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Opioid overdose deaths may be reduced by increasing access to prescription opioid painkillers

Increasing access to prescription opioid painkillers may reduce opioid overdose deaths in the United States, according to a Rutgers study.

27 Jun 2023

mRNA rabies vaccine induces durable immune response in macaques

Novel mRNA vaccine for rabies shows enhanced immune response with higher antibody levels and improved cross-neutralization, indicating potential for a broadly protective vaccine against related lyssavirus strains.

26 Jun 2023

Metformin linked to lower mortality in ICU patients with diabetes and heart failure

Announcing a new article publication for Cardiovascular Innovations and Applications journal. Patients receiving intensive care often have diabetes mellitus (DM) together with chronic heart failure (CHF). In these patients, the use of metformin in intensive care is controversial.

26 Jun 2023

World-renowned researcher receives top award for contributions to clinical psychopharmacology

Dennis Charney, MD, the Anne and Joel Ehrenkranz Dean of the Icahn School of Medicine at Mount Sinai and President for Academic Affairs of the Mount Sinai Health System, has received the prestigious Donald Klein Lifetime Achievement Award from the American Society for Clinical Psychopharmacology (ASCP).

26 Jun 2023

Higher doses of oral semaglutide effective in lowering blood sugar and promoting weight loss

Diabetes is a progressive disease that affects one's ability to control blood sugar levels. For many patients, the condition becomes more severe over time and blood sugar levels grow more difficult to manage.

26 Jun 2023

Experts release new guidelines for safe opioid deprescribing in Australia

Australian and international experts have released 11 recommendations on when, how, and in what situation it may be appropriate for clinicians to reduce opioid use, by placing the patient at the center of the equation.

25 Jun 2023

Plant based compound peruvoside may be able to prevent up to 12 medically important viruses

Peruvoside, a plant-based compound that is commonly used to treat heart failure, has been discovered to be able to prevent up to 12 medically important viruses, all originating from different virus families.

22 Jun 2023

Study reveals how metformin interacts with the liver and gut to reduce circulating glucose levels

There are still many enigmas about the mechanism of action of metformin, the most prescribed drug to treat diabetes mellitus, also known as type 2 diabetes.

22 Jun 2023

Tranexamic acid use linked to decreased incidence of heterotopic ossification after elbow trauma surgery

For patients undergoing surgery for elbow trauma, treatment with the hemostatic drug tranexamic acid (TXA) is associated with a decreased incidence of heterotopic ossification (HO) – a common complication of abnormal bone formation, reports a study in The Journal of Bone & Joint Surgery.

22 Jun 2023

Feeling high associated with improved symptom relief but increased negative side effects in medical cannabis patients

In a new study titled, "Understanding Feeling 'High' and Its Role in Medical Cannabis Patient Outcomes," published in the journal, Frontiers in Pharmacology, researchers at The University of New Mexico, in collaboration with Releaf App™ found that patients who reported feeling "High" experienced 7.7% greater symptom relief and an increase in reporting of positive side effects such as "Relaxed" and "Peaceful."

22 Jun 2023

Do Panax notoginseng saponins (Xuesaitong soft capsules) improve function in patients with ischemic stroke?

Researchers examined the effectiveness and safety of using Panax notoginseng saponins for ischemic stroke in adults.

22 Jun 2023

Repurposing cancer drugs for malaria treatment

With malaria becoming increasingly drug-resistant, a team of UCF researchers is looking to use cancer drugs to accelerate the discovery of new life-saving therapies for the disease.

21 Jun 2023

Repurposed drug effective at inhibiting a protein kinase linked to cardiac arrhythmias

Ruxolitinib, a drug that is already approved by the U.S. Food and Drug Administration (FDA) for treating certain cancers and skin conditions, is effective at inhibiting CaMKII, a protein kinase linked to cardiac arrhythmias.

21 Jun 2023

Ketone supplements used by some athletes may worsen performance

Kinesiologists at McMaster University have found ketone supplements, used by some athletes hoping to cross the finish line faster, may in fact worsen performance.

21 Jun 2023

Hypertension drug shown to prevent post-traumatic headaches

A study led by VA Puget Sound Health Care System researchers has shown that prazosin, a drug used to treat high blood pressure, can prevent posttraumatic headaches.

21 Jun 2023

Study investigates whether metformin mitigates androgen deprivation therapy-related metabolic syndrome

A new research paper was published in Oncotarget's Volume 14 on June 19, 2023, entitled, "Utilizing metformin to prevent metabolic syndrome due to androgen deprivation therapy (ADT): a randomized phase II study of metformin in non-diabetic men initiating ADT for advanced prostate cancer."

21 Jun 2023

Xylazine can exacerbate the life-threatening effects of opioids, rat study shows

A new study in rats suggests that xylazine, the active ingredient in a non-opioid veterinary tranquilizer not approved for human use, can worsen the life-threatening effects of opioids.

21 Jun 2023

Battle against RSV: Computational design paves way for new polyvalent vaccine

Research focuses on the design of a multi-epitope polyvalent vaccine against Human Respiratory Syncytial Virus (RSV), a leading cause of lower respiratory tract infections. The study utilizes computational methods and immunoinformatics tools to predict potential vaccine candidates and their interactions with Toll-like receptors (TLRs).

19 Jun 2023

Comparing the cost-effectiveness of SGLT2i versus mineralocorticoid antagonists

Announcing a new article publication for Cardiovascular Innovations and Applications journal. Sodium-glucose cotransporter 2 inhibitors (SGLT2i) are approved for heart failure with reduced ejection fraction (HFrEF).

19 Jun 2023

Smart drugs fall short as cognitive function enhancers

A recent Science Advances study investigated the effectiveness of three popular smart drugs, namely, modafinil (MOD), methylphenidate (MPH), and dextroamphetamine (DEX), against the difficulty of real-life daily tasks, i.e., the 0-1 knapsack optimization problem (“knapsack task”). A knapsack task is basically a combinatorial optimization task, the class of NP-time challenging problems.

18 Jun 2023

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Pharmaceutical News

Opioid overdose deaths may be reduced by increasing access to prescription opioid painkillers

mRNA rabies vaccine induces durable immune response in macaques

Metformin linked to lower mortality in ICU patients with diabetes and heart failure

World-renowned researcher receives top award for contributions to clinical psychopharmacology

Higher doses of oral semaglutide effective in lowering blood sugar and promoting weight loss

Experts release new guidelines for safe opioid deprescribing in Australia

Plant based compound peruvoside may be able to prevent up to 12 medically important viruses

Study reveals how metformin interacts with the liver and gut to reduce circulating glucose levels

Tranexamic acid use linked to decreased incidence of heterotopic ossification after elbow trauma surgery

Feeling high associated with improved symptom relief but increased negative side effects in medical cannabis patients

Do Panax notoginseng saponins (Xuesaitong soft capsules) improve function in patients with ischemic stroke?

Repurposing cancer drugs for malaria treatment

Repurposed drug effective at inhibiting a protein kinase linked to cardiac arrhythmias

Ketone supplements used by some athletes may worsen performance

Hypertension drug shown to prevent post-traumatic headaches

Study investigates whether metformin mitigates androgen deprivation therapy-related metabolic syndrome

Xylazine can exacerbate the life-threatening effects of opioids, rat study shows

Battle against RSV: Computational design paves way for new polyvalent vaccine

Comparing the cost-effectiveness of SGLT2i versus mineralocorticoid antagonists

Smart drugs fall short as cognitive function enhancers

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