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TYK2 inhibition may offer new strategy to reduce tau toxicity in Alzheimer's

Researchers at Baylor College of Medicine, the Jan and Dan Duncan Neurological Research Institute (Duncan NRI) at Texas Children's Hospital and collaborating institutions discovered that the enzyme TYK2 transforms the normal protein tau into one that accumulates in the brain and contributes to the development of Alzheimer's disease in animal models.

12 Nov 2024

Integrating traditional medicines with modern nutrition for holistic health

In recent years, there has been a rising interest in combining traditional natural medicines with essential nutrients to foster a holistic approach to human health.

12 Nov 2024

Key reason why some cancers do not respond to immunotherapy identified

Research reveals SLC13A3's role in tumor cell survival and immune therapy resistance, highlighting its potential as a target for improved cancer treatments.

12 Nov 2024

Mitochondria’s division of labor sheds light on how cancer cells survive harsh conditions

Research shows mitochondria form distinct subpopulations under nutrient stress, revealing survival mechanisms in cancer cells and potential therapeutic targets.

12 Nov 2024

Scientists uncover a previously unrecognized tumor suppression mechanism

There are processes in the human body that can suppress the growth and proliferation of cancer cells. These mechanisms, including those involving the tumor suppressor protein p53, are widely studied due to their critical role in disease.

12 Nov 2024

Patient-derived organoids: Transforming cancer research and personalized medicine

Patient-derived organoids (PDOs) are revolutionizing cancer research, enhancing drug testing and personalized treatment through advanced 3D modeling techniques.

12 Nov 2024

Pfizer-BioNTech vaccine provides strong protection against MIS-C in children aged 5–17

Research indicates the Pfizer-BioNTech vaccine effectively reduces MIS-C incidence in children, supporting vaccination as a critical public health measure.

12 Nov 2024

Limited impact of prenatal COVID-19 exposure on child neurodevelopmental outcomes

Research shows prenatal exposure to SARS-CoV-2 linked to slight regulatory behavior improvements in infants, but no significant neurodevelopmental impacts.

12 Nov 2024

Ultra-processed food linked to weight gain and lower well-being in adolescents

Investigating ultra-processed food and screen time, this study examines their effects on weight and well-being in adolescents, considering maternal education.

12 Nov 2024

MethylGPT unlocks DNA secrets for age and disease prediction

Researchers developed MethylGPT, a powerful transformer-based model that identifies DNA methylation patterns, enabling advanced age and disease prediction with clinical potential.

11 Nov 2024

AI-based ultrasound software guides childbirth decisions with high accuracy

A new AI-based software has been developed that can be integrated with an ultrasound device to 'guide' childbirth by providing precise, real-time information on the baby's head position.

11 Nov 2024

Revolutionary AI predicts aging and disease from DNA patterns

Researchers developed CpGPT, a novel foundation model for DNA methylation analysis that captures sequence, positional, and epigenetic context to predict aging and disease risks. This model offers breakthroughs in imputing missing data and improving mortality and morbidity predictions.

11 Nov 2024