Molecular & Structural Biology

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Microglia show distinct responses under inflammatory conditions

The NorLux Neuro-Oncology Laboratory at LIH's Department of Oncology conducts research on brain diseases, with a special emphasis on glioma biology, drug resistance and systems approaches.

26 Nov 2018

Researchers attempt to create world's first genetically edited babies

The researchers have used CRISPR to edit the genes of IVF embryos in a controversial attempt to create offspring that are resistant to disease.

26 Nov 2018

Bone marrow-derived fibroblasts shown to promote breast cancer growth

A new study has revealed that breast cancer cells recruit bone marrow-derived fibroblasts to enhance their growth.

23 Nov 2018

Scientists transform protein interaction studies

A team of leading academics has significantly advanced a method for studying the interactions of proteins, which will transform research in this area.

23 Nov 2018

Researchers discover new mitochondrial mechanism

Researchers at the University of Freiburg have discovered a mechanism within cells that enables proteins to be delivered into the mitochondria.

22 Nov 2018

Researchers provide new insights into regulation of important intracellular messenger molecule

The team of prof. Joris Messens at the VIB-VUB Center for Structural Biology has provided new insights into the regulation of an important intracellular messenger molecule, hydrogen peroxide (H2O2), whose dysregulation has been linked to the development of several diseases, including cancer.

22 Nov 2018

UVA researchers make unexpected discovery about irreplaceable nerve cells

Meticulous new research from the University of Virginia School of Medicine has changed a well-accepted scientific belief about neurons, the vital nerve cells that allow us to experience the world and record those experiences as memories in our brains.

22 Nov 2018

Discovery of new gene could lead to better understanding of human susceptibility to chemicals

The discovery of a new gene in zebrafish could lead to a better understanding of how exposure to chemicals leads to disease in humans, according to a new Oregon State University study.

22 Nov 2018

Scientists uncover genomic keys to successful evolution of vertebrates

One of the most important results of this work consists of understanding how the genomic duplications that occurred in the origin of the vertebrates contributed to diversifying gene function.

22 Nov 2018

Sugar supplement shown to slow tumor growth and enhance chemotherapy

Mannose, a type of sugar, has been shown to slow tumor growth and enhance chemotherapy in mouse models of certain cancers.

21 Nov 2018

Starved ticks try harder to find hosts

Ticks are hardy little brutes that can go as long as a year without a meal. Now scientists at the University of Cincinnati say the hungrier ticks are, the harder they try to find you or other hosts. The findings could have implications for the spread of tick-borne disease such as Lyme or Rocky Mountain Spotted Fever.

21 Nov 2018

Study explores how the moving brain processes visual information

What we see is not only determined by what is really there, but also depends on whether we are paying attention, whether we are moving, excited or interested.

21 Nov 2018

Researchers shed light on molecular mechanisms of heart valvular disease

About three per cent of the world's population is affected by valvular heart diseases. It is also the most common cause of heart surgery, as no drug-based treatment is available.

20 Nov 2018

DNA vaccine reduces levels of toxic proteins in Alzheimer’s model

Researchers have developed a new DNA vaccine that reduces the build-up of the toxic proteins associated with Alzheimer’s disease.

20 Nov 2018

Receptor structure could be key to developing new osteoporosis drugs

Researchers at the University of Zurich have determined the three-dimensional structure of a receptor that controls the release of calcium from bones. The receptor is now one of the main candidates for developing new drugs to treat osteoporosis.

19 Nov 2018

RNAi therapy shown to alleviate preeclampsia in animal model

Researcher have used a small interfering RNA (siRNA) to reduce preeclampsia symptoms in an animal model. The approach could provide a new way of treating preeclampsia in humans.

19 Nov 2018

Artificial bone-like substance mimics the way real bone grows at atomic level

Researchers from Chalmers University of Technology, Sweden, have discovered how our bones grow at an atomic level, showing how an unstructured mass orders itself into a perfectly arranged bone structure.

19 Nov 2018

Automating Data Capture and Image Analysis in Continuous Experiments

An interview with Lindy O’Clair, discussing the challenges of studying neuronal systems over time, and the development of an automated platform by Sartorius.

From Sartorius 19 Nov 2018

Harvard researchers use echidna forelimb model to shed light on mammal evolution

These days, mammals can use their forelimbs to swim, jump, fly, climb, dig and just about everything in between, but the question of how all that diversity evolved has remained a vexing one for scientists.

18 Nov 2018

New method to analyze cell membrane complexes could revolutionize the way we study diseases

Researchers have developed a new technique to analyze cell membrane proteins in situ which could revolutionize the way in which we study diseases, such as cancer, metabolic and heart diseases.

17 Nov 2018