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Researchers find better way to create iPS cells from blood samples

Researchers at Johns Hopkins have found a better way to create induced pluripotent stem cells-adult cells reprogrammed with the properties of embryonic stem cells-from a small blood sample. This new method, described last week in Cell Research, avoids creating DNA changes that could lead to tumor formation.

2 Feb 2011

Microbubble contrast- enhanced ultrasound improves identification of sentinel lymph node in breast biopsies

Using "microbubbles" and ultrasound can mean more targeted breast biopsies for patients with early breast cancer, helping to determine treatment and possibly saving those patients from undergoing a second breast cancer surgery, a new study in shows.

2 Feb 2011

Study finds treatment-related mortality with bevacizumab in cancer patients

Cancer patients treated with the chemotherapy agent bevacizumab may be at an increased risk of treatment-related death when the drug is used in combination with other therapies.

2 Feb 2011

Bioengineers and physician-scientists zap tumors with light-activated nanoparticles

Rice University bioengineers and physician-scientists at Baylor College of Medicine and Texas Children's Hospital have successfully destroyed tumors of human brain cancer cells in the first animal tests of a minimally invasive treatment that zaps glioma tumors with heat. The tests involved nanoshells, light-activated nanoparticles that are designed to destroy tumors with heat and avoid the unwanted side effects of drug and radiation therapies.

2 Feb 2011

Scientists discover breast cancer cells that dodge immune system, promote tumor growth

Scientists discovered a new way breast cancer cells dodge the immune system and promote tumor growth, providing a fresh treatment target in the fight against the disease. While comparable mechanisms to avoid the immune system have been identified in mice with breast and other cancers, the study tested human breast tumor cells, putting researchers closer to understanding how the disease progresses in real patients.

2 Feb 2011

Scientists test new dry powder measles vaccine that can be inhaled

Sustained high vaccination coverage is key to preventing deaths from measles. Despite the availability of a vaccine, measles remains an important killer of children worldwide, particularly in less-developed regions where vaccination coverage is limited. A team of researchers, led by scientists at the Johns Hopkins Bloomberg School of Public Health and the University of Colorado, developed and successfully tested a dry powder, live-attenuated measles vaccine that can be inhaled.

2 Feb 2011

Research discovers new role of TRPV1 receptors in regulation of locomotor activity

Research by a Barrow Neurological Institute scientist on the thermoregulatory effects of a receptor more commonly studied for its role in pain is the cover story in the Feb. 2 issue of the Journal of Neuroscience.

2 Feb 2011

EA sponsors research grant to investigate specific cancers and kinase mutations

Expression Analysis today announced a jointly sponsored research grant for up to eight American Cancer Society Grantees to investigate and draw parallels between specific cancers and recurring mutations in specific kinases, using targeted genome sequencing.

2 Feb 2011

New compound appears to prevent pain crises in sickle cell disease: GHSU

A new compound appears to prevent the traffic jam of cells that causes debilitating pain crises and associated mortality in sickle cell disease, Georgia Health Sciences University researchers report.

1 Feb 2011

PET imaging may play a role in early evaluation of vandetanib response in thyroid cancer

Positron emission tomography can image metabolic changes following treatment with the protein kinase inhibitor vandetanib, helping to define the therapy response or the effectiveness of the therapeutic agent, according to research published in the February issue of The Journal of Nuclear Medicine.

1 Feb 2011

Fluidigm launches new BioMark HD Real-time PCR System for genomic analysis

Fluidigm today introduced the new BioMark HD Real-time PCR System, the company's most advanced instrument for genomic analysis ever. The BioMark HD System is designed for researchers who require the sensitivity and throughput needed to study gene expression down to the single-cell level -- especially those who have limited amounts of sample or study rare populations of cells.

1 Feb 2011

Vanderbilt researchers announce multi-national collaboration on Alzheimer's disease genetics

Researchers at Vanderbilt University Medical Center, and across the globe, announced today a multi-national collaboration to discover and map all genes relating to Alzheimer's disease through the formation of the International Genomics of Alzheimer's Project.

1 Feb 2011

DRC processors running Smith-Waterman algorithm set new world record

DRC Computer Corporation (DRC), the leading innovator of dynamically reconfigurable processors, announces that it has achieved 9.4 trillion cell updates per second (TCUPS) running the Smith-Waterman algorithm with Affine gap model on the latest DRC Accelium coprocessors.

1 Feb 2011

Scientists successfully crystallise key norovirus enzyme

With the number of norovirus infection cases rising across the country, scientists from the University of Southampton have successfully crystallised a key norovirus enzyme, which could help in the development of a norovirus treatment.

1 Feb 2011

Study establishes direct link between morphine abstinence and depressive-like symptoms

Opiate abuse is a chronic disorder and maintaining abstinence represents a major challenge for addicts.

1 Feb 2011

Gut bacteria may influence mammalian brain development and adult behavior

A team of scientists from across the globe have found that gut bacteria may influence mammalian brain development and adult behavior. The study is published in the scientific journal PNAS, and is the result of an ongoing collaboration between scientists at Karolinska Institutet in Sweden and the Genome Institute of Singapore.

1 Feb 2011

Octreotide inhibits HepG2 proliferation, study confirms

Hepatocellular carcinoma (HCC) is the fifth most common malignancy in the world and is estimated to cause approximately half a million deaths annually. Undoubtedly, the best available treatment for all liver tumors is complete surgical resection. However, the synthetic somatostatin analogue octreotide has been found effective in inhibiting tumor growth in a variety of experimental models. It has been reported that octreotide inhibits the proliferation and induces apoptosis of different HCC cell lines in vitro.

1 Feb 2011

Researchers grow arteries with elasticity of natural blood vessels outside the body

University of Pittsburgh researchers have grown arteries that exhibit the elasticity of natural blood vessels at the highest levels reported, a development that could overcome a major barrier to creating living-tissue replacements for damaged arteries, the team reports in the Proceedings of the National Academy of Sciences.

1 Feb 2011

Specific brain network acts as event monitoring system

Wouldn't life be easy if everything happened as we anticipated? In reality, our brains are able to adapt to the unexpected using an inbuilt network that makes predictions about the world and monitors how those predictions turn out.

1 Feb 2011

Agilent Technologies launches AssayMAP Bravo for protein purification

Agilent Technologies today announced the launch of the AssayMAP Bravo platform and protein purification cartridges, a fully automated solution for high-throughput protein sample preparation and purification.

1 Feb 2011

Medical Science News

Researchers find better way to create iPS cells from blood samples

Microbubble contrast- enhanced ultrasound improves identification of sentinel lymph node in breast biopsies

Study finds treatment-related mortality with bevacizumab in cancer patients

Bioengineers and physician-scientists zap tumors with light-activated nanoparticles

Scientists discover breast cancer cells that dodge immune system, promote tumor growth

Scientists test new dry powder measles vaccine that can be inhaled

Research discovers new role of TRPV1 receptors in regulation of locomotor activity

EA sponsors research grant to investigate specific cancers and kinase mutations

New compound appears to prevent pain crises in sickle cell disease: GHSU

PET imaging may play a role in early evaluation of vandetanib response in thyroid cancer

Fluidigm launches new BioMark HD Real-time PCR System for genomic analysis

Vanderbilt researchers announce multi-national collaboration on Alzheimer's disease genetics

DRC processors running Smith-Waterman algorithm set new world record

Scientists successfully crystallise key norovirus enzyme

Study establishes direct link between morphine abstinence and depressive-like symptoms

Gut bacteria may influence mammalian brain development and adult behavior

Octreotide inhibits HepG2 proliferation, study confirms

Researchers grow arteries with elasticity of natural blood vessels outside the body

Specific brain network acts as event monitoring system

Agilent Technologies launches AssayMAP Bravo for protein purification

Advancing brain microphysiological systems (bMPS)

PhD researcher at LifeArc

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

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