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Brain aging linked to neuronal hyperactivation, not decline, study finds

A study of nematodes by researchers at Nagoya University in Japan has found that aging-related decline in brain function is caused by the excessive activation of certain neurons over time, rather than a decline in neuronal activity.

13 Feb 2025

Takumi-shaped DNA hydrogels show promise for targeted therapies

Hydrogels are polymeric materials with three-dimensional network structures containing large amounts of water. They serve as sustained-release drug delivery systems as they can encapsulate various bioactive substances, including drugs, antigens, and even cells.

13 Feb 2025

KLX mitigates atherosclerotic progression by preventing EndMT

Atherosclerosis, a disease characterized by the accumulation of lipids and inflammatory cells in the arterial wall, is a significant cause of cardiovascular events.

13 Feb 2025

Vaccinations alone may not protect immunocompromised patients, Cambridge research shows

Vaccinations alone may not be enough to protect people with compromised immune systems from infection, even if the vaccine has generated the production of antibodies, new research from the University of Cambridge has shown.

13 Feb 2025

Hybrid closed-loop insulin pumps improve time in range, but increase ketoacidosis

People with type 1 diabetes require continuous insulin treatment and must regularly measure their glucose levels. With open-loop therapies*, insulin administration is manually controlled, while hybrid closed-loop systems* automatically regulate insulin delivery.

13 Feb 2025

Olpasiran significantly lowers "bad cholesterol" linked to cardiovascular risk

The RNA inhibitor olpasiran significantly reduces a type of "bad cholesterol" that's associated with a high risk of cardiovascular events, according to results from an analysis by a Mount Sinai researcher of a phase 2 trial.

13 Feb 2025

Huntsman Cancer Institute improves access for rural cancer patients

Huntsman Cancer Institute at the University of Utah has received a federal contract award that will broaden access to specialized cancer care for Utah's rural and frontier patients.

13 Feb 2025

Babies develop food preferences in the womb, study suggests

Babies show positive responses to the smell of foods they were exposed to in the womb after they are born, according to a new study.

13 Feb 2025

The growing list of human viruses: Are we prepared for the next outbreak?

Researchers review the ever-growing list of human viruses, examining their diversity, transmission pathways, and the urgent need for prevention and global surveillance.

12 Feb 2025

PAC-MANN blood test could help detect pancreatic cancer at early stages

A new blood test could help doctors detect pancreatic cancer earlier, potentially improving survival rates for one of the deadliest cancers.

12 Feb 2025

Multidrug-resistant TB in children is rising: Urgent global action needed

Researchers analyzed global trends in multidrug-resistant tuberculosis (MDR-TB) among children and adolescents, revealing rising incidence rates, gender disparities, and the disproportionate impact on low-income regions.

12 Feb 2025

Study uncovers how MAGE-4 and Pten loss promote aggressive tumor growth

A study published in Science Advances reveals a novel strategy that allows tumors to evade the body's immune response critical for their elimination.

12 Feb 2025

New balance test could help predict falls in older adults

The scenario is common. An elderly person seems to be in good health until one day they suffer a fall and from then on their quality of life begins to deteriorate.

12 Feb 2025

Study identifies vitamin E succinate as key to tumor growth control

High levels of fat mass and obesity-associated protein (FTO) have been linked to increased tumor growth and resistance to immunotherapy.

12 Feb 2025

New insights could help prevent peripheral neuropathy or slow disease onset

An increase in high-fat, high-fructose foods in people's diets has contributed to a dramatic increase in type 2 diabetes.

12 Feb 2025

Blood test can predict preterm preeclampsia with 80% accuracy

A new blood test has an 80% accuracy in predicting preterm preeclampsia, according to a study published today, Feb. 12, in the journal Nature Medicine.

12 Feb 2025

Special zinc-based dissolvable material could transform treatment of broken bones

Monash research could transform how broken bones are treated, with the development of a special zinc-based dissolvable material that could replace the metal plates and screws typically used to hold fractured bones together.

12 Feb 2025

Research explores DNA methylation clock accuracy across tissues

A new research paper was published in Aging (Aging-US) on January 3, 2025, in Volume 17, Issue 1, titled "Characterization of DNA methylation clock algorithms applied to diverse tissue types."

12 Feb 2025

New dual-target therapy offers hope for better breast cancer treatment

Researchers, led by the University of Melbourne's Professor Laura Mackay, a Laboratory Head and Immunology Theme Leader at the Peter Doherty Institute of Infection and Immunity (Doherty Institute), in collaboration with Pfizer, have discovered new insights into possible future treatments for breast cancer.

12 Feb 2025

New discovery could overcome immune therapy failure in ovarian cancer

University of Virginia Cancer Center researchers have explained the failure of immune checkpoint therapy for ovarian cancer by discovering how gut bacteria interfere with the treatment.

12 Feb 2025