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Largest genetic study on circulating retinol reveals new insights into its impact on health

Study presents the largest genome-wide association analysis on circulating retinol, identifying genes beyond the primary transport system that influence retinol levels and its broad impacts on health, including potential protective roles against schizophrenia and effects on various clinical phenotypes.

21 Feb 2024

Unlocking non-hormonal male contraception with HDAC inhibitors

Surveys show most men in the United States are interested in using male contraceptives, yet their options remain limited to unreliable condoms or invasive vasectomies.

20 Feb 2024

Women gain more health benefits from exercise than men

Women experience greater health benefits from physical activity than men, suggesting a need to encourage more women to engage in exercise to reduce cardiovascular and all-cause mortality.

20 Feb 2024

Finasteride may offer life-saving benefits beyond hair loss treatment

The drug finasteride, also known as Propecia or Proscar, treats male pattern baldness and enlarged prostate in millions of men worldwide.

20 Feb 2024

Physical activity counters social isolation's mental toll

Physical activity significantly offsets the negative impact of social isolation on mental health, with neuroimaging showing its potential as a compensatory mechanism for emotional well-being.

20 Feb 2024

Ultra-processed foods linked to higher risk of sarcopenia

Study finds a direct correlation between ultra-processed food consumption and increased risk of low muscle mass in adults, suggesting dietary changes could combat sarcopenia.

20 Feb 2024

Functional brain changes linked to depression exposure

Study reveals that exposure to depression correlates with significant functional brain changes, varying by depression definition, without notable structural differences, emphasizing the need for precise diagnostic criteria to enhance treatment outcomes.

20 Feb 2024

“Laboratory testicles” could solve male infertility mysteries

The testis is responsible for sperm production and testosterone synthesis. Abnormalities in testis development and function lead to disorders of sex development (DSD) and male infertility. Currently, no in vitro system exists for modeling the testis.

20 Feb 2024

Adolescent males with anorexia nervosa have higher mortality rates

Anorexia nervosa affects males as well as females, and affected males have a sixfold higher mortality rate than males in the general population. A new article published in CMAJ (Canadian Medical Association Journal) aims to raise awareness of this life-threatening eating disorder.

20 Feb 2024

High-intensity exercise affects motor skill learning in older adults

High-intensity interval training (HIIT) enhances early offline motor skill consolidation in older adults but may impair immediate motor skill acquisition, challenging previous assumptions about exercise's universal benefits on motor learning.

19 Feb 2024

Is snoring related to high blood pressure?

Home-based monitoring reveals a strong link between snoring duration and uncontrolled hypertension, highlighting the need for snoring to be considered in hypertension management.

19 Feb 2024

Mediterranean diet linked to better semen quality, study finds

A systematic review reveals that adherence to the Mediterranean diet improves semen quality in men of reproductive age, suggesting a positive impact on male reproductive health.

19 Feb 2024

New RNA therapy zilebesiran shows promise in lowering blood pressure

Zilebesiran, an RNA interference therapeutic, significantly reduces blood pressure in hypertension patients with a favorable safety profile, offering a potential biannual treatment option.

19 Feb 2024

COVID-19 linked to higher fatigue rates, says study

A study by the CDC and Washington University found COVID-19 significantly increases the risk of developing fatigue and chronic fatigue, with higher incidence rates compared to non-COVID-19 controls.

19 Feb 2024

Healthy lifestyles linked to specific metabolic markers, large study finds

Researchers identify metabolomic markers linked to healthy lifestyles in a large study, showing a connection between lipid metabolism and reduced mortality risks.

18 Feb 2024

Long COVID prevalence varies widely across US states, CDC study finds

The CDC's nationwide study reveals varying long COVID prevalence across the USA, from 1.9% in the Virgin Islands to 10.6% in West Virginia, underscoring the need for targeted public health strategies.

18 Feb 2024

New study pinpoints key markers for Long COVID diagnosis

Study identifies elevated serologic responses and memory CD8+ T cell clonal expansion as key markers of Long COVID, offering insights into its pathology and potential diagnostic approaches.

18 Feb 2024

Pilates lowers blood pressure in hypertensive patients, study finds

Pilates training programs are deemed safe and effective for managing blood pressure in hypertensive patients, offering a viable rehabilitation option alongside traditional treatments.

18 Feb 2024

Neoadjuvant chemotherapy shows promise for advanced penile cancer

Penile squamous cell carcinoma is a rare malignancy with limited treatment options and poor prognosis, especially in advanced stages. Because of its rarity, few studies focus on better understanding and managing this disease.

16 Feb 2024

Ketogenic diet shows promise in curbing cravings in alcohol use disorder patients

Study found that a ketogenic diet (KD) significantly increased serum beta-hydroxybutyrate levels, suggesting nutritional ketosis, and showed a trend towards reducing self-reported alcohol craving and a neurobiological craving signature (NCS) for alcohol in patients with alcohol use disorder (AUD), indicating its potential to modulate alcohol craving.

14 Feb 2024