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Cellumen's Rat Hepatocyte Early Safety Assessment Panel increases predictivity for human DILI

Cellumen, Inc., a discovery and early safety assessment company, today announced that its in vitro Rat Hepatocyte Early Safety Assessment Panel provides increased predictivity for human drug induced liver injury (DILI) equivalent to that of a recently published panel comprised of human hepatocytes. The implications of this study have a significant impact on cost and throughput for in vitro human DILI predictive solutions.

6 Nov 2009

NABT to recognize Leonard C. Yannielli with the 2009 Evolution Education Award

The National Association of Biology Teachers (NABT) will recognize Leonard C. Yannielli, professor of biological sciences at Naugatuck Valley Community College (NVCC) in Waterbury, Connecticut, with the 2009 Evolution Education Award during the NABT annual professional development conference to be held 11-14 November 2009 in Denver, Colorado.

6 Nov 2009

Endothelin increases T cells in the kidneys leading to renal injury

A key player in a cascade that likely begins with stress and leads to high blood pressure and kidney damage has been identified by researchers who say the finding may lead to better ways to control both.

6 Nov 2009

Understanding how regulatory networks drive development

Embryonic development is like a well-organised building project, with the embryo's DNA serving as the blueprint from which all construction details are derived. Cells carry out different functions according to a developmental plan, by expressing, i.e. turning on, different combinations of genes.

6 Nov 2009

Long QT syndrome study reveals importance of genetic testing's role in diagnosing disease

Results of a long QT syndrome (LQTS) study published in the current issue of Circulation play an important role in understanding genetic testing's role in diagnosing disease, according to the senior author, Michael Ackerman, M.D., Ph.D. A pediatric cardiologist at Mayo Clinic, Dr. Ackerman directs Mayo's Long QT Syndrome Clinic and is the director of the Mayo Clinic Windland Smith Rice Sudden Death Genomics Laboratory.

6 Nov 2009

Future for magnetic nanoparticles appears even brighter

Whether it's magnetic nanoparticles (mNPs) giving an army of 'therapeutically armed' white blood cells direction to invade a deadly tumour's territory, or the use of mNPs to target specific nerve channels and induce nerve-led behaviour (such as the life-dependant thumping of our hearts), mNPs have come a long way in the past decade.

6 Nov 2009

USPTO issues patent for Rosetta Genomics' human microRNA miR-193b

Rosetta Genomics, Ltd., a leading developer of microRNA-based molecular diagnostics, announced today that the United States Patent and Trademark Office (USPTO) has issued U.S. Patent No. 7,592,441 to Rosetta Genomics. The patent relates to human microRNA miR-193b, as well as to complementary probes and vectors. This is the third patent issued to Rosetta Genomics by the USPTO.

6 Nov 2009

'Hormone of darkness' melatonin regulates sleep effectively

Melatonin, a natural hormone segregated by the own human body, is an excellent sleep regulator expected to replace somniferous, which are much more aggressive, to correct the sleep/wakefulness pace when human biological clock becomes altered.

6 Nov 2009

New findings may lead to novel therapeutic approaches for HIV and prostate cancer

New Haven, Conn.-Researchers at Yale University have developed synthetic molecules capable of enhancing the body's immune response to HIV and HIV-infected cells, as well as to prostate cancer cells. Their findings, published online in the Journal of the American Chemical Society, could lead to novel therapeutic approaches for these diseases.

6 Nov 2009

Boosting NAD+ after spinal cord injury may prevent permanent nerve death

Substances naturally produced by the human body may one day help prevent paralysis following a spinal cord injury, according to researchers at Weill Cornell Medical College. A recent $2.5 million grant from the New York State Spinal Cord Injury Research Board will fund their research investigating this possibility.

6 Nov 2009

Sirius Genomics signs its first Contribution Agreement with NRC-IRAP

Sirius Genomics, a developer of pharmacogenomic diagnostics, announced today that it has signed its first Contribution Agreement with the National Research Council of Canada Industrial Research Assistance Program (NRC-IRAP). This research funding will be used to study genomic correlations in severe sepsis patients.

6 Nov 2009

Scientists receive $3 million from NIH to uncover how plants make medicinal compounds

Scientists at Michigan State University are receiving nearly $3 million from the National Institutes of Health to uncover how several popular plants make medicinal compounds.

6 Nov 2009

Successful leukemia treatment with a radiolabeled antibody followed by stem cell transplant

For the first time, researchers at Fred Hutchinson Cancer Research Center have reported the use of a radiolabeled antibody to deliver targeted doses of radiation, followed by a stem cell transplant, to successfully treat a group of leukemia and pre-leukemia patients for whom there previously had been no other curative treatment options.

6 Nov 2009

ImmunoLin provides immediate benefit to the function of immune system and gut

A new study provides evidence that ImmunoLin®, an all natural and GRAS approved source of immunoglobulin, will provide immediate benefit to the function of the immune system and the gut. Immunoglobulins, or antibodies, are specialized proteins found in blood that the immune system naturally produces for immunity.

6 Nov 2009

Complete Genomics publishes sequence analysis data from three complete human genomes

Complete Genomics, a third-generation human genome sequencing company, today announced publication of a report in the journal Science describing its proprietary DNA sequencing platform, including analysis of sequence data from three complete human genomes. The consumables cost for these three genomes sequenced on the proof-of-principle genomic DNA nanoarrays ranged from $8,005 for 87x coverage to $1,726 for 45x coverage for the samples described in this report.

6 Nov 2009

Scientists identify new behavioral traits of immune cells; findings may help in understanding complex diseases

In diseases such as multiple sclerosis, cells of the immune system infiltrate the brain tissue, where they cause immense damage. For many years, it was an enigma as to how these cells can escape from the bloodstream. This is no trivial feat, given that specialized blood vessels act as a barrier between the nervous system and the bloodstream.

6 Nov 2009

Newborns' cries already bear the mark of their parents' language, reveals new study

From their very first days, newborns' cries already bear the mark of the language their parents speak, reveals a new study published online on November 5th in Current Biology, a Cell Press publication. The findings suggest that infants begin picking up elements of what will be their first language in the womb, and certainly long before their first babble or coo.

5 Nov 2009

Nanoparticles may cause DNA damage across a cellular barrier

Scientists have shown in the laboratory that metal nanoparticles damaged the DNA in cells on the other side of a cellular barrier. The nanoparticles did not cause the damage by passing through the barrier, but generated signalling molecules within the barrier cells that were then transmitted to cause damage in cells the other side of the barrier.

5 Nov 2009

New biosensor device may help in combating cancer

A powerful new biosensor developed by European researchers will help identify cells in the immune system that actively suppress tumour growth, then put them to use. Enlisting the patient's own immune system would be like sending reinforcements for resistance fighters.

5 Nov 2009

Alnylam Pharmaceuticals presents new data related to its overall delivery research efforts

Alnylam Pharmaceuticals, Inc., a leading RNAi therapeutics company, announced today that it presented new data related to its overall delivery research efforts including the rational design of Mimetic Lipoprotein Particles, or MLPs, a novel technology for the systemic delivery of small interfering RNAs, or siRNAs, the molecules that mediate RNAi.

5 Nov 2009

Medical Science News

Cellumen's Rat Hepatocyte Early Safety Assessment Panel increases predictivity for human DILI

NABT to recognize Leonard C. Yannielli with the 2009 Evolution Education Award

Endothelin increases T cells in the kidneys leading to renal injury

Understanding how regulatory networks drive development

Long QT syndrome study reveals importance of genetic testing's role in diagnosing disease

Future for magnetic nanoparticles appears even brighter

USPTO issues patent for Rosetta Genomics' human microRNA miR-193b

'Hormone of darkness' melatonin regulates sleep effectively

New findings may lead to novel therapeutic approaches for HIV and prostate cancer

Boosting NAD+ after spinal cord injury may prevent permanent nerve death

Sirius Genomics signs its first Contribution Agreement with NRC-IRAP

Scientists receive $3 million from NIH to uncover how plants make medicinal compounds

Successful leukemia treatment with a radiolabeled antibody followed by stem cell transplant

ImmunoLin provides immediate benefit to the function of immune system and gut

Complete Genomics publishes sequence analysis data from three complete human genomes

Scientists identify new behavioral traits of immune cells; findings may help in understanding complex diseases

Newborns' cries already bear the mark of their parents' language, reveals new study

Nanoparticles may cause DNA damage across a cellular barrier

New biosensor device may help in combating cancer

Alnylam Pharmaceuticals presents new data related to its overall delivery research efforts

How can microdialysis benefit drug development

Global and Local Efforts to Take Action Against Hepatitis

Addressing Important Cardiac Biology Questions with Shotgun Top-Down Proteomics

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