Molecular & Structural Biology

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Princeton researchers uncover vital role played by a protein elevated in many cancers

Researchers at Princeton University have successfully recreated a key process involved in cell division in a test tube, uncovering the vital role played by a protein that is elevated in over 25% of all cancers.

14 Jan 2020

New tool could speed up neuroscience research into pheromones

Researchers at Worcester Polytechnic Institute have developed a tool to identify molecular receptors in worms that are involved in sensing pheromones related to mating, an advance that could speed up neuroscience research into pheromones by eliminating months of work.

14 Jan 2020

Study shows how cancer-causing genes promote metastasis

Cancer-promoting genes MYC and TWIST1 co-opt immune system cells to enable cancer cells to spread, but blocking a key step in this process can help prevent the disease from developing.

14 Jan 2020

How SpatialOMx is Delivering New Insights into Disease Research

An interview with Shannon Cornett Ph.D, discussing the use of MALDI-guided spatial molecular analysis for biomarker discovery.

From Bruker Life Sciences Mass Spectrometry 14 Jan 2020

New study sheds light on storage and retrieval of hardwired long-term memory

Storing and retrieving memories is among the most important tasks our intricate brains must perform, yet how that happens at a molecular level remains incompletely understood.

13 Jan 2020

Scientists gain insights into structure and interactions of EGF receptors

Whether a cell grows, divides or dies is controlled among other things by receptors that messenger substances bind to externally.

13 Jan 2020

Researchers discover new cellular player involved in obesity

The prevalence of obesity, a disease considered a serious public health problem, is increasing globally. In Portugal, almost half of the population is overweight and close to one million adults suffer from obesity.

11 Jan 2020

New molecular probe senses the state of proteome in live cells

The folding state of the proteins in live cells often reflect the cell’s general health. Australian scientists have developed a molecular probe that senses the state of the proteome—the entire set of the proteins—by measuring the polarity of the protein environment.

10 Jan 2020

Missing a key protein in the brain can cause autism-like behaviors

Scientists at Rutgers University-Newark have discovered that when a key protein needed to generate new brain cells during prenatal and early childhood development is missing, part of the brain goes haywire - causing an imbalance in its circuitry that can lead to long-term cognitive and movement behaviors characteristic of autism spectrum disorder.

9 Jan 2020

Insect leaf-wounding produces healthier organic fruit

Texas A&M AgriLife Research scientists found benefits of insect leaf-wounding in fruit and vegetable production. Stress responses created in the fruits and vegetables initiated an increase in antioxidant compounds prior to harvest, making them healthier for human consumption.

9 Jan 2020

Research reveals cardiac thin filament structure and function

Researchers at Osaka University used electron cryomicroscopy to image essential cardiac muscle components, known as thin filaments, with unprecedented resolution.

9 Jan 2020

Researchers report first structural model for key enzyme associated with inherited eye diseases

Researchers at the University of New Hampshire have reported the first structural model for a key enzyme, and its activating protein, that can play a role in some genetically inherited eye diseases like retinitis pigmentosa and night blindness.

8 Jan 2020

Scientists map the location of structural proteins in pig ovary for the first time

For the first time, scientists identified and mapped the location of structural proteins in a pig ovary. Ongoing development of an "ink" with these proteins will be used for 3-D printing an artificial (or bio-prosthetic) ovary that could be implanted and allow a woman to have a child.

6 Jan 2020

Discovery of cellular 'hands' could have implications in the fields of cell, developmental biology

The protein, called syndecan-4, combines with fellow cell membrane proteins, called integrins, to form protruding 'hands' that sense the environment outside the cell.

6 Jan 2020

Researchers reveal how antibodies assemble to form a circle for defensive attack

Antibodies are key players in our immune system. These antibodies recognize antigens displayed on foreign cell membranes and thereby recruit attacking forces, called complements.

6 Jan 2020

Novel study on molecular interactions could make it easier to develop new medicines

A first-of-its-kind study on molecular interactions by biomedical engineers in the University of Minnesota's College of Science and Engineering will make it easier and more efficient for scientists to develop new medicines and other therapies for diseases such as cancer, HIV, and autoimmune diseases.

3 Jan 2020

Structure of most lethal toxin produced by C. difficile bacteria identified

Researchers from the University of Maryland School of Medicine and their colleagues have identified the structure of the most lethal toxin produced by certain strains of Clostridium difficile bacteria, a potentially deadly infection associated with the use of antibiotics. The

2 Jan 2020

Early modern humans in southern Africa cooked starchy plants 170 thousand years ago

"The inhabitants of the Border Cave in the Lebombo Mountains on the Kwazulu-Natal/eSwatini border were cooking starchy plants 170 thousand years ago," says Professor Lyn Wadley, a scientist from the Wits Evolutionary Studies Institute at the University of the Witwatersrand, South Africa.

2 Jan 2020

Measuring glycans in samples of antibodies

When Lorna De Leoz invited laboratories to participate in her glycomics study, she hoped for 20 responses. Instead, she was deluged by emails from around the world.

2 Jan 2020

Study reveals key insight into the development of hair bundles

New research reveals a key insight into the development of hair bundles, the intricately complex assemblies in the inner ear responsible for hearing.

2 Jan 2020

Molecular & Structural Biology

Princeton researchers uncover vital role played by a protein elevated in many cancers

New tool could speed up neuroscience research into pheromones

Study shows how cancer-causing genes promote metastasis

How SpatialOMx is Delivering New Insights into Disease Research

New study sheds light on storage and retrieval of hardwired long-term memory

Scientists gain insights into structure and interactions of EGF receptors

Researchers discover new cellular player involved in obesity

New molecular probe senses the state of proteome in live cells

Missing a key protein in the brain can cause autism-like behaviors

Insect leaf-wounding produces healthier organic fruit

Research reveals cardiac thin filament structure and function

Researchers report first structural model for key enzyme associated with inherited eye diseases

Scientists map the location of structural proteins in pig ovary for the first time

Discovery of cellular 'hands' could have implications in the fields of cell, developmental biology

Researchers reveal how antibodies assemble to form a circle for defensive attack

Novel study on molecular interactions could make it easier to develop new medicines

Structure of most lethal toxin produced by C. difficile bacteria identified

Early modern humans in southern Africa cooked starchy plants 170 thousand years ago

Measuring glycans in samples of antibodies

Study reveals key insight into the development of hair bundles

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

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