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FDA grants accelerated approval for first engineered T cell therapy to treat adults with synovial sarcoma

The U.S. Food and Drug Administration (FDA) has granted accelerated approval for the immunotherapy afamitresgene autoleuecel (Tecelra®, also known as afami-cel) for the treatment of adults with a rare soft tissue cancer called synovial sarcoma.

2 Aug 2024

Researchers identify strategy to design safer opioids

Opioid medications offer people relief from debilitating pain, but these drugs come with dangers: the risk for addiction, miserable withdrawal symptoms and the potential for fatal overdose.

2 Aug 2024

Triptolide-based treatment prolongs symptom-free survival in preclinical medulloblastoma models

A drug that was developed to treat pancreatic cancer has now been shown to increase symptom-free survival in preclinical medulloblastoma models – all without showing signs of toxicity.

1 Aug 2024

Groundbreaking method dmSLAY improves antimicrobial peptide effectiveness and safety

Researchers developed a high-throughput method, dmSLAY, to assess thousands of AMP variants, combining it with machine learning to enhance membrane selectivity and reduce toxicity.

1 Aug 2024

Aspirin may lower colorectal cancer risk for people with unhealthy lifestyles

Regular aspirin may help lower risk of colorectal cancer in people with greater lifestyle-related risk factors for the disease, according to a study led by researchers at Mass General Brigham.

1 Aug 2024

Anticancer drugs show promise in reducing Alzheimer's dementia risk

Study finds anticancer drugs, specifically antimetabolites and molecular targeted therapies, may reduce the risk of Alzheimer's type dementia but not vascular dementia.

1 Aug 2024

FDA clears UAB startup's TIX100 for clinical trials

The University of Alabama at Birmingham startup TIXiMED, Inc., has obtained clearance from the United States Food and Drug Administration to proceed to clinical trials under an Investigational New Drug for TIX100, its novel oral Type 1 diabetes drug.

31 Jul 2024

Commonly used anesthetic drug can restore the function of ion channel linked to epilepsy

Mutated variants of a particular ion channel cause difficult-to-treat epilepsy. A study published in the journal Nature now shows that a commonly used anesthetic drug, propofol, can restore the function of this ion channel.

31 Jul 2024

Propofol shows potential for treating epilepsy and neurological disorders

The general anesthetic propofol may hold the keys to developing new treatment strategies for epilepsy and other neurological disorders, according to a study led by researchers at Weill Cornell Medicine and Linköping University in Sweden.

31 Jul 2024

Study reveals common off-label dosing of direct oral anticoagulants

Millions of Americans take anticoagulants, commonly known as blood thinners. These medications work to prevent blood clots that cause heart attack and stroke.

31 Jul 2024

Sapio Sciences and Zifo announce strategic partnership

Sapio Sciences, the science-aware™ lab informatics platform, and Zifo, the leading scientific informatics services company, today announced a strategic partnership to bring best-in-class laboratory information management solutions to customers across the biotech, clinical diagnostics, and pharmaceutical industries.

From Sapio Sciences 31 Jul 2024

Weight loss guaranteed! But what impact on your diet? A review of GLP-1 and GIP/GLP-1 interventions

Researchers reviewed studies on dietary impacts of GLP-1 and GIP/GLP-1 receptor agonists in obesity and T2D patients, finding significant caloric reduction but limited evaluation of dietary composition.

29 Jul 2024

FDA-approved iron-chelating drug could provide a novel way to attack ovarian tumors

An iron-binding drug that is already approved for treatment of other diseases could provide a novel way to attack ovarian tumors, according to a new study led by Weill Cornell Medicine researchers.

29 Jul 2024

Semaglutide may reduce smoking risks for diabetes patients

Semaglutide shows promise in reducing tobacco use disorder-related health encounters in patients with type 2 diabetes, but further clinical trials are needed to confirm its efficacy.

29 Jul 2024

Study identifies non-statin cholesterol drugs with potential to lower liver cancer risk

Past studies have suggested that taking cholesterol-lowering statin drugs may lower individuals' risk of developing liver cancer.

29 Jul 2024

Pharmacist cautions against self-medicating with ozempic for dementia risk reduction

“According to the latest figures released by the NHS, dementia diagnosis is at a record high in England.

29 Jul 2024

GLP-1-based polyagonists: A promising weight loss alternative to bariatric surgery

Researchers highlight the unprecedented success of GLP-1-based multi-receptor drugs in achieving substantial weight loss and improved health outcomes, potentially replacing bariatric surgery for obesity treatment.

28 Jul 2024

Experimental cancer drug may help clear HIV from infected cells in the brain

An experimental drug originally developed to treat cancer may help clear HIV from infected cells in the brain, according to a new Tulane University study.

25 Jul 2024

Study finds flurbiprofen ester effective for pain relief during transvaginal 4D hysterosalpingography

Announcing a new article publication for BIO Integration journal. The purpose of this study was to determine the analgesic effect of a flurbiprofen ester injection via continuous intravenous drip during transvaginal 4-dimensional hysterosalpingography (TVS 4D-HyCoSy).

25 Jul 2024

Experimental cancer drug could make thinking easier for individuals with Rett syndrome

An experimental cancer drug could make thinking easier for individuals with Rett syndrome, a rare disorder linked to autism, according to new research from the University of California San Diego - a discovery that could lead to therapies for patients with other neurological conditions.

25 Jul 2024

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Pharmaceutical News

FDA grants accelerated approval for first engineered T cell therapy to treat adults with synovial sarcoma

Researchers identify strategy to design safer opioids

Triptolide-based treatment prolongs symptom-free survival in preclinical medulloblastoma models

Groundbreaking method dmSLAY improves antimicrobial peptide effectiveness and safety

Aspirin may lower colorectal cancer risk for people with unhealthy lifestyles

Anticancer drugs show promise in reducing Alzheimer's dementia risk

FDA clears UAB startup's TIX100 for clinical trials

Commonly used anesthetic drug can restore the function of ion channel linked to epilepsy

Propofol shows potential for treating epilepsy and neurological disorders

Study reveals common off-label dosing of direct oral anticoagulants

Sapio Sciences and Zifo announce strategic partnership

Weight loss guaranteed! But what impact on your diet? A review of GLP-1 and GIP/GLP-1 interventions

FDA-approved iron-chelating drug could provide a novel way to attack ovarian tumors

Semaglutide may reduce smoking risks for diabetes patients

Study identifies non-statin cholesterol drugs with potential to lower liver cancer risk

Pharmacist cautions against self-medicating with ozempic for dementia risk reduction

GLP-1-based polyagonists: A promising weight loss alternative to bariatric surgery

Experimental cancer drug may help clear HIV from infected cells in the brain

Study finds flurbiprofen ester effective for pain relief during transvaginal 4D hysterosalpingography

Experimental cancer drug could make thinking easier for individuals with Rett syndrome

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