Molecular & Structural Biology

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Research suggests greater complexity in cellular protein movement

A new imaging technique that makes it possible to match motor proteins with the cargo they carry within a cell is upending a standard view of how cellular traffic reaches the correct destination.

23 Oct 2019

Study uses baker's yeast to show how genes interact to influence a surprising cellular outcome

Most diseases are complex--caused by faults in multiple genes--but studying how combinations of different genetic variants affect cellular traits is challenging.

23 Oct 2019

Study shows how cell competition corrects noisy morphogen gradients during embryogenesis

Tissue patterning is an important process during embryo formation, as well in adult tissue, which ensures that groups of cells are correctly arranged to allow them to function properly.

23 Oct 2019

New research challenges the traditional understanding of cellular sleep

A University of Arizona-led research team challenged the traditional understanding of cellular sleep and discovered new information that could lead to interventions in the aging process.

22 Oct 2019

Study shows how mouse X and Y chromosomes compete with each other to control sex of offspring

The molecular function of genes in mice has a major influence on the sex of their offspring, according to a new discovery that reveals more about the impact of genes on animal fertility.

21 Oct 2019

Columbia researchers capture new detailed images of a temperature-sensing molecule

Columbia University researchers have captured new detailed images of a temperature-sensing molecule in its open, intermediate, and closed states.

21 Oct 2019

Link found between genetic variations and size of the brainstem, other subcortical structures

Researchers have found a link between 48 common genetic variations and the size of the brainstem and other subcortical structures deep within the brain.

21 Oct 2019

SciLifeLab and AstraZeneca establish cryo-EM collaboration to advance biomedicine

The study published in Science Advances reveals the mechanism by which the receptor tyrosine kinase RET can increase neuronal survival in degenerative diseases. To understand the mechanism of this signaling complex, the researchers solved the cryo-EM structure of its extracellular region, employing a new approach for data collection.

21 Oct 2019

Salk scientists receive NIH funding to map brain circuitry for movement

A team of Salk scientists led by Professor Martyn Goulding has been awarded $14.3 million over five years by the National Institutes of Health to create a high-resolution atlas of how the mouse brain generates and controls skilled forelimb movements, such as reaching and grasping.

18 Oct 2019

'Flamenco-style' dancing molecule could form the basis for new longer-lasting sunscreen

A molecule that protects plants from overexposure to harmful sunlight thanks to its flamenco-style twist could form the basis for a new longer-lasting sunscreen, chemists at the University of Warwick have found, in collaboration with colleagues in France and Spain.

18 Oct 2019

Building models to reconstruct evolutionary change more accurately than ever before

Remember domain, kingdom, phylum, class, order, family, genus, species and Darwin's tree of life metaphor we learned about in high school biology? That way of describing living-things lineages is just science's best guess about how genes have mutated and split over time to change things into what they are today.

17 Oct 2019

Scientists unravel how left-right information is integrated to correct organ positioning

Scientists from the Instituto de Neurociencias CSIC-UMH in Alicante, Spain, under the supervision of Professor Angela Nieto, have discovered the molecular mechanism that ensures the right equilibrium needed in left-right signaling cascade during development for the correct leftward positioning of the heart.

17 Oct 2019

Common bug repellent may chemically 'cloak' humans from malaria-carrying mosquitos

Since its invention during the Second World War for soldiers stationed in countries where malaria transmission rates were high, researchers have worked to pinpoint precisely how DEET actually affects mosquitos.

17 Oct 2019

Skin's circadian clock is independent of the eyes or brain, study finds

Squids, octopuses, cuttlefish, amphibians, and chameleon lizards are among the animals that can change the color of their skin in a blink of an eye. They have photoreceptors in their skin that operate independently of their brain. The photoreceptors are part of a family of proteins known as opsins.

16 Oct 2019

Stony Brook-led study reveals how proteome collapse process drives cell death and aging

Cells undergo natural aging and death, processes that impact a multitude of cellular factors. A new Stony Brook University-led study, to be published in PNAS, provides a biophysical model that reveals how damage accumulates in the shapes of cellular proteins with age and is a trigger to death.

16 Oct 2019

Scientists decipher assembly line of glutamate receptors

Rapid communication of neurons in the brain, as well as the ability to learn, fundamentally rely on neurotransmitter receptors located in the contact sites of neurons, the synapses. The most important receptors in the mammalian brain are glutamate receptors of the AMPA-type that generate the electrical signal required for fast communication between neurons.

16 Oct 2019

New technique reveals how the brain responds to light signals received by the retina

In recent decades, scientists have learned a great deal about how different neurons connect and send signals to each other. But it's been difficult to trace the activity of individual nerve fibers known as axons, some of which can extend from the tip of the toe to the head.

15 Oct 2019

Molecular & Structural Biology

Research suggests greater complexity in cellular protein movement

Study uses baker's yeast to show how genes interact to influence a surprising cellular outcome

Study shows how cell competition corrects noisy morphogen gradients during embryogenesis

New research challenges the traditional understanding of cellular sleep

Study shows how mouse X and Y chromosomes compete with each other to control sex of offspring

Columbia researchers capture new detailed images of a temperature-sensing molecule

Link found between genetic variations and size of the brainstem, other subcortical structures

SciLifeLab and AstraZeneca establish cryo-EM collaboration to advance biomedicine

Salk scientists receive NIH funding to map brain circuitry for movement

'Flamenco-style' dancing molecule could form the basis for new longer-lasting sunscreen

Building models to reconstruct evolutionary change more accurately than ever before

Scientists unravel how left-right information is integrated to correct organ positioning

Common bug repellent may chemically 'cloak' humans from malaria-carrying mosquitos

Skin's circadian clock is independent of the eyes or brain, study finds

Stony Brook-led study reveals how proteome collapse process drives cell death and aging

Scientists decipher assembly line of glutamate receptors

New technique reveals how the brain responds to light signals received by the retina

Simpler and direct method for producing lipidated proteins

Study suggesting that CRISPR babies are likely to die early has been retracted

'Tricked' bacteria open door to new antimicrobial therapies

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

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