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RNA nanoparticles offer dual action against prostate tumors

Yang Zhang, PhD, and Jinjun Shi, PhD, both of the Center for Nanomedicine and Department of Anesthesiology, Perioperative and Pain Medicine at Brigham and Women's Hospital, are co-senior authors of a paper published in ACS Nanoscience Au, "Lipid Nanoparticle Delivery of mRNA and siRNA for Concurrent Restoration of Tumor Suppressor and Inhibition of Tumorigenic Driver in Prostate Cancer."

10 Jan 2025

Hormonal changes after menopause impact multiple sclerosis severity

A new study by UC San Francisco has found that menopause revs up the progression of multiple sclerosis (MS).

10 Jan 2025

Mussel-inspired nanoparticles for targeted lung cancer therapy

Researchers from POSTECH and Kyungpook National University have developed a novel inhalable therapeutic delivery system for lung cancer, leveraging mucoadhesive protein nanoparticles inspired by the adhesive properties of marine mussels.

9 Jan 2025

Developing and refining muscle atrophy models for drug discovery

With the intensification of global population aging, muscle atrophy, characterized by the loss of muscle mass and function, has become an important health issue affecting the elderly. Researchers have widely used various animal and cellular models to gain a deeper understanding of the pathophysiological mechanisms of muscle atrophy and develop effective treatment strategies.

9 Jan 2025

Could autophagy enhancement slow aging and combat Alzheimer's?

How cellular cleanup systems could hold the key to slowing aging and halting neurodegeneration.

9 Jan 2025

The X factor: Decoding brain aging differences between men and women

Researchers unveil how biological sex influences brain aging, revealing genetic, hormonal, and molecular mechanisms behind cognitive resilience and decline.

9 Jan 2025

New skeletal tissue could revolutionize regenerative medicine and cartilage repair

An international research team led by the University of California, Irvine has discovered a new type of skeletal tissue that offers great potential for advancing regenerative medicine and tissue engineering.

9 Jan 2025

Aircraft noise pollution harms arteries, but heart drugs show promise in animal model research

Alpha- and beta-blockers reduce oxidative stress and inflammation caused by aircraft noise but fail to prevent hypertension, highlighting their potential to protect vascular health in noise-exposed individuals.

9 Jan 2025

Electrical stimulation proven to increase muscle mass and strength

If building strength and muscle mass is part of your New Year's Resolution, you may want to add a new routine to your workout.

9 Jan 2025

$20 million grant to explore the role of viruses in human health

For over a decade, scientists have studied the microbiome, the environment of microorganisms that live on and in the body, and how it affects health and disease.

9 Jan 2025

Can AI chatbots master the science of dietary balance?

Discover how AI chatbots are reshaping weight-loss planning with precision and variety, yet face challenges in balancing macronutrients for optimal health.

9 Jan 2025

Research from second pig heart transplant provides new directions for xenotransplantation

Continuing significant advancements in the field of xenotransplantation, surgeon-scientists from the University of Maryland School of Medicine provided an extensive analysis on the second patient in the world to receive a genetically-modified pig organ.

9 Jan 2025

How stress fuels allergic skin inflammation

Researchers investigate the cellular and molecular mechanisms through which stress exacerbates immunoglobulin E cutaneous allergic inflammation.

9 Jan 2025

Targeting miR-4274 and PEX5 can help overcome radioresistance in colorectal cancer

Colorectal cancer (CRC) is a global health concern, and despite advances in radiotherapy, endogenous radioresistance in CRC patients remains a challenge.

9 Jan 2025

Study reveals widespread microplastic contamination in U.S. West Coast fish and shellfish

Researchers measure the levels of anthropogenic particles present in various seafood caught along the West Coat of the United States.

9 Jan 2025

Study links fiber consumption to epigenetic changes with anti-cancer effects

Fiber is well known to be an important part of a healthy diet, yet less than 10% of Americans eat the minimum recommended amount.

9 Jan 2025

New molecule shows promise in protecting mice from influenza

Researchers at the University of Gothenburg, Sweden, in collaboration with colleagues in China, have discovered an antibody-like molecule that can protect mice from various influenza viruses.

9 Jan 2025

Gut microbes and the body work together to regulate fat metabolism

Beneficial gut microbes and the body work together to fine-tune fat metabolism and cholesterol levels, according to a new preclinical study by investigators from Weill Cornell Medicine and the Boyce Thompson Institute at Cornell University's Ithaca campus.

9 Jan 2025

Unraveling the push-pull mechanism of neuron migration

The journey of a thousand miles begins with a single step, but for developing neurons, this first step relies on collaboration from multiple signaling pathways.

9 Jan 2025

Oral medications less effective than insulin for preventing large babies in gestational diabetes study

A study comparing oral glucose-lowering agents to insulin for gestational diabetes found no non-inferiority in preventing large-for-gestational-age infants.

9 Jan 2025