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Persistent social and cognitive difficulties linked to poor GCSE results

The combination of poorly developed social and cognitive skills during childhood is linked to poor exam results by the age of 16, with those for whom these issues persist throughout their childhood more than 4 times as likely not to pass at least 5 GCSEs, finds research published online in the Archives of Disease in Childhood.

11 Feb 2025

PDZK1's role in estrogen-induced cholestasis unveiled

Announcing a new publication for Acta Materia Medica journal. Estrogens have been reported to cause dysfunction in biliary transport systems, thereby inducing cholestasis. Multidrug resistance-associated protein 2 (MRP2) is a transporter responsible for independent bile flow.

11 Feb 2025

Cerebral cortex plays key role in memory and novelty detection

The cerebral cortex is the largest part of a mammal's brain, and by some measures the most important. In humans in particular, it's where most things happen-like perception, thinking, memory storage and decision-making.

10 Feb 2025

Neuroscientists discover how the brain corrects visual distortions during movement

Why do our mental images stay sharp even when we are moving fast? A team of neuroscientists led by Professor Maximilian Jösch at the Institute of Science and Technology Austria (ISTA) has identified a mechanism that corrects visual distortions caused by movement in animals.

10 Feb 2025

Your gut bacteria shape your health from childhood to old age, study reveals

Researchers found that gut microbiome composition is strongly linked to metabolic health across different life stages, with greater effects seen in older adults.

10 Feb 2025

Breakthrough study identifies new way to address Alzheimer's at early stages

A team of researchers from the Keck School of Medicine of USC has unlocked the details of a cellular pathway that triggers cellular inflammation and aging and is linked to Alzheimer's disease, particularly among those who carry the APOE4 genetic risk.

10 Feb 2025

Influenza A virus changes shape to evade immune responses

Influenza A virus particles strategically adapt their shape-to become either spheres or larger filaments-to favor their ability to infect cells depending on environmental conditions, according to a new study from National Institutes of Health (NIH) scientists.

10 Feb 2025

High cholesterol diets increase heart attack risk in U.S. veterans, study warns

Higher dietary cholesterol intake is linked to an increased risk of myocardial infarction among U.S. veterans, reinforcing the need for heart-healthy dietary choices.

10 Feb 2025

Study finds cerebellar serotonin as a "brake" to alleviate anxiety

Understanding the neural circuits that drive anxiety may help researchers discover circuit-specific targets and therefore increase the precision of treatment strategies.

10 Feb 2025

Tick-borne encephalitis emerges in Britain: Experts urge vigilance

Tick-borne encephalitis virus (TBEV) has now been confirmed in locally acquired human cases in the U.K., with evidence of established transmission in British tick populations. Increased surveillance and clinician awareness are crucial to detecting and managing this emerging threat.

10 Feb 2025

E64FC26 inhibits inflammation and joint destruction in rheumatoid arthritis models

Protein disulfide isomerases (PDIs) are essential enzymes that facilitate the proper folding of proteins and maintain protein quality within the endoplasmic reticulum.

10 Feb 2025

AI vs. dietitians: Can ChatGPT accurately assess your meals?

Researchers evaluated ChatGPT-4’s accuracy in estimating nutrient content from meal images and found that while it correctly identified foods, it underestimated portion sizes and most nutrients, especially in larger meals.

10 Feb 2025

University of Oulu advances biosensor technology for disease detection

The University of Oulu is at the forefront of developing cutting-edge biosensor technology that could revolutionize the early diagnosis and treatment of diseases.

10 Feb 2025

Research highlights gender and age differences in eye gene therapy responses

Older women could be vulnerable to harmful inflammation from new gene therapies to treat incurable eye diseases, new research has found.

10 Feb 2025

Novel MSC-based therapy provides hope for ocular GVHD treatment

Graft-versus-host disease (GVHD) is a common and severe complication that occurs after stem cell transplantation, where the donor's immune cells attack the recipient's tissues.

10 Feb 2025

New biomarker test detects early tau tangles in Alzheimer's disease

Years before tau tangles show up in brain scans of patients with Alzheimer's disease, a biomarker test developed at the University of Pittsburgh School of Medicine can detect small amounts of the clumping-prone tau protein and its misfolded pathological forms that litter the brain, cerebrospinal fluid and potentially blood, new research published today in Nature Medicine suggests.

10 Feb 2025