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Engineered TIMPs show promise in fighting glioblastoma invasion

A new research paper was published in Oncotarget, Volume 16, on February 28, 2025, titled "Effect of TIMPs and their minimally engineered variants in blocking invasion and migration of brain cancer cells."

3 Mar 2025

Scientists identify Blastocystis spp. in nearly 10% of edible plants worldwide, highlighting food safety concerns

A new study finds that 9.4% of edible plants worldwide are contaminated with Blastocystis spp., highlighting food safety concerns and the need for improved agricultural hygiene.

3 Mar 2025

Researchers uncover genetic basis of aggressive prostate cancer

Scientists from UCLA, the University of Toronto and the University of Melbourne have uncovered new genetic clues that explain why some prostate cancers remain slow-growing while others become life-threatening.

3 Mar 2025

Researchers uncover key biological mechanism that prevents sperm-egg fusion

A Yale-led research team has uncovered how a naturally occurring biological mechanism found in mammals is able to prevent sperm cells from interacting with an egg, preventing fertilization.

3 Mar 2025

Long-term cocaine use increases impulsivity in rats

Researchers have widely accepted that impulsivity increases the risk of drug addiction, but the evidence to support this belief is mixed.

3 Mar 2025

Brain connectivity could predict adolescent substance use risk

Adolescent substance use is a significant predictor of future addiction and related disorders. Understanding neural mechanisms underlying substance use initiation and frequency during adolescence is critical for early prevention and intervention.

3 Mar 2025

Does a vegetarian diet help or harm your brain? Here’s what the science reveals

A recent study in Nutrients examines the effects of vegetarian and vegan diets on neurological health, highlighting both benefits and potential nutrient deficiencies that impact cognitive function.

3 Mar 2025

Study reveals key cause of ventilator-induced lung injury

A new study from Tulane University suggests that repeated collapse and reopening of tiny alveoli-air sacs in the lungs essential for breathing-during mechanical ventilation may cause microscopic tissue damage, playing a key role in ventilator-related injuries that contribute to thousands of deaths annually.

3 Mar 2025

Cheese isn't just food—it’s a microbiome booster, study confirms

Scientists reveal that cheese-derived bacteria, particularly less abundant strains, can shape gut microbiota and enhance metabolic functions, underscoring the impact of fermented foods on gut health.

3 Mar 2025

Synthetic microbiome therapy offers new hope against C. difficile infections

A synthetic microbiome therapy, tested in mice, protects against severe symptoms of a gut infection that is notoriously difficult-to-treat and potentially life threatening in humans, according to a team of researchers at Penn State.

3 Mar 2025

Study elucidates mechanism behind bacterial cancer therapy

A research team led by Prof. Liu Chenli from the Shenzhen Institutes of Advanced Technology of the Chinese Academy of Sciences (CAS) and Prof. Xiao Yichuan from the Shanghai Institute of Nutrition and Health of CAS elucidated the mechanism behind bacterial cancer therapy using a genetically engineered bacterial strain.

3 Mar 2025

Breakthrough research uncovers way to maintain metabolism during calorie restriction

Many people who have tried to lose weight by cutting calories are familiar with this frustrating reality: at some point, the body stops shedding pounds.

3 Mar 2025

Novel adipose tissue biofabrication approach paves the way for enhanced skin regeneration

The adipose tissue, which serves as an endocrine organ, releases various molecules that regulate the repair of other damaged tissues, including the skin.

3 Mar 2025

Non-invasive 40Hz gamma stimulation could help fight Alzheimer’s

A decade after scientists in The Picower Institute for Learning and Memory at MIT first began testing whether sensory stimulation of the brain's 40Hz "gamma" frequency rhythms could treat Alzheimer's disease in mice, a growing evidence base supporting the idea that it can improve brain health-in humans as well as animals-has emerged from the work of labs all over the world.

3 Mar 2025

Study elucidates mechanism connecting ER membrane remodeling to pyroptosis in cancer cells

Pyroptosis, a highly inflammatory type of programmed cell death, has garnered attention for its potential in cancer treatment.

3 Mar 2025

Novel mechanism of PDHX acetylation linked to hepatocellular carcinoma progression

Cancer cells are known to favor aerobic glycolysis for energy production, a phenomenon termed the Warburg effect.

3 Mar 2025

Co-occurring mutations may limit effectiveness of KRAS G12C inhibitors in colorectal and pancreatic cancer

Colorectal cancer and pancreatic ductal adenocarcinoma that harbored the KRAS G12C mutation often carried other genetic alterations that can be associated with resistance to KRAS G12C inhibitors, despite no prior treatment with this therapy, according to recent results from a large multidatabase analysis.

3 Mar 2025