Molecular & Structural Biology

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Scientists map 3D structure of kappa opioid receptor

Opioids remain the most potent and effective pain relievers in medicine, but they're also among the most addictive drugs that can halt a person's ability to breathe during an overdose -; which can be deadly.

27 Jul 2023

New protein-based nano-switches could lead to faster, more accurate diagnostic tests

QUT researchers have developed a new approach for designing molecular ON-OFF switches based on proteins which can be used in a multitude of biotechnological, biomedical and bioengineering applications.

27 Jul 2023

Diagnosis of rare inherited metabolic condition in a Sumatran orangutan

Researchers from Indiana University School of Medicine have diagnosed a Sumatran Orangutan at the Indianapolis Zoo with a rare genetic disease called Alkaptonuria.

27 Jul 2023

Study identifies specific genetic variants that affect the skeletal form and ties a major evolutionary facet of human anatomical change to pathogenesis

Researchers evaluate imaging information and characterize skeletal proportions to assess the genetic root of these traits and their connections to each other.

26 Jul 2023

Cervical fibroblasts in cervical insufficiency patients show impaired responses to progesterone

The study described in Scientific Reports highlights an impaired response to the hormone progesterone (P4) in cervical fibroblasts from patients with refractory cervical insufficiency (CI).

26 Jul 2023

Study offers a comprehensive analysis of bacterial and fungal alterations in COVID-19

Researchers use nanopore sequencing to determine the fungal and bacterial microbiota in the lungs of COVID-19 and non-COVID-19 patients.

24 Jul 2023

Researchers discover how ribosomes regulate protein production

The human body consists of numerous trillions of cells, and 60 percent of the energy used within a cell is dedicated to a specific molecular machine.

21 Jul 2023

BUB1 protein and its kinase activity may regulate EGFR activation

A new research paper was published in Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 15, Issue 13, entitled, "Budding uninhibited by benzimidazoles-1 (BUB1) regulates EGFR signaling by reducing EGFR internalization."

18 Jul 2023

DNA origami could be used to create customized virus-like particles

Bioengineers have found a way to program the size and shape of virus particles by combining viral protein building blocks and templates made from DNA.

17 Jul 2023

Griffith University researchers develop new method to control virus assembly

Griffith University researchers have played a key role in using DNA 'origami' templates to control the way viruses are assembled.

17 Jul 2023

Unveiling the key defender: PLSCR1 identified as a potent anti-SARS-CoV-2 factor in COVID-19 immunity

Researchers identified the anti-SARS-CoV-2 function of phospholipid scramblase 1 (PLSCR1).

14 Jul 2023

Exploring the relationship between epigenetic aging and gut microbiome composition in physically fit men and women

Researchers investigate the relationship between the gut microbiome, physical fitness, and epigenetic aging in physically fit individuals.

14 Jul 2023

Cryo-EM reveals structure of key enzyme involved in protein production

Transfer RNAs (tRNAs) are among the most common types of RNA in a cell and are indispensable for protein production in all known organisms.

13 Jul 2023

Investigating the role of T-cell immunity in long COVID

Researchers investigates the persistence of symptoms and the immune response in patients recovering from COVID-19.

13 Jul 2023

Scientists track nanoscale processes of CRISPR-Cas complexes

Scientists at Leipzig University, in collaboration with colleagues at Vilnius University in Lithuania, have developed a new method to measure the smallest twists and torques of molecules within milliseconds.

12 Jul 2023

Study unveils an astounding array of unexplored protein folds in nature

A groundbreaking study has shed new light on the astonishing diversity of protein structures and their folds in nature.

12 Jul 2023

Novel protein modifies the cellular machinery responsible for producing cellulose in plant cells

Cellulose -; an integral component of plant cell walls -; is an important source of food, paper, textiles and biofuels, but how its creation is regulated within plant cells has remained unclear.

11 Jul 2023

New study shows circulating anti-insulin CD4 T cells reflect progression of anti-islet immunity

In a recent study published in Science Translational Medicine, researchers profile antigen-specific helper clusters of differentiation 4-positive (CD4+) T-lymphocytes to determine anti-islet autoimmunity among mice and humans.

9 Jul 2023

How B-cells and androgens contribute to the development of PCOS

Researchers evaluate the role of B-cell frequencies in the pathogenesis of polycystic ovary syndrome.

9 Jul 2023

Cryo-EM helps decode the molecular architecture of a neural transport protein

Using Cryo-EM, a powerful microscopy technique, researchers at IISc and collaborators have decoded the molecular architecture of a transporter protein controlling the movement of a key neurotransmitter.

6 Jul 2023

Molecular & Structural Biology

Scientists map 3D structure of kappa opioid receptor

New protein-based nano-switches could lead to faster, more accurate diagnostic tests

Diagnosis of rare inherited metabolic condition in a Sumatran orangutan

Study identifies specific genetic variants that affect the skeletal form and ties a major evolutionary facet of human anatomical change to pathogenesis

Cervical fibroblasts in cervical insufficiency patients show impaired responses to progesterone

Study offers a comprehensive analysis of bacterial and fungal alterations in COVID-19

Researchers discover how ribosomes regulate protein production

BUB1 protein and its kinase activity may regulate EGFR activation

DNA origami could be used to create customized virus-like particles

Griffith University researchers develop new method to control virus assembly

Unveiling the key defender: PLSCR1 identified as a potent anti-SARS-CoV-2 factor in COVID-19 immunity

Exploring the relationship between epigenetic aging and gut microbiome composition in physically fit men and women

Cryo-EM reveals structure of key enzyme involved in protein production

Investigating the role of T-cell immunity in long COVID

Scientists track nanoscale processes of CRISPR-Cas complexes

Study unveils an astounding array of unexplored protein folds in nature

Novel protein modifies the cellular machinery responsible for producing cellulose in plant cells

New study shows circulating anti-insulin CD4 T cells reflect progression of anti-islet immunity

How B-cells and androgens contribute to the development of PCOS

Cryo-EM helps decode the molecular architecture of a neural transport protein

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

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