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New England Biolabs to supply Wellcome Trust Sanger Institute next-generation sequencing library construction reagents

As an important supplier to the Wellcome Trust Sanger Institute, New England Biolabs is pleased to announce that the Sanger Institute will use New England Biolabs as one of its suppliers for next-generation sequencing library construction reagents.

From New England Biolabs 5 Feb 2010

Study suggests molecules and pathways in mood regulation and circadian rhythms are intertwined

Scientists at Emory University School of Medicine have discovered unexpected properties for a precursor to melatonin, the hormone that regulates sleep cycles.

5 Feb 2010

Access Pharmaceuticals initiates Cobalamin technology program for targeted delivery of siRNA therapies

ACCESS PHARMACEUTICALS, INC. announced today that it initiated an internal pre-licensing program to confirm the utility of its proprietary Cobalamin (vitamin B12) platform technology for targeted delivery of siRNA therapies. The program is considered important because, despite the widely publicized potential of RNA therapy, researchers up to now have been stymied in their efforts to design a pharmaceutical product that efficiently transports siRNA therapeutics into the cells they are designed to inhibit or kill.

5 Feb 2010

Researchers may have discovered how hormone progesterone prevents preterm birth

Researchers at Yale School of Medicine believe they may have discovered how the hormone progesterone acts to prevent preterm birth.

5 Feb 2010

International Stem Cell opens new cell production facility in Oceanside, California

International Stem Cell Corporation, www.internationalstemcell.com, announced today that its new cell production facility has passed final building inspection, which will enable development and manufacturing of the company and its partners’ clinical-grade stem cell products.

5 Feb 2010

New research reveals flying bats apply the laws of sonar physics to locate objects in the dark

The best way to track a moving object with a flashlight might be to aim it to one side, catching the object in the edge of the beam rather than the center. New research at the Weizmann Institute of Science reveals that bats, which 'see' with beams of sound waves, skew their beams off-center when they want to locate an object. The research, which recently appeared in Science, shows that this strategy is the most efficient for locating objects.

5 Feb 2010

New class of compound could become effective antidepressant with minimal side effects

Chemists at Oregon State University have discovered and synthesized a new compound that in laboratory and animal tests appears to be similar to, but may have advantages over one of the most important antidepressant medications in the world.

5 Feb 2010

iPSC technology for identifying agents that reprogram human somatic cells receives Notice of Allowance

Fate Therapeutics, Inc. received a Notice of Allowance from the United States Patent and Trademark Office for U.S. Patent Application Number 10/997,146 entitled "Methods for Reprogramming Somatic Cells." Upon issuance, the patent will cover foundational induced pluripotent stem cell (iPSC) technology for identifying agents that enable the reprogramming of human somatic cells, including pluripotency genes, small molecules and biologics.

5 Feb 2010

Prehistoric data suggests link between tooth enamel defects and early mortality

Ancient human teeth are telling secrets that may relate to modern-day health: Some stressful events that occurred early in development are linked to shorter life spans.

5 Feb 2010

Bioheart initiates REGEN Phase I Clinical Trial for testing genetically modified MyoCell in CHF patients

Bioheart, Inc., announced today that the company has commenced work on its REGEN trial, a Phase I Clinical Trial to test genetically modified MyoCell® in patients suffering from Congestive Heart Failure (CHF). Bioheart’s MyoCell® is a regenerative cell therapy that uses myoblasts, or muscle stem cells,that are grown from a patient’s own muscle. MyoCell® has been tested successfully on patients in four clinical trials.

5 Feb 2010

Research could help in developing more effective treatments for wound infections

Bacteria that infect chronic wounds can be deadly to maggot 'biosurgeons' used to treat the lesions, show researchers writing in the journal Microbiology. The findings could lead to more effective treatment of wounds and the development of novel antibiotics.

5 Feb 2010

Scientists discover new technique to destroy individual diseased cells

Using lasers and nanoparticles, scientists at Rice University have discovered a new technique for singling out individual diseased cells and destroying them with tiny explosions.

5 Feb 2010

Michael J. Fox Foundation announces more than $2.8M in awards to discover biomarkers of PD

The Michael J. Fox Foundation for Parkinson's Research today announced more than $2.8 million in awards for 13 new projects to speed the discovery of biomarkers of PD.

4 Feb 2010

CTD seeks small molecule drug discovery and therapeutic antibody targets from academic researchers

A major centre created by the Medical Research Council (MRC) and MRC Technology (MRCT) in order to fast-track the discovery and development of novel drugs, opens its first call for targets today.

4 Feb 2010

Mycobacterium avium infection can result in three different kinds of illness in humans

Through work carried out in connection with her PhD, Tone Bjordal Johansen has shown that Mycobacterium avium does not infect pigs via birds, as previously believed. M. avium can be divided into several subspecies, and the research shows that birds are infected by one particular subspecies, whereas pigs and humans are infected by another.

4 Feb 2010

Amantadine binds to and blocks critical M2 proton channel necessary for influenza virus to infect healthy cells

Antiviral drugs block influenza A viruses from reproducing and spreading by attaching to a site within a proton channel necessary for the virus to infect healthy cells, according to a research project led by Iowa State University's Mei Hong and published in the Feb. 4 issue of the journal Nature.

4 Feb 2010

Around seven in every thousand morbidly obese people are missing part of their DNA

A small but significant proportion of morbidly obese people are missing a section of their DNA, according to research published today in Nature. The authors of the study, from Imperial College London and ten other European Centres, say that missing DNA such as that identified in this research may be having a dramatic effect on some people's weight.

4 Feb 2010

Defective chromosome cause of severe obesity

A new cause of obesity due to a defect on chromosome 16 has just been discovered. It is thought to explain close to 1% of obesity cases. For carriers of the defect, the risk of becoming overweight is 50 times higher. This research is the result of close cooperation between the team of Professor Froguel, a CNRS researcher, in Lille, and colleagues at Imperial College in London and Vaudois University Hospital in Lausanne, with the support of ten other European research groups. The findings of the study are to be published in Nature on February 4, 2010.

4 Feb 2010

Mapping of human genome modification during embryonic development

Scientists at The Genome Institute of Singapore (GIS) and The Scripps Research Institute (TSRI) led an international effort to build a map that shows in detail how the human genome is modified during embryonic development.

4 Feb 2010

Study sheds new light on cancer metastasis

Some cells are natural rule-breakers. Neural crest cells for example, not only migrate throughout the body during development (most cells are more selective in their wandering), they are also more developmentally flexible than their predecessors (a no-no for nearly all cell types).

4 Feb 2010

Medical Science News

New England Biolabs to supply Wellcome Trust Sanger Institute next-generation sequencing library construction reagents

Study suggests molecules and pathways in mood regulation and circadian rhythms are intertwined

Access Pharmaceuticals initiates Cobalamin technology program for targeted delivery of siRNA therapies

Researchers may have discovered how hormone progesterone prevents preterm birth

International Stem Cell opens new cell production facility in Oceanside, California

New research reveals flying bats apply the laws of sonar physics to locate objects in the dark

New class of compound could become effective antidepressant with minimal side effects

iPSC technology for identifying agents that reprogram human somatic cells receives Notice of Allowance

Prehistoric data suggests link between tooth enamel defects and early mortality

Bioheart initiates REGEN Phase I Clinical Trial for testing genetically modified MyoCell in CHF patients

Research could help in developing more effective treatments for wound infections

Scientists discover new technique to destroy individual diseased cells

Michael J. Fox Foundation announces more than $2.8M in awards to discover biomarkers of PD

CTD seeks small molecule drug discovery and therapeutic antibody targets from academic researchers

Mycobacterium avium infection can result in three different kinds of illness in humans

Amantadine binds to and blocks critical M2 proton channel necessary for influenza virus to infect healthy cells

Around seven in every thousand morbidly obese people are missing part of their DNA

Defective chromosome cause of severe obesity

Mapping of human genome modification during embryonic development

Study sheds new light on cancer metastasis

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

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