Molecular & Structural Biology

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Scientists publish structural and functional keys that distinguish two similar transcription factors

Scientists at the Institute for Research in Biomedicine, in collaboration with the Sloan Kettering Institute (New York, US), have published the structural and functional keys that distinguish two very similar transcription factors, namely SMAD2 and SMAD3.

12 Nov 2019

Compound that may help delay onset of Alzheimer’s can be produced in baker’s yeast

Scientists prove that ergothioneine, an important compound that may be used to delay the onset of diseases such as Alzheimer’s and dementia, can be produced in baker’s yeast.

11 Nov 2019

Study shows how glucocorticoid hormones control sugar and fat levels over the course of 24 hours

For the first time, a study led by researchers at Helmholtz Zentrum München and the German Center for Diabetes Research shows how glucocorticoid hormones, such as cortisol, control sugar and fat levels differently during day and night, feeding and fasting, rest and activity, over the course of 24 hours.

10 Nov 2019

Musical pleasure linked to right combination of uncertainty and surprise

Why is it that people find songs such as James Taylor's "Country Roads," UB40's "Red, Red Wine," or The Beatles' "Ob-La-Di, Ob-La-Da" so irresistibly enjoyable? In a study reported in the journal Current Biology on November 7, researchers analyze 80,000 chords in 745 classic U.S. Billboard pop songs--including those three--and find that musical pleasure comes from the right combination of uncertainty and surprise.

8 Nov 2019

Humans can have normal olfaction without typical olfactory bulbs

Our sense of smell depends on the transmission of olfactory information from the nose to the olfactory bulb in the brain through the olfactory nerve. And without olfactory bulbs, smell isn't possible--or so scientists thought.

8 Nov 2019

Understanding Monoclonal Antibody Unfolding and Aggregation

A therapeutic monoclonal antibody and its Fab and Fc fragments were recently investigated using differential scanning fluorimetry, temperature-ramped dynamic light scattering, and turbidity measurements.

From Waters | Wyatt Technology 8 Nov 2019

Researchers join forces to adapt novel genetic tool for zoonotic Chlamydia

The human pathogenic bacterium Chlamydia trachomatis is the most common sexually transmitted bacterial pathogen worldwide.

7 Nov 2019

UVA scientists develop a better way to determine what our genes do

Scientists at the University of Virginia School of Medicine have developed a better way to determine what our genes do – allowing scientists to better probe the genetic causes of diseases and more efficiently determine whether new drugs will act on the intended target exactly as needed.

7 Nov 2019

New study sheds light on how memories are formed

How does the brain translate information from the outside world into something we remember? An international team of researchers working in the Human Brain Project have zoomed in on the neuronal circuits in the striatum, a brain structure involved in memory, behavior and reward learning.

7 Nov 2019

Integrating European life sciences in the area of imaging

The European Commission has officially established Euro-BioImaging - which provides life scientists with open access to a broad range of technologies and resources in biological and biomedical imaging - as a European Research Infrastructure Consortium.

7 Nov 2019

NJIT professor receives Fulbright U.S. Scholar Award, joins circadian clock research project

Casey Diekman, associate professor of mathematics at New Jersey Institute of Technology (NJIT), has been named recipient of a prestigious Fulbright U.S. Scholar Program Award to the United Kingdom in Mathematical Biology.

6 Nov 2019

Using high-resolution X-ray analysis to solve structure of stress proteins from Staphylococcus

Project leader, Head of Structural Biology Lab Konstantin Usachev explains, One of the main factors favoring a microorganism's survival in extreme conditions is preserving ribosomes - a macromolecular complex comprising RNA and proteins.

6 Nov 2019

Scientists discover structure of novel RNA-modifying enzyme

RNA, or ribonucleic acid, is present in the cells of all living beings and required to synthesize proteins. A research team at the University of California, Riverside, has discovered the structure of a novel RNA-modifying enzyme, ZCCHC4, and identified the mechanism that controls how this enzyme recognizes its substrate.

6 Nov 2019

New imaging methods provide unprecedented close-up view of cilia linked to blindness

A new study published today by researchers from Baylor College of Medicine and UT Health's McGovern Medical School in the Proceedings of the National Academy of Sciences reveals an unprecedented close-up view of cilia linked to blindness.

5 Nov 2019

Researchers find genes from 'fossil' virus in human DNA to be active

Genes from a virus that was stitched into the human genome thousands of years ago are active, producing proteins in the human brain and other tissues, according to researchers at the University of Washington School of Medicine and the Laval University School of Medicine in Quebec, Canada.

5 Nov 2019

Scientists capture elusive cancer-related protein in action

Scientists have for the first time seen how the MYC protein, which plays a central role in cancer, binds to a key protein and controls important functions in the cell.

4 Nov 2019

Properties of spider silk proteins could be selectively modified to synthesize novel biomaterials

Spider silk consists of fiber-forming proteins, stored by the spider in a specialized gland. When the spider needs silk, for instance to build a web, it extrudes the silk proteins through a long duct in which they are exposed to specific mechanical and chemical influences and assembled to form silk.

4 Nov 2019

Molecular & Structural Biology

Scientists publish structural and functional keys that distinguish two similar transcription factors

Compound that may help delay onset of Alzheimer’s can be produced in baker’s yeast

Study shows how glucocorticoid hormones control sugar and fat levels over the course of 24 hours

Musical pleasure linked to right combination of uncertainty and surprise

Humans can have normal olfaction without typical olfactory bulbs

Understanding Monoclonal Antibody Unfolding and Aggregation

Researchers join forces to adapt novel genetic tool for zoonotic Chlamydia

UVA scientists develop a better way to determine what our genes do

New study sheds light on how memories are formed

Integrating European life sciences in the area of imaging

NJIT professor receives Fulbright U.S. Scholar Award, joins circadian clock research project

Using high-resolution X-ray analysis to solve structure of stress proteins from Staphylococcus

Scientists discover structure of novel RNA-modifying enzyme

New imaging methods provide unprecedented close-up view of cilia linked to blindness

Researchers find genes from 'fossil' virus in human DNA to be active

Scientists capture elusive cancer-related protein in action

Properties of spider silk proteins could be selectively modified to synthesize novel biomaterials

RCSB Protein Data Bank at Rutgers receives $34.5 million funding

UI scientists are developing new delivery tools for gene editing

Varied diets may be the cause for differences in human and non-human primate saliva

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

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