Molecular & Structural Biology

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Structure of brain networks can change in fundamental and recurring ways over time

The shape and connectivity of brain networks -- discrete areas of the brain that work together to perform complex cognitive tasks -- can change in fundamental and recurring ways over time, according to a study led by Georgia State University.

9 Jul 2019

Researchers capture high-resolution, 3D images of gene-editing enzymes

For the first time, scientists have captured high-resolution, three-dimensional images of an enzyme in the process of precisely cutting DNA strands.

9 Jul 2019

New alliance will focus on the structural visualization of novel druggable sites

PhoreMost has entered into an alliance with CCBT in India for the structural visualization of novel druggable sites across multiple targets.

From PhoreMost 8 Jul 2019

Study sheds light on complex caspase-1-induced cell death mechanisms

Most unnecessary or dangerous cells such as virus-infected cells commit suicide by activating an in-built suicide program.

5 Jul 2019

Using NMR to Study Protein Structure, Dynamics and Mechanisms

Fábio Almeida describes how NMR can be used to elucidate protein structure and how this data can be applied to human disease.

From Bruker BioSpin - NMR, EPR and Imaging 4 Jul 2019

Study reveals first complete wiring diagram of an animal's nervous system

In a study published online today in Nature, researchers at Albert Einstein College of Medicine describe the first complete wiring diagram of the nervous system of an animal, the roundworm Caenorhabditis elegans, used by scientists worldwide as a model organism.

4 Jul 2019

Researchers use artificial intelligence to predict molecular classification of colorectal cancer

Treating physicians need information about the molecular subtype of the tumor if they are to provide targeted therapy for colorectal carcinoma.

4 Jul 2019

HER2-positive breast cancer may be treated with imprinted nanospheres

A particularly aggressive, metastasizing form of cancer, HER2-positive breast cancer, may be treated with nanoscopic particles “imprinted” with specific binding sites for the receptor molecule HER2.

4 Jul 2019

Researchers completely eliminate all traces of HIV from infected mice

For the first time, researchers have successfully removed HIV-1 DNA from the genomes of living animals, a critical step towards a potential cure for the disease.

4 Jul 2019

Neuroscientists control visual behavior of a mouse with single-cell precision

For the first time, a team of neuroscientists from Columbia University have controlled a visual behavior of a mouse by activating a few neurons in its visual cortex.

4 Jul 2019

Unique method to study proteins could open new doors for medicinal research

Researchers at Chalmers University of Technology, Sweden, have developed a unique method for studying proteins which could open new doors for medicinal research.

3 Jul 2019

Scientists discover a new way to kill drug-resistant parasites

Over one billion people, including 880 million children, are infected with intestinal nematode worms, such as roundworms, hookworms and tapeworms, according to the World Health Organization.

2 Jul 2019

'Scissors' component of CRISPR/Cas9 sometimes gets stuck

In biotech these days, CRISPR/Cas9 is a hot topic, because of its utility as a precise gene editing tool. Before humans repurposed it, CRISPR/Cas9 was a sort of internal immune system bacteria use to defend themselves against phages, or viruses that infect bacteria, by slicing up the phages' DNA.

2 Jul 2019

Study reveals time taken for DNA repair after chemotherapy

In the time it takes for an Amazon Prime delivery to arrive, cells damaged by chemotherapy can almost completely fix their most important DNA. That is the case in the livers of mice at least, according to a new study.

2 Jul 2019

Scientists identify new genetic mutation behind serious skull disorder

A collaboration led by scientists at Oregon State University, the University of Oxford in the United Kingdom and Erasmus University in The Netherlands has identified a new genetic mutation behind the premature fusing of the bony plates that make up the skull.

2 Jul 2019

Artificial DNA can help release active ingredients from drugs in sequence

A drug with three active ingredients that are released in sequence at specific times: Thanks to the work of a team at the Technical University of Munich, what was once a pharmacologist's dream is now much closer to reality.

29 Jun 2019

Scientists discover neurons for 3D vision in insect brains

Scientists at Newcastle University, UK have discovered neurons in insect brains that compute 3D distance and direction. Understanding these could help vision in robots.

29 Jun 2019

White matter structure in the brain reflects individual differences in music sensitivity

The white matter structure in the brain reflects music sensitivity, according to a study by the research group on Cognition and Brain Plasticity of the Institute of Neurosciences of the University of Barcelona and the Bellvitge Biomedical Research Institute.

29 Jun 2019

Cutting-edge electron microscopy reveals first structures of a lipid-flippase

Using cutting-edge electron microscopy, researchers from Aarhus University have determined the first structures of a lipid-flippase.

29 Jun 2019

Cells in humans are affected by thirdhand smoke, study shows

Thirdhand smoke can damage epithelial cells in the respiratory system by stressing cells and causing them to fight for survival, a research team led by scientists at the University of California, Riverside, has found. The finding could assist physicians treating patients exposed to thirdhand smoke.

28 Jun 2019