of SCIB1 DNA ImmunoBody vaccine

Scancell Holdings Plc,, the developer of therapeutic cancer vaccines, today announced at BIO2010 in Chicago that its proposal to conduct a Phase I clinical trial on SCIB1, its DNA ImmunoBody® vaccine being developed for the treatment of melanoma, has been approved in the UK by the Gene Therapy Advisory Committee and by the Medicines and Healthcare products Regulatory Agency Medicines Division.

5 May 2010

Argos Therapeutics announces presentations on sCD83 protein capabilities at 2010 American Transplant Congress

Argos Therapeutics today announced two oral presentations detailing data on its soluble CD83 (sCD83) protein program at the 2010 American Transplant Congress, held May 1-5 in San Diego. The data, which were produced by Argos in collaboration with scientists from the University of Western Ontario, demonstrate that sCD83 is capable of inducing immune system tolerance to transplant grafts and suppressing an anti-donor antibody response, via a multi-faceted mechanism-of-action that impacts B and T cells, as well as dendritic cells.

5 May 2010

UVA exposure at early age does not cause melanoma

Early life exposure to ultraviolet A light does not cause melanoma in a fish model that previously made that connection, scientists from The University of Texas MD Anderson Cancer Center reported today in the online Early Edition of the Proceedings of the National Academy of Sciences.

5 May 2010

StemCells first-quarter total revenue up 307%

StemCells, Inc., a leading stem cell technology company with the dual focus of novel therapeutics and innovative research products, today reported financial results for the first quarter ended March 31, 2010 and recent business highlights.

5 May 2010

Physically active lifestyle during adolescence can reduce effect of mutation in FTO gene: Study

The FTO gene is obesity's main ally. Several studies are now attempting to reveal the factors that play a key role in fighting against it. A new study led by Spanish researchers shows that a physically active lifestyle during adolescence can reduce the effect of a mutation in this gene which predisposes someone to becoming overweight or obese.

5 May 2010

Study: Parvovirus therapy offers complete regression of malignant brain tumors

Particular parvoviruses normally infect rodents, but they are also infectious for human cells. However, they do not cause any disease symptoms in humans. Most importantly, these viruses have an astonishing property: They kill infected tumors cells without causing any damage to healthy tissue.

5 May 2010

High doses of antioxidant nutritional supplements may predispose cells to develop cancer

High doses of antioxidant nutritional supplements, such as vitamins C and E, can increase genetic abnormalities in cells, which may predispose supplement-takers to developing cancer, according to a new study from the Cedars-Sinai Heart Institute.

5 May 2010

Anavex reports promising results from ANAVEX 2-73 Alzheimer's disease compound in animal studies

Anavex Life Sciences Corp. is pleased to report promising results from animal studies with ANAVEX 2-73, the company's lead compound for the treatment and modification of Alzheimer's disease.

5 May 2010

Vitamin A does not improve maternal, infant health, study finds

Giving women vitamin A supplements does not reduce maternal death rates or improve the health of infants, according to a study published Tuesday in the Lancet, the New York Times reports.

5 May 2010

Animal study shows insulin prevents artery damage

Long suspected of worsening artery damage in patients with diabetes, insulin instead protects blood vessels, a new study by Joslin Diabetes Center scientists indicates.

5 May 2010

Study: Flaxseed diet reduces ovarian cancer, increases survival rates

In the race to find answers about ovarian cancer, researchers now have something to cluck about. For five years, University of Illinois researchers have been using the chicken as a model to study this deadly disease and have recently discovered that a diet enriched with flaxseed decreases severity of ovarian cancer and increases survival in hens.

5 May 2010

Mayo Clinic researchers identify genetic variants in serotonin genes that impact IBS

Most people associate serotonin with brain neurology, but over 95 percent of the body's serotonin occurs in the gastrointestinal tract, which has a complex neuronal circuit that has been called "the second brain" of the body.

5 May 2010

HPV test recommended for national cervical cancer screening programmes

Two studies suggest that testing for the human papillomavirus (HPV) - the major cause of cervical cancer - could be used in national cervical cancer screening programmes.

4 May 2010

Medical Science News

Dorsolateral prefrontal cortex involved in cognitive aspects of ToM, says study

Quark to present poster on predicting risk of DGF following machine perfusion of renal transplants at ATC 2010

Genetics researchers use new approach to detect causal gene variants

Scientists develop new web-based algorithm techniques to identify DNA sequences

FDA requested to publish data supporting assertion on HPV types 6, 11 causing vulvar, vaginal cancers

Palatin Technologies granted patent relating to small molecule compounds that bind to melanocortin receptors

Protein PEA-15 stops T-cell proliferation

UK GTAC, MHRA approve Scancell's Phase I clinical trial of SCIB1 DNA ImmunoBody vaccine

Argos Therapeutics announces presentations on sCD83 protein capabilities at 2010 American Transplant Congress

UVA exposure at early age does not cause melanoma

StemCells first-quarter total revenue up 307%

Physically active lifestyle during adolescence can reduce effect of mutation in FTO gene: Study

Study: Parvovirus therapy offers complete regression of malignant brain tumors

High doses of antioxidant nutritional supplements may predispose cells to develop cancer

Anavex reports promising results from ANAVEX 2-73 Alzheimer's disease compound in animal studies

Vitamin A does not improve maternal, infant health, study finds

Animal study shows insulin prevents artery damage

Study: Flaxseed diet reduces ovarian cancer, increases survival rates

Mayo Clinic researchers identify genetic variants in serotonin genes that impact IBS

HPV test recommended for national cervical cancer screening programmes

How can microdialysis benefit drug development

Global and Local Efforts to Take Action Against Hepatitis

Addressing Important Cardiac Biology Questions with Shotgun Top-Down Proteomics

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