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Generative AI creates life-saving antibiotics from scratch

What if generative AI could design life-saving antibiotics, not just art and text? In a new Cell Biomaterials paper, Penn researchers introduce AMP-Diffusion, a generative AI tool used to create tens of thousands of new antimicrobial peptides (AMPs) - short strings of amino acids, the building blocks of proteins - with bacteria-killing potential.

2 Sep 2025

Single-cell transcriptomics reveals new players in liver regeneration

The liver is remarkable for its ability to regenerate after injury, yet when this process fails, acute liver failure (ALF) carries devastating outcomes.

2 Sep 2025

Study reveals how dormant E. coli bacteria survive antibiotics

A groundbreaking study by researchers from Wuhan University, York University (UK), and Peking University has uncovered how Escherichia coli (E. coli) persister bacteria survive antibiotics by protecting their genetic instructions.

2 Sep 2025

Exosomes carry key indicators of biological aging

A new research paper featured on the cover of Volume 17, Issue 8 of Aging (Aging-US) was published on July 30, 2025, titled "Exosomes released from senescent cells and circulatory exosomes isolated from human plasma reveal aging-associated proteomic and lipid signatures."

2 Sep 2025

Plant-derived carotenoid found to boost immune response against cancer

In a new study, researchers from the University of Chicago discovered that zeaxanthin, a plant-derived carotenoid best known for protecting vision, may also act as an immune-boosting compound by strengthening the cancer-fighting activity of immune cells.

2 Sep 2025

Researchers reveal how diseases interact at the genetic level

2 Sep 2025

PEPITEM shows promise in treating osteoporosis by enhancing bone health

Researchers from the University of Birmingham, U.K., have identified bioactive peptide sequences in PEPITEM molecule, and demonstrated the biological of activity of the full PEPITEM molecule in counteracting key changes caused by osteoporosis.

2 Sep 2025

Heparanase 2 emerges as key protector of blood vessel integrity

An international research team led by MDI Biological Laboratory President Hermann Haller, M.D. and postdoctoral researcher Yannic Becker, Ph.D. has discovered that a little-known molecule, heparanase 2 (Hpa2), plays a critical role in maintaining blood vessels' integrity.

2 Sep 2025

MicroRNA panels show promise for improving prostate cancer diagnosis

Prostate cancer is highly heterogeneous, ranging from slow-growing tumors to aggressive, life-threatening disease.

2 Sep 2025

New technique succeeds in studying embryo implantation outside the body

The use of assisted reproductive technologies like in vitro fertilization is becoming more common worldwide. However, while these technologies successfully create viable embryos, a little over half of all embryos are lost because they fail to implant into the uterus.

2 Sep 2025

Nanostructures boost CRISPR delivery for genetic medicine

With the power to rewrite the genetic code underlying countless diseases, CRISPR holds immense promise to revolutionize medicine. But until scientists can deliver its gene-editing machinery safely and efficiently into relevant cells and tissues, that promise will remain out of reach.

2 Sep 2025

New insights into early brain circuit breakdown in Alzheimer’s

One of the first parts of the brain affected by Alzheimer's disease is the entorhinal cortex - a region that plays a big role in memory, spatial navigation, and the brain's internal mapping system.

2 Sep 2025

Aptamer signs therapeutic development agreement with Invizius

Aptamer Group plc, the developer of next-generation synthetic binders for the life sciences industry, is pleased to announce that it has signed a new therapeutic development agreement with Invizius, a clinical-stage biotechnology company focused on second-generation complement system therapies for inflammatory, fibrotic, and autoimmune diseases.

From Aptamer Group 2 Sep 2025

AI model predicts flu vaccine strains more accurately than WHO

AI-based models like VaxSeer outperform traditional methods in flu vaccine strain selection, enhancing effectiveness and addressing global influenza challenges.

2 Sep 2025

Depressive symptoms may interfere with learning to actively avoid unpleasant events

Depression alters how people pursue rewards, but, conversely, whether depressive symptoms influence how people learn to avoid nonrewarding, unpleasant events is less clear.

1 Sep 2025

Brain pulsations driving glymphatic function differ in narcolepsy patients and healthy individuals

A hormone produced by the brain, orexin, may play a central role in the functioning of the brain’s glymphatic system, which clears waste, according to a new study from the University of Oulu.

1 Sep 2025

Glutamate receptors found to drive pediatric brain tumor development

The most common type of brain tumor in children, pilocytic astrocytoma (PA), accounts for about 15% of all pediatric brain tumors.

1 Sep 2025

Exploring testosterone's influence on cardiovascular, metabolic, reproductive, and mental health

For decades, testosterone has been recognized as the primary driver of male reproductive development and secondary sex characteristics.

1 Sep 2025

Review maps Toxoplasma hotspots: Half in Eastern Europe infected by age 44

Researchers systematically reviewed and modeled Toxoplasma gondii seroprevalence across 25 European countries. The study found striking regional differences, with highest infection levels in eastern and western Europe and lowest in the UK and northern regions.

1 Sep 2025

Can honey protect your brain? Study reviews its potential against Alzheimer's

This review examined 27 preclinical studies on honey and Alzheimer’s disease, showing honey’s bioactive compounds counter oxidative stress, inflammation, and amyloid buildup. Despite promising lab results, no human trials exist, underscoring the need for clinical research.

1 Sep 2025