Molecular & Structural Biology

RSS

Catenane magic: Boosting protein stability and resilience with interlocking rings

This study is led by Prof. Wen-Bin Zhang (College of Chemistry and Molecular Engineering, Peking University & Beijing Academy of Artificial Intelligence) and Dr. Jing Fang (College of Chemistry and Molecular Engineering, Peking University).

29 Dec 2023

Cadmium linked to DNA damage and morphological changes caused by particulate matter

Particulate matter causes health problems for those who inhale the fine droplets and particles, but the chemical composition of the mixture matters-;and can vary widely across space and time.

28 Dec 2023

Neutrophils: Unraveling their multifaceted roles in inflammatory bowel disease and gut microbiota interactions

Research delves into the complex roles of neutrophils in inflammatory bowel disease (IBD), exploring their diverse functions and interactions with the gut microbiota and emphasizing the need for targeted therapies based on these insights.

27 Dec 2023

Research reveals how "forever chemicals" damage DNA at the molecular level

Recent research published in the journal Eco-Environment & Health (Volume 2, 2023) reveals groundbreaking insights into how typical PFAAs accelerate the degradation of DNA.

26 Dec 2023

Fox urine compound effectively repels flies through multisensory activation

Crop damage in agriculture and the transmission of vector-borne diseases by insect pests have become worldwide threat nowadays.

25 Dec 2023

St. Jude researchers crack the code of the β2-adrenergic receptor

Through an international collaboration, scientists at St. Jude Children's Research Hospital leveraged data science, pharmacology and structural information to conduct an atomic-level investigation into how each amino acid in the receptor that binds adrenaline contributes to receptor activity in the presence of this natural ligand.

22 Dec 2023

Shedding new light on the hidden organization of the cytoplasm

Back in 2018, the lab of Christine Mayr, MD, PhD, at Memorial Sloan Kettering Cancer Center (MSK) introduced the world to a key cellular component that had been hiding in plain sight.

21 Dec 2023

St. Jude researchers reveal structure of Parkinson's-linked proteins

Scientists at St. Jude Children's Research Hospital revealed the complex structure of two Parkinson's disease-related proteins, both of which are implicated in late-onset cases.

21 Dec 2023

Clearing the cellular clutter: New insights into how our cells stay healthy

If we don't take out the trash regularly, our homes become unpleasant and even a danger to our health.

20 Dec 2023

TMDU researchers develop novel method to identify protein-protein binding interfaces

Proteins are building blocks of our bodies, but they do not work solo. They form partners to facilitate in different biological processes that keep us going.

20 Dec 2023

Study reveals cytoglobin's pivotal role in cilia movement and organ positioning during development

Study reveals that cytoglobin (cygb2) plays a crucial role in regulating cilia motility and organ laterality during development, highlighting its importance in NO signaling and cilia function.

19 Dec 2023

Novel adaptations and functions of human LINE-1 revealed by structural analysis and inhibition

Martin Taylor, MD, PhD, a physician investigator in the Department of Pathology at Massachusetts General Hospital and an instructor in Pathology at Harvard Medical School, is the lead corresponding author of a new study in Nature, Structural Analysis and Inhibition of Human LINE-1 ORF2 Protein Reveals Novel Adaptations and Functions.

19 Dec 2023

Sirtuin 6: A potential savior for aging cartilage and osteoarthritis

A new research paper was published in Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 15, Issue 23, entitled, "Sirtuin 6 activation rescues the age-related decline in DNA damage repair in primary human chondrocytes."

19 Dec 2023

Study reveals hidden inactive form of p38a protein

p38a protein, a key enzyme in the regulation of various cellular functions, plays a crucial role in some diseases, including cancer, chronic inflammation, and neurodegenerative conditions.

19 Dec 2023

Leaky gut linked to depressive disorders: New insights into microbiota-induced epigenetic changes

A study in the journal Genes highlights how a leaky gut can lead to depressive disorders through changes in gut microbiota-derived metabolites, emphasizing the role of diet, environmental factors, and probiotics in managing these conditions.

18 Dec 2023

Study reveals altered time perception in early Alzheimer's stages, offering potential early diagnostic marker

Study investigates time perception in Alzheimer's disease and its preclinical stage, subjective cognitive decline (SCD), revealing specific alterations in temporal processing that could be early markers of cognitive decline.

18 Dec 2023

Scientists crack the code for targeting cancer's 'death star' protein

Researchers at the Centre for Genomic Regulation in Barcelona, Spain, and the Wellcome Sanger Institute near Cambridge, UK, have comprehensively identified the allosteric control sites found in the protein KRAS.

18 Dec 2023

Deep learning designs high-affinity protein binders for bioactive helical peptides

A new study Dec. 18 in Nature reports an AI-driven advance in biotechnology with implications for drug development, disease detection, and environmental monitoring.

18 Dec 2023

Hemoglobin-like protein plays an important role in the development of the heart, study finds

In a landmark study led by the University of Maryland School of Medicine, researchers discovered for the first time that a certain kind of protein similar to hemoglobin, called cytoglobin, plays an important role in the development of the heart.

15 Dec 2023

Advanced imaging technique reveals the high-resolution structure of cyanobacterial virus

A research team at the Hong Kong University of Science and Technology (HKUST) has outlined the high-resolution structure of a little-known virus, improving our understanding of viral infection, which could pave the way for more accurate predictions of climate change.

14 Dec 2023

Molecular & Structural Biology

Catenane magic: Boosting protein stability and resilience with interlocking rings

Cadmium linked to DNA damage and morphological changes caused by particulate matter

Neutrophils: Unraveling their multifaceted roles in inflammatory bowel disease and gut microbiota interactions

Research reveals how "forever chemicals" damage DNA at the molecular level

Fox urine compound effectively repels flies through multisensory activation

St. Jude researchers crack the code of the β2-adrenergic receptor

Shedding new light on the hidden organization of the cytoplasm

St. Jude researchers reveal structure of Parkinson's-linked proteins

Clearing the cellular clutter: New insights into how our cells stay healthy

TMDU researchers develop novel method to identify protein-protein binding interfaces

Study reveals cytoglobin's pivotal role in cilia movement and organ positioning during development

Novel adaptations and functions of human LINE-1 revealed by structural analysis and inhibition

Sirtuin 6: A potential savior for aging cartilage and osteoarthritis

Study reveals hidden inactive form of p38a protein

Leaky gut linked to depressive disorders: New insights into microbiota-induced epigenetic changes

Study reveals altered time perception in early Alzheimer's stages, offering potential early diagnostic marker

Scientists crack the code for targeting cancer's 'death star' protein

Deep learning designs high-affinity protein binders for bioactive helical peptides

Hemoglobin-like protein plays an important role in the development of the heart, study finds

Advanced imaging technique reveals the high-resolution structure of cyanobacterial virus

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

Latest Life Science News