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The role of geroscience in understanding Alzheimer’s Disease

For more than 30 years, researchers have identified and quantified genetic and lifestyle factors for Alzheimer's Disease (AD) and other dementias. Despite extensive research, the fundamental mechanisms behind these neurodegenerative diseases are still not fully understood, and effective management of AD is taking longer than expected.

10 Oct 2024

Baylor scientist earns NIH grant for personalized microbiome treatments

Baylor University researcher Aaron Wright, Ph.D., has earned a $5.6 million National Institutes of Health (NIH) Director's Transformative Research Award for a project that he and collaborators hope could lead to personalized – and revolutionary – treatments for gut microbiome diseases like Irritable Bowel Syndrome (IBS), Crohn's, Ulcerative Colitis and more.

9 Oct 2024

Scientists detect replication-competent Oropouche virus in semen of traveler, sparking transmission fears

Researchers confirmed the presence of replication-competent Oropouche virus in semen, raising concerns about potential sexual transmission following a traveler's infection.

9 Oct 2024

Pitt researchers validate comprehensive blood test for Alzheimer's biomarkers

University of Pittsburgh scientists independently validated a new blood test platform that can simultaneously measure more than a hundred biomarkers of Alzheimer's disease.

9 Oct 2024

US study uncovers antiviral resistance in swine-origin influenza, urging enhanced pandemic surveillance

Researchers in the US analyzed swine-origin influenza viruses, identifying key mutations that could reduce antiviral drug effectiveness and threaten pandemic preparedness.

9 Oct 2024

Researchers uncover key bacteria driving success of fecal microbiota transplants

Fecal microbiota transplants, or FMTs, are a magic bullet for patients with recurring infections from Clostridioides difficile (C. diff), but researchers are only beginning to understand why.

9 Oct 2024

CRISPR-based rapid molecular diagnostic developed for two forms of leukemia

Researchers at Dana-Farber Cancer Institute have created a CRISPR-based rapid molecular diagnostic for two forms of leukemia that are driven by mutations that involve gene fusions.

9 Oct 2024

Alcohol's effects on embryo development detected in late-gestation placenta

A new study led by Pr. Serge McGraw, researcher at CHU Sainte-Justine and professor at Université de Montréal, shows that the effects of alcohol exposure on an embryo prior to implantation in the uterus can be detected in the late-gestation placenta.

9 Oct 2024

Study illuminates the origin and progression of bladder cancer

How bladder cancer originates and progresses has been illuminated as never before in a study led by researchers at Weill Cornell Medicine and the New York Genome Center.

9 Oct 2024

Study uncovers mechanism of MX protein in fighting HIV-1 and herpes simplex virus

A group of researchers led by Xavier Saelens and Sven Eyckerman at the VIB-UGent Center for Medical Biotechnology discovered how a protein linked to the human immune system wards off HIV-1 and herpes simplex virus-1 by assembling structures in the cell that lure in these viruses and then trap them or even take them apart.

9 Oct 2024

First map of DNA modification in the hippocampus and prefrontal cortex created

A UCLA-led study has provided an unprecedented look at how gene regulation evolves during human brain development, showing how the 3D structure of chromatin -; DNA and proteins -; plays a critical role.

9 Oct 2024

Researchers discover potential therapeutic approach for triple negative breast cancer

Triple negative breast cancer (TNBC) remains the most aggressive and deadly type of breast cancer, but new findings from cancer researchers at Brigham and Women's Hospital, a founding member of the Mass General Brigham healthcare system, are pointing the way toward therapeutic strategies that could be tested in clinical trials in the future.

9 Oct 2024