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Higher Paxlovid uptake in winter 2022 could have prevented nearly 5,000 deaths

In a recent study published in the JAMA Health Forum, researchers in the United States estimated the reduction in coronavirus disease 2019 (COVID-19) mortality rates after the Paxlovid rollout.

22 Mar 2023

SARS-CoV-2 infection enhances vaccine-induced immunological memory against spike protein

Researchers assess SARS-CoV-2 spike protein-specific immunological memory among unvaccinated and vaccinated convalescents.

22 Mar 2023

Tetravalent COVID vaccine provides broad antibody responses against SARS-CoV-2 variants in animal model

In a recent study posted to the bioRxiv* preprint server, researchers in Italy and the United States evaluated the efficacy and immunogenicity of an adjuvanted tetravalent severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike (S) protein subunit 1 (S1) COVID-19 vaccine.

21 Mar 2023

Prior COVID and vaccination generate superior hybrid immunity

In a recent article published in the journal Science Translational Medicine, researchers in France performed a long-term longitudinal analysis to demonstrate the benefits of hybrid immunity to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), i.e., induced by viral infection followed by vaccination.

21 Mar 2023

Paxlovid is 80% effective when taken within 5 days of severe COVID

In a recent study published in The Lancet’s Infectious Diseases, researchers in the United States evaluated nirmatrelvir–ritonavir treatment effectiveness against hospitalizations and deaths among coronavirus disease 2019 (COVID-19) outpatients in the United States of America (USA).

21 Mar 2023

Next-gen Mpro inhibitor: Promising new drug candidate against Omicron and other SARS-CoV-2 variants

A recent Nature Signal Transduction and Targeted Therapy journal study demonstrated the potential antiviral activity of a new Mpro inhibitor (SY110) against SARS-CoV-2 Omicron and its sublineages.

21 Mar 2023

The effectiveness of mRNA vaccines during Omicron BA.4/5 predominance

Researchers evaluate vaccine effectiveness for two, three, and four doses of COVID-19 mRNA first-generation vaccines.

21 Mar 2023

Judge signals he could rule to halt sales of common abortion pill

During a four-hour hearing last week that could eliminate nationwide access to a common and widely used abortion pill, federal Judge Matthew Kacsmaryk, of the Northern District of Texas, signaled his conservative Christian beliefs early and often.

20 Mar 2023

XBB/XBB.1.5 subvariant of SARS-CoV-2 shows increased vaccine sensitivity

The study, currently available on the medRxiv* preprint server, indicates that omicron subvariant XBB/XBB.1.5 is more sensitive to vaccine-induced immunity than other co-circulating SARS-CoV-2 variants.

19 Mar 2023

California picks generic drug company Civica to produce low-cost insulin

Gov. Gavin Newsom on Saturday announced the selection of Utah-based generic drug manufacturer Civica to produce low-cost insulin for California, an unprecedented move that makes good on his promise to put state government in direct competition with the brand-name drug companies that dominate the market.

19 Mar 2023

Study confirms the benefit of Paxlovid as an early-stage treatment to prevent COVID-19 hospitalization

A Kaiser Permanente study confirms the benefit of nirmatrelvir-ritonavir, also known as Paxlovid, as an early-stage treatment to prevent hospitalization for people with mild to moderate COVID-19, regardless of prior immunity or age.

17 Mar 2023

Anti-Omicron antibodies are induced by hypermutation with ancestral BNT162b2 COVID vaccine

Scientists from the Republic of Korea have analyzed B-cell receptor repertoires induced by an mRNA-based coronavirus disease 2019 (COVID-19) vaccine and found that somatic hypermutations in B-cell receptor heavy chain are responsible for broadening its specificity for unexposed antigens.

16 Mar 2023

Real-world data on the effectiveness of Sotrovimab as a prophylactic against COVID-19

In a recent study posted in the medRxiv* preprint server, scientists assessed the efficacy of sotrovimab for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) treatment.

16 Mar 2023

Ipsilateral vaccination improves response to second dose of COVID-19 vaccine

Researchers examine whether the involvement of the ipsilateral or contralateral lymph nodes affected the immune response during sequential vaccination.

16 Mar 2023

A novel pan-sarbecovirus vaccine candidate neutralizes Omicron BQ.1.1 and XBB subvariants

Researchers provide evidence that a novel vaccine candidate robustly neutralized SARS-CoV-2 Omicron subvariants BQ.1.1 and XBB.

16 Mar 2023

AI-based drug interaction prediction technology analyzes the interaction between Paxlovid ingredients

KAIST (President Kwang Hyung Lee) announced on the 16th that an advanced AI-based drug interaction prediction technology developed by the Distinguished Professor Sang Yup Lee's research team in the Department of Biochemical Engineering that analyzed the interaction between the PaxlovidTM ingredients that are used as COVID-19 treatment and other prescription drugs was published as a thesis.

16 Mar 2023

Bormioli Pharma announces robust growth in its North American business in 2022

Bormioli Pharma, a global leader partnering with customers to provide comprehensive packaging solutions for injectable drugs, today announced robust growth in its North American business in 2022, with sales increasing more than 40% year-over-year.

16 Mar 2023

Efficacy of a single dose of MVA-BN smallpox vaccine against Mpox

A recent The Lancet Infectious Disease study focussed on estimating the effectiveness of a single dose of MVA-BN against Mpox in England. This observational study was conducted following the large-scale vaccination program that immunized the GBMSM group with the MVA-BN vaccine.

15 Mar 2023

Four COVID-19 booster doses most effective way to prevent critical Omicron BA.5

A study published in JAMA Network Open explores the protective efficacy of previous exposure to omicron subvariants and booster vaccination against severe acute respiratory syndrome coronavirus 2 (SARS‑CoV‑2) omicron BA.5 infection.

15 Mar 2023

Smoking cessation drug may help people stop using cocaine while in treatment for OUD

For some people receiving methadone for treatment of opioid use disorder (OUD), the co-use of opioids and stimulants such as cocaine is an issue.

15 Mar 2023

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Pharmaceutical News

Higher Paxlovid uptake in winter 2022 could have prevented nearly 5,000 deaths

SARS-CoV-2 infection enhances vaccine-induced immunological memory against spike protein

Tetravalent COVID vaccine provides broad antibody responses against SARS-CoV-2 variants in animal model

Prior COVID and vaccination generate superior hybrid immunity

Paxlovid is 80% effective when taken within 5 days of severe COVID

Next-gen Mpro inhibitor: Promising new drug candidate against Omicron and other SARS-CoV-2 variants

The effectiveness of mRNA vaccines during Omicron BA.4/5 predominance

Judge signals he could rule to halt sales of common abortion pill

XBB/XBB.1.5 subvariant of SARS-CoV-2 shows increased vaccine sensitivity

California picks generic drug company Civica to produce low-cost insulin

Study confirms the benefit of Paxlovid as an early-stage treatment to prevent COVID-19 hospitalization

Anti-Omicron antibodies are induced by hypermutation with ancestral BNT162b2 COVID vaccine

Real-world data on the effectiveness of Sotrovimab as a prophylactic against COVID-19

Ipsilateral vaccination improves response to second dose of COVID-19 vaccine

A novel pan-sarbecovirus vaccine candidate neutralizes Omicron BQ.1.1 and XBB subvariants

AI-based drug interaction prediction technology analyzes the interaction between Paxlovid ingredients

Bormioli Pharma announces robust growth in its North American business in 2022

Efficacy of a single dose of MVA-BN smallpox vaccine against Mpox

Four COVID-19 booster doses most effective way to prevent critical Omicron BA.5

Smoking cessation drug may help people stop using cocaine while in treatment for OUD

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

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