Molecular & Structural Biology

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New strategies can help increase the efficiency of artificial cell reprogramming

Maria-Elena: Can you imagine being able to artificially generate cells that can develop into any cell type? That would be really fantastic! We call this ability 'totipotency' and it is the highest level of cellular plasticity.

6 Jul 2020

UCLA scientists identify new function for histones

UCLA scientists have identified a new function for histones, the spool-shaped proteins that regulate gene expression and serve as anchors for strands of DNA to wrap around.

2 Jul 2020

Researchers unravel how the body fights off urinary tract infections

Anyone who has ever had cystitis knows that urinary tract infections of this kind are annoying and painful. They can be well treated by antibiotics, but may be fatal if left untreated.

2 Jul 2020

Studies show how individual cells maintain their internal clocks

Two new studies led by UT Southwestern scientists outline how individual cells maintain their internal clocks, driven both through heritable and random means.

2 Jul 2020

New technology can increase the quality of stem cells used in regenerative medicine

Stem cells have been holding great promise for regenerative medicine for years. In the last decade, several studies have shown that this type of cell, which in Spanish is called "mother cell" because of its ability to give rise to a variety of different cell types, can be applied in regenerative medicine for diseases such as muscular and nervous system disorders, among others.

2 Jul 2020

Developing Vaccines and Therapeutics by Exploiting Structure in Spherical Nucleic Acids

An interview discussing the use of spherical nucleic acids (SNAs) and what they show about the importance of structure in pharmaceutical development.

From Pittcon 2 Jul 2020

CityU develops CRISPR-assisted method to identify RNA-binding proteins in living cells

While scientists still don't fully understand the diverse nature of RNA molecules, it is believed that the proteins binding to them, called RNA-binding proteins, are associated with many disease formation.

1 Jul 2020

Researchers discover a protein that protects B cells from stress-induced cell death

Whenever a germ gets into the human body, the immune system usually responds immediately to fight off the enemy attacker. One of our defense system's most important strategies involves B lymphocytes, also known as B cells, which produce antibodies that target and neutralize pathogens.

1 Jul 2020

Research shows how a protein's small change leads to big trouble for cells

In molecular biology, chaperones are a class of proteins that help regulate how other proteins fold. Folding is an important step in the manufacturing process for proteins. When they don't fold the way they're supposed to, it can lead to the development of diseases such as cancer.

30 Jun 2020

A data-rich atlas of the developing human brain

For the nascent brain of a human embryo to develop into the complex organ that controls human consciousness, a finely tuned sequence of genetic events has to take place; hundreds of genes are activated and deactivated in a precise symphony.

30 Jun 2020

Study uncovers algorithms and neural circuit mechanisms of escape responses

Ordered and variable animal behaviours emerge to explore and adapt to the environment. They are generally considered as the combination of a series of stereotyped motor primitives. However, how the nervous system shapes the dynamics of motor sequences remains to be solved.

29 Jun 2020

Scientists discover osmotic stress as stimulator of cellular waste disposal

Cellular waste disposal, where autophagy and lysosomes interact, performs elementary functions, such as degrading damaged protein molecules, which impair cellular function, and reintroducing the resulting building blocks such as amino acids into the metabolic system.

29 Jun 2020

Biophysicists propose a simple way to observe heart tissue

Biophysicists from the Moscow Institute of Physics and Technology and their colleagues have proposed a simple way to observe the heart tissue.

29 Jun 2020

Researchers provide mechanistic insight into protein co-aggregation in Alzheimer's disease

A research team lead by Ludmilla Morozova Roche at Umeå University, Sweden, has provided the mechanistic insight into protein co-aggregation in Alzheimer's disease.

26 Jun 2020

New steroid compounds from deep-water starfish show anticancer activity

Russian scientists from Far Eastern Federal University, G. B. Elyakov Pacific Institute of Bioorganic Chemistry, and A.V. Zhirmunsky National Scientific Center for Marine Biology have discovered four new steroid substances which target cells of human breast cancer, and colorectal carcinoma.

26 Jun 2020

Molecular & Structural Biology

New strategies can help increase the efficiency of artificial cell reprogramming

UCLA scientists identify new function for histones

Researchers unravel how the body fights off urinary tract infections

Studies show how individual cells maintain their internal clocks

New technology can increase the quality of stem cells used in regenerative medicine

Developing Vaccines and Therapeutics by Exploiting Structure in Spherical Nucleic Acids

CityU develops CRISPR-assisted method to identify RNA-binding proteins in living cells

Researchers discover a protein that protects B cells from stress-induced cell death

Research shows how a protein's small change leads to big trouble for cells

A data-rich atlas of the developing human brain

Study uncovers algorithms and neural circuit mechanisms of escape responses

Scientists discover osmotic stress as stimulator of cellular waste disposal

Biophysicists propose a simple way to observe heart tissue

Researchers provide mechanistic insight into protein co-aggregation in Alzheimer's disease

New steroid compounds from deep-water starfish show anticancer activity

Researchers identify new protein complex that regulates chromosome separation

Researchers identify new molecules to study specific glial cells integral to synapses

Simplified artificial cell brings to light the dynamics of cellular symmetry

Single-cell sequencing method reveals possible evolutionary trajectories of cancer cells

Tiny protein in mitochondria has a big impact on health and longevity, study shows

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

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