Molecular & Structural Biology

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RNA-targeting compound restarts a healing factor silenced by heart attack

A heart attack can leave parts of the heart permanently scarred and stiff, resulting in prolonged disability and potential progression toward heart failure. Scientists have studied various ways to repair or regenerate such damaged heart tissue, with limited success.

24 Aug 2020

Faulty RNA quality control system leads to haywire production of toxic proteins in FTLD/ALS

Researchers at Osaka University identify vicious cycle involving RNA exosome that accelerates disease progression in FTLD/ALS

24 Aug 2020

New bioluminescent reporter developed to track DNA double stranded break repair

A new bioluminescent reporter that tracks DNA double stranded break repair in cells has been developed by researchers from Massachusetts General Hospital and the Academia Sinica in Taiwan.

21 Aug 2020

Ciliary proteins play vital role in cardiovascular functions and genetic diseases

Research from Chapman University provides new insight into the characteristics of crucial proteins within the ciliary membrane that play vital roles in human genetic diseases and cardiovascular functions.

20 Aug 2020

UT leads new project to explore the mysteries of brain connections

Researchers at The University of Texas at Austin will lead an ambitious new project with 10 other U.S. institutions and global partners that has significant implications for understanding human brain health.

19 Aug 2020

Study sheds light on 500-year old mystery about the human heart

Researchers have investigated the function of a complex mesh of muscle fibres that line the inner surface of the heart. The study, published in the journal Nature, sheds light on questions asked by Leonardo da Vinci 500 years ago, and shows how the shape of these muscles impacts heart performance and heart failure.

19 Aug 2020

RNA-based therapeutic approach holds promise as potential cure for hereditary diseases

ETH Zurich scientists have developed an RNA molecule that can be used in bone marrow cells to correct genetic errors that affect protein production.

18 Aug 2020

Researchers solve a long-held mystery of X chromosome inactivation

Researchers at Massachusetts General Hospital (MGH) have solved a mystery that has long puzzled scientists: How do the bodies of female humans and all other mammals decide which of the two X chromosomes it carries in each cell should be active and which one should be silent?

18 Aug 2020

Switching off 'master regulator' may protect critical brain cells from Parkinson's-related damage

Switching off a molecular "master regulator" may protect the brain from inflammatory damage and neurodegeneration in Parkinson's disease, reports a study published today in Nature Neuroscience.

17 Aug 2020

New technique enables real-time observation of influenza A hemagglutinin during viral entry

Unlike living organisms, to avoid extinction, viruses need to hijack living host machineries to generate new viruses.

17 Aug 2020

Remains of 17th century Bishop provide insights into the origins of tuberculosis

Bishop Peder Winstrup of Lund, Sweden passed away in the winter of 1679 at the age of 74 and was interred in a crypt at Lund Cathedral.

15 Aug 2020

Understanding the relationship between movement and vision

To get a better look at the world around them, animals constantly are in motion. Primates and people use complex eye movements to focus their vision (as humans do when reading, for instance); birds, insects, and rodents do the same by moving their heads, and can even estimate distances that way.

15 Aug 2020

Scientists hope to find clues about how life emerged by tinkering with its oldest components

"I'm fascinated with life, and that's why I want to break it."

15 Aug 2020

Chemists create complex, oxygen-containing molecules that are normally made by plants

Chemists at Scripps Research have efficiently created three families of complex, oxygen-containing molecules that are normally obtainable only from plants.

14 Aug 2020

Research shows how a protein stops cells from attacking their own DNA

Viruses multiply by injecting their DNA into a host cell. Once it enters the intracellular fluid, this foreign material triggers a defense mechanism known as the cGAS-STING pathway.

14 Aug 2020

UD researchers gain new insights into hepatitis B virus' genetic blueprint

Researchers at the University of Delaware, using supercomputing resources and collaborating with scientists at Indiana University, have gained new understanding of the virus that causes hepatitis B and the "spiky ball" that encloses the virus's genetic blueprint.

13 Aug 2020

Engineered capsids for improved gene delivery to the retina and cornea

A rational design approach created novel variants of adeno-associated viral (AAV) capsids.

13 Aug 2020

Natural controllers shed light on immunity mechanisms against hepatitis B

Infections in humans caused by the hepatitis B virus (HBV) represent a major public health problem. Despite the availability of effective protective vaccines, more than 250 million individuals worldwide are chronically infected according to WHO estimates.

13 Aug 2020

Research reveals how quickly pre-cancerous skin lesions can form on the DNA

Luis Ortiz-Rodríguez grew up on the beaches of Puerto Rico--surfing, swimming and running in the hot sand--and swears he had never put on sunblock a day in his life.

13 Aug 2020

Researchers identify a protein that facilitates spread of SARS-CoV-2 virus through cells

Eric Ross and Sean Cascarina, biochemistry and molecular biology researchers at Colorado State University, have released a research paper identifying a protein encoded by SARS-CoV-2, the virus that causes COVID-19, that may be associated with the quick spread of the virus through cells in the human body.

13 Aug 2020

Molecular & Structural Biology

RNA-targeting compound restarts a healing factor silenced by heart attack

Faulty RNA quality control system leads to haywire production of toxic proteins in FTLD/ALS

New bioluminescent reporter developed to track DNA double stranded break repair

Ciliary proteins play vital role in cardiovascular functions and genetic diseases

UT leads new project to explore the mysteries of brain connections

Study sheds light on 500-year old mystery about the human heart

RNA-based therapeutic approach holds promise as potential cure for hereditary diseases

Researchers solve a long-held mystery of X chromosome inactivation

Switching off 'master regulator' may protect critical brain cells from Parkinson's-related damage

New technique enables real-time observation of influenza A hemagglutinin during viral entry

Remains of 17th century Bishop provide insights into the origins of tuberculosis

Understanding the relationship between movement and vision

Scientists hope to find clues about how life emerged by tinkering with its oldest components

Chemists create complex, oxygen-containing molecules that are normally made by plants

Research shows how a protein stops cells from attacking their own DNA

UD researchers gain new insights into hepatitis B virus' genetic blueprint

Engineered capsids for improved gene delivery to the retina and cornea

Natural controllers shed light on immunity mechanisms against hepatitis B

Research reveals how quickly pre-cancerous skin lesions can form on the DNA

Researchers identify a protein that facilitates spread of SARS-CoV-2 virus through cells

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

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