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First genome sequence of XDR strain of the bacterium Mycobacterium tuberculosis

An international collaboration led by researchers in the US and South Africa today announced the first genome sequence of an extensively drug resistant (XDR) strain of the bacterium Mycobacterium tuberculosis, one linked to more than 50 deaths in a recent tuberculosis (TB) outbreak in KwaZulu-Natal, South Africa.

21 Nov 2007

Antidepressant drug mianserin extends the lifespan of adult roundworms

A team of scientists led by Howard Hughes Medical Institute (HHMI) investigator Linda B. Buck has found that a drug used to treat depression can extend the lifespan of adult roundworms.

21 Nov 2007

Advancing stem cell research and therapies while fully respecting the dignity of human life

The following statement was released by Cardinal Justin Rigali of Philadelphia, chairman of the Committee for Pro-Life Activities at the United States Conference of Catholic Bishops.

21 Nov 2007

Japanase scientists reprogramme human adult cells to function like pluripotent embryonic stem cells

Acclaimed stem cell researcher Shinya Yamanaka, MD, PhD, has reported that he and his Kyoto University colleagues have successfully reprogrammed human adult cells to function like pluripotent embryonic stem (ES) cells.

21 Nov 2007

Regulation of the retinoic acid gradient in zebrafish embryos

Human embryos that get too much or too little retinoic acid, a derivative of Vitamin A, can develop into babies with birth defects.

21 Nov 2007

New method for detecting and characterizing prions

An effective and sensitive new method for detecting and characterizing prions, the infectious compounds behind diseases like mad cow disease, is now being launched by researchers at Linköping University in Sweden, among other institutions.

21 Nov 2007

Sexy dads produce sexy sons, in the insect world at least

While scientists already knew that specific attractive traits, from cricket choruses to peacocks' tails, are passed on to their offspring, the heritability of attractiveness as a whole is more contentious. Now, new research by the University of Exeter, published (20 November) in Current Biology, shows that attractiveness is hereditary.

21 Nov 2007

Discovery of 300 previously unidentified human genes

Using supercomputers to compare portions of the human genome with those of other mammals, researchers at Cornell have discovered some 300 previously unidentified human genes, and found extensions of several hundred genes already known.

21 Nov 2007

First chemical evidence of a sperm recognition system in the oviducts of pigs

Adding another layer of competition to the mating game, scientists are reporting possible biochemical proof that the reproductive system of female mammals can "sense" the presence of sperm and react to it by changing the uterine environment.

19 Nov 2007

Scientist who created Dolly says stem cells from skin fragments now the way to go

The scientist who created Dolly the sheep says he is abandoning the cloning of human embryos in stem cell research.

19 Nov 2007

ClC-1 helps mice get a move on

In addition to the progressive muscle weakness and degeneration common to all forms of muscular dystrophy, patients with the most common form of muscular dystrophy affecting adults, myotonic dystrophy type 1 (DM1), also experience an inability to voluntarily relax the muscles (a problem known as myotonia).

16 Nov 2007

Stem cells from cloned monkeys - a breakthrough or an ethical nightmare?

In an important breakthrough scientists in the United States have cloned monkey embryos to create embryonic stem cells.

15 Nov 2007

Gene splicing in humans and chimps explains differences

Researchers are closer to understanding why humans differ so greatly from chimpanzees in the way they look, behave, think, and fight off disease, despite having genes that are nearly 99% identical.

15 Nov 2007

Why are males in evolutionary overdrive even though they have essentially the same genes as females?

The observation that males evolve more quickly than females has been around since 19th century biologist Charles Darwin noted the majesty of a peacock's tail feather in comparison with the plainness of the peahen's.

15 Nov 2007

Scientists zero in on the cellular machinery that enables neurons to fire

Toy robots with removable body parts - you probably had fun swapping their heads, imagining how it would affect their behavior. Scientists supported by the National Institutes of Health have been performing similar experiments on ion channels - pores in our nerve cells - to sort out the channels' key functional parts.

15 Nov 2007

Scientists observe how water lubricates the movements of protein molecules

Scientists are one step closer to understanding how proteins move when they perform functions essential for supporting life.

15 Nov 2007

Discovery of key mechanism in bacterial communication

A team of Princeton scientists has discovered a key mechanism in how bacteria communicate with each other, a pivotal breakthrough that could lead to treatments for cholera and other bacterial diseases.

15 Nov 2007

New explanation for how regulatory networks of genes evolved

When ancient retroviruses slipped bits of their DNA into the primate genome millions of years ago, they successfully preserved their own genetic legacy.

15 Nov 2007

New understanding of how bacteria survive in hostile environments

Using an innovative device with microscopic chambers, researchers from four institutions, including Johns Hopkins, have gleaned important new information about how bacteria survive in hostile environments by forming antibiotic-resistant communities called biofilms.

14 Nov 2007

Using neural signals to predict sensory decisions

The rodent whisker sensory system is particularly intriguing because it is "active": the animal generates sensory signals by palpating objects through self-controlled whisker motion (just as we move our fingertips along surfaces to measure their tactile features).

13 Nov 2007