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The thalamus could be a strategic target for treating cognitive dysfunction

Years ago, as a neurology resident, Chinfei Chen, MD, PhD, cared for a 20-year-old woman who had experienced a very small stroke, affecting only the thalamus.

7 Apr 2025

Breakthrough protein offers new hope for pulmonary sarcoidosis treatment

Pulmonary sarcoidosis is a lung disease characterized by granulomas-tiny clumps of immune cells that form in response to inflammation.

7 Apr 2025

Vitamin C from fresh foods helps lower heart disease risk in type 2 diabetes

Low vitamin C levels are linked to higher cardiovascular disease prevalence in people with type 2 diabetes. Fresh fruit and vegetable intake is associated with higher vitamin C levels and may offer protective cardiovascular effects.

7 Apr 2025

Blood test breakthrough pinpoints 70 proteins linked to asthma risk in major genetic study

Researchers used UK Biobank data to identify 70 proteins with genetically predicted roles in asthma, offering insights into disease mechanisms.

7 Apr 2025

Genetic pathways explain why some people grow tall and others stay short

A landmark review in Nature Reviews Genetics dissects the rare and common genetic variants that shape human height. The paper explains how monogenic and polygenic factors converge on key growth pathways and influence disease risk.

7 Apr 2025

Bone aging is more complex than previously thought

A new research paper was published in Aging (Aging-US) on March 18, 2025, in Volume 17, Issue 3, titled "Mitochondrial oxidative stress or decreased autophagy in osteoblast lineage cells is not sufficient to mimic the deleterious effects of aging on bone mechanoresponsiveness."

7 Apr 2025

Simple blood test improves prediction of heart attack and stroke risk

A simple £5 blood test for the protein troponin could predict a person's risk of heart attacks and strokes with greater accuracy than ever before, research suggests.

7 Apr 2025

New neurons rebuild damaged circuits in Huntington’s disease

New research shows that the adult brain can generate new neurons that integrate into key motor circuits. The findings demonstrate that stimulating natural brain processes may help repair damaged neural networks in Huntington's and other diseases.

7 Apr 2025

Predicting treatment failure in cutaneous leishmaniasis with precision medicine

Nearly one million people worldwide are plagued annually by cutaneous leishmaniasis, a devastating skin infection caused by the Leishmania parasite.

7 Apr 2025

Research uncovers root cause of gland damage in Sjögren's syndrome

Sjögren's syndrome is a chronic autoimmune disorder that affects millions worldwide, especially women, causing unrelenting dryness of the mouth and eyes.

7 Apr 2025

Brain health in older adults threatened by prolonged air pollution

Long-term exposure to high levels of air pollution may harm the brain health of older adults in England, finds a new study led by UCL researchers.

7 Apr 2025

New antibody research sparks hope for better whooping cough vaccines

Whooping cough, or pertussis, was once a leading cause of death for children in the U.S. and worldwide before the introduction of vaccines in the 1940s.

7 Apr 2025

Lower LDL cholesterol linked to reduced dementia risk

Researchers investigate the potential association between LDL-C levels and the risk of dementia.

7 Apr 2025

Scientists engineer promising vaccine target for Lyme disease

Meeting the unmet need for a vaccine is the top priority for researchers studying Lyme disease, which infects about 476,000 people in the U.S. each year and can come with severe complications such as ongoing fatigue and joint issues.

7 Apr 2025

High-fat diet fuels cancer spread via rogue platelets

Researchers explore the role of a high-fat diet in promoting the formation of premetastatic niches and platelet activation.

7 Apr 2025

Mpox virus poses rising global epidemic and pandemic threat

Insufficient research on mpox hinders effective control strategies, emphasizing the need to understand its transmission and immune response mechanisms.

7 Apr 2025

Healthy Beginnings, Hopeful Futures: A Conversation with WHO’s Dr. Allotey

Dr. Pascale Allotey advocates for comprehensive maternal health policies, stressing the importance of women's voices in shaping effective healthcare solutions.

7 Apr 2025

Even rich Americans live shorter lives than poor Europeans, study finds

Wealthier individuals aged 50–85 had lower mortality across both the U.S. and Europe, but survival disparities were far greater in the U.S. Even the richest Americans fared no better than the poorest in Northern and Western Europe, highlighting systemic health inequalities.

7 Apr 2025

Gut bacteria and blood metabolites directly affect children’s height, study finds

Researchers used Mendelian randomization to uncover causal links between gut microbiota, blood metabolites, and short stature in children.

7 Apr 2025

Two-week diet swap reveals stark difference: Western vs. African heritage diets on immunity

Researchers conducted a randomized controlled trial in Tanzania to examine how switching between African heritage and Western diets affects immune and metabolic health. They found that a Western diet increases inflammation and disease risk, while heritage diets and fermented beverages like Mbege have anti-inflammatory benefits.

7 Apr 2025