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Tirzepatide outperforms insulin in controlling diabetes and promoting weight loss in clinical trials

Tirzepatide, a once-weekly dual agonist, outperforms long-acting insulin in reducing HbA1c, body weight, and improving cardiovascular markers in Type 2 diabetes patients.

2 Sep 2024

Is semaglutide use during breastfeeding safe?

Researchers found no detectable levels of semaglutide in breast milk, suggesting minimal risk to breastfed infants, but highlighted the need for monitoring maternal nutrition and milk production.

2 Sep 2024

Evening versus morning dosing of antihypertensive medications provides no added benefits

In two trials, one in frail elderly patients, evening administration of blood pressure (BP)-lowering medications had no clinical benefits over morning administration, according to late-breaking research presented in a Hot Line session today at ESC Congress 2024.

1 Sep 2024

Intranasal vaccine shows broad SARS-CoV-2 variant protection

Study demonstrates that a single-dose intranasal live-attenuated vaccine, CDO-7N-1, provides broad protection against SARS-CoV-2 and its variants by inducing potent immune responses, including neutralizing antibodies and T-cell activity, in animal models.

1 Sep 2024

Timing of blood pressure medication administration does not affect outcomes

Evening administration of blood pressure (BP)-lowering medications did not reduce the risk of cardiovascular events or death compared with morning administration, according to late-breaking research presented in a Hot Line session today at ESC Congress 2024.

1 Sep 2024

Low-dose triple-pill combination outperforms standard care for blood pressure control in Nigerian adults

A low-dose triple single-pill combination-based protocol achieved better blood pressure (BP) control than a standard-care protocol in Black African Nigerian adults with uncontrolled hypertension, according to late-breaking research presented in a Hot Line session today at ESC Congress 2024.

1 Sep 2024

Research suggests flexible approach to antiplatelet management after drug-eluting stent implantation

Among patients undergoing non-cardiac surgery more than 1 year after coronary drug-eluting stent (DES) implantation, there was no difference with respect to ischaemic outcomes or major bleeding between perioperative aspirin monotherapy and receiving no antiplatelet therapy, according to late-breaking research presented in a Hot Line session today at ESC Congress 2024.

1 Sep 2024

Semaglutide cuts death rates from cardiovascular disease and COVID-19

Patients taking semaglutide injections are less likely to die of any cause, including from cardiovascular disease and infections like COVID-19, an international study led by researchers from Brigham and Women's Hospital, a founding member of the Mass General Brigham healthcare system, finds.

30 Aug 2024

Semaglutide's impact on cardiovascular health expands beyond weight loss

Semaglutide, the popular anti-obesity medication originally developed to treat diabetes, continues to show cardiovascular benefits beyond weight loss, including reducing risk of death, reducing serious COVID-19 related events and improving heart failure (HF) symptoms, according to six new substudies published in JACC, the flagship journal of the American College of Cardiology.

30 Aug 2024

Major surgery complications unaffected by use of renin-angiotensin system inhibitors

There was no difference in major post-operative complications in patients who continued vs. stopped renin-angiotensin system inhibitors (RASIs) before non-cardiac surgery, according to late-breaking research presented in a Hot Line session today at ESC Congress 2024.

30 Aug 2024

Semaglutide lowers COVID-19-related deaths in cardiovascular patients with obesity

Semaglutide, the popular anti-obesity drug, reduced the rates of COVID-19-related adverse events, including death, in those who had overweight or obesity and established cardiovascular disease without diabetes, according to a new study published in JACC, the flagship journal of the American College of Cardiology.

30 Aug 2024

Research highlights media misrepresentation of COVID-19 drug efficacy

A new study from researchers at Wake Forest University School of Medicine is shedding light on how scientific evidence and the uncertainty surrounding three unproven therapeutics were portrayed by the U.S. news media during the early days of the COVID-19 pandemic.

30 Aug 2024

The Arctic Sea revealed as a potential treasure trove for new medicines

Researchers discovered new antivirulence and antibacterial compounds from Arctic marine actinobacteria, offering potential solutions to combat antibiotic-resistant E. coli infections.

30 Aug 2024

Study reveals neural processes behind morphine's pain relief

In a study published in Science, researchers at Karolinska Institutet describe the neural processes behind how morphine relieves pain. This is valuable knowledge because the drug has such serious side effects.

29 Aug 2024

Study shows benefits of taking misoprostol at home during medical abortions after 12 weeks

Pregnant people who took the first dose of misoprostol (a pill given as part of the procedure for medical abortions) at home had a 71% chance of completing their care in hospital within 9 hours with no overnight stay when having an abortion after 12 weeks of pregnancy, compared to 46% of those who took the first dose of misoprostol at hospital, finds a randomized controlled trial published in The Lancet.

29 Aug 2024

Exploring the role of suvorexant in reducing delirium among older adults

Delirium is a sudden onset and temporary state of disturbed consciousness or cognition, occurring due to underlying medical issues like fever or alcohol withdrawal.

29 Aug 2024

Tirzepatide beats semaglutide in lowering diabetes risk and cardiovascular events in obesity patients

A study published in eClinicalMedicine found that tirzepatide outperforms semaglutide in reducing the risk of type 2 diabetes and major cardiovascular events among individuals with obesity, with or without existing diabetes, while also achieving greater weight loss.

28 Aug 2024

SGLT-2 inhibitors show potential in preventing dementia in diabetes patients

Sodium-glucose cotransporter-2 (SGLT-2) inhibitors used to treat type 2 diabetes might prevent dementia, providing greater benefits with longer treatment, suggests a large study from Korea published by The BMJ today.

28 Aug 2024

How the 'Pink Tax' inflates prices on women's personal care products

Study reveals how gender-based pricing in personal care products, known as the Pink Tax, burdens women financially through strategic marketing tactics, often unrelated to actual production costs.

28 Aug 2024

Myocarditis risks linked to COVID-19 vaccination explained

Study examined myocarditis risks linked to COVID-19 mRNA vaccination, COVID-19 infection, and other causes. It found increased myocarditis incidence after vaccination but significantly lower mortality and hospitalization rates compared to myocarditis from other causes.

28 Aug 2024

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Pharmaceutical News

Tirzepatide outperforms insulin in controlling diabetes and promoting weight loss in clinical trials

Is semaglutide use during breastfeeding safe?

Evening versus morning dosing of antihypertensive medications provides no added benefits

Intranasal vaccine shows broad SARS-CoV-2 variant protection

Timing of blood pressure medication administration does not affect outcomes

Low-dose triple-pill combination outperforms standard care for blood pressure control in Nigerian adults

Research suggests flexible approach to antiplatelet management after drug-eluting stent implantation

Semaglutide cuts death rates from cardiovascular disease and COVID-19

Semaglutide's impact on cardiovascular health expands beyond weight loss

Major surgery complications unaffected by use of renin-angiotensin system inhibitors

Semaglutide lowers COVID-19-related deaths in cardiovascular patients with obesity

Research highlights media misrepresentation of COVID-19 drug efficacy

The Arctic Sea revealed as a potential treasure trove for new medicines

Study reveals neural processes behind morphine's pain relief

Study shows benefits of taking misoprostol at home during medical abortions after 12 weeks

Exploring the role of suvorexant in reducing delirium among older adults

Tirzepatide beats semaglutide in lowering diabetes risk and cardiovascular events in obesity patients

SGLT-2 inhibitors show potential in preventing dementia in diabetes patients

How the 'Pink Tax' inflates prices on women's personal care products

Myocarditis risks linked to COVID-19 vaccination explained

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