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Study sheds light on the mechanisms of brain plasticity induced by fluoxetine

A recent study, published in Neuropsychopharmacology, conducted by researchers from the University of Helsinki and the University of Eastern Finland, sheds light on the mechanisms of neural plasticity induced by the antidepressant fluoxetine.

5 Apr 2023

Shape-shifting antibiotics may be the new weapon against drug-resistant superbugs

In the United States alone, drug-resistant bacteria and fungi infect almost 3 million people per year and kill about 35,000. Antibiotics are essential and effective, but in recent years overuse has led to some bacteria developing resistance to them.

4 Apr 2023

Overcoming challenges in flavivirus vaccine development: Exploring modern vaccine types for Dengue, Zika, and beyond

Researchers discuss the challenges impeding the development of vaccines against flaviviruses.

4 Apr 2023

Oral antiviral CD04872SC shows promise in neutralizing COVID-19 variants, offering hope for broad-spectrum treatment

Researchers discover a small molecule drug candidate that could provide immediate protection against infection with SARS-CoV-2.

4 Apr 2023

Next-level technology for making time-released drugs could be a remedy for missed medications

Missing crucial doses of medicines and vaccines could become a thing of the past thanks to Rice University bioengineers' next-level technology for making time-released drugs.

3 Apr 2023

Crystal engineering strategy could make medicines more soluble and palatable for children

Research conducted at University of Limerick in Ireland has shown that crystal engineering can improve access to a drug used in the treatment of a tropical disease affecting millions worldwide.

3 Apr 2023

Orbit Discovery and Evergreen Discovery collaborate to discover peptides for targeting radiopharmaceuticals

Evergreen Discovery (Evergreen), a leading radiopharmaceutical drug development company with a focus on the treatment and diagnosis of cancer.

From Orbit Discovery 3 Apr 2023

Combating vaccine fatigue: Study offers actionable steps to boost acceptance

Researchers determine whether new vaccination campaigns must be adopted for primary and booster vaccination.

30 Mar 2023

Buprenorphine can be safely started in the ER without triggering withdrawal even for people using stronger opioids

Results from a multi-site clinical trial supported by the National Institutes of Health showed that less than 1% of people with opioid use disorder whose drug use includes fentanyl experienced withdrawal when starting buprenorphine in the emergency department.

30 Mar 2023

States try to obscure execution details as drugmakers hinder lethal injection

In 2011, Jeffrey Motts was executed in South Carolina. More than a decade later, the state hasn't carried out another execution because officials have struggled to obtain the drugs needed for lethal injection.

30 Mar 2023

Next-generation influenza vaccines show greater impact and cost-effectiveness, study suggests

In a recent study published in the BMC Medicine Journal, researchers conducted a modeling study to evaluate the cost-effectiveness and health impacts of the next-generation vaccines against influenza in Kenya.

28 Mar 2023

CBD-based compounds boost the effects of naloxone

There's been a recent push in the U.S. to make naloxone -; a fast-acting opioid antidote -; available without a prescription.

28 Mar 2023

New study suggests broad neutralizing antibody could provide three years of COVID protection

In a recent article published in the journal Science Translational Medicine, researchers showed that a novel, lab-engineered monoclonal antibody (mAb), adintrevimab conferred up to 50% protection against symptomatic coronavirus disease 2019 (COVID-19). Furthermore, it demonstrated this exceptional efficacy in severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)–naïve individuals even at titers as low as 1:30.

27 Mar 2023

Developers of gene therapies can utilize FDA guidance to prepare ODD or RPDD applications

Providing an overview of the submissions process and examples of U.S. Food and Drug Administration (FDA) applications for Orphan Drug Designation (ODD) and Rare Pediatric Disease Designation (RPDD), a new article can help developers of gene therapies for rare genetic diseases.

27 Mar 2023

Metformin may reduce the risk of osteoarthritis

In a recent study published in JAMA Network Open, researchers in the United States (US) determined the risk of osteoarthritis (OA) and joint replacement among adults with type 2 diabetes (T2D) following metformin or sulfonylurea treatment.

27 Mar 2023

Hormonal contraceptives and breast cancer: what's the risk?

The current study, reported in the PLOS Medicine journal, explored breast cancer risk linked to the current or past use of hormonal contraception during the reproductive period in women.

26 Mar 2023

Study finds lack of high certainty evidence on the efficacy and safety of analgesics for low back pain

Despite nearly 60 years of research, there is still a lack of high certainty evidence on the effectiveness and safety of commonly used painkillers (analgesics) for short bouts of low back pain, finds an analysis of the evidence published by The BMJ.

23 Mar 2023

Golden spice commonly found in curry could enhance ovarian cancer treatments

A pharmacology researcher at New York Institute of Technology College of Osteopathic Medicine (NYITCOM) has co-authored a new study that makes a strong case for why a golden spice commonly found in curry could enhance ovarian cancer treatments.

23 Mar 2023

Monovalent vs. bivalent vaccines – Which is more effective against SARS-CoV-2?

In a recent study posted to the medRxiv* preprint server, researchers in France compared the efficacy of Pfizer-BioNTech Original/BA.4-5 bivalent vaccine compared to messenger ribonucleic acid (mRNA) Original (ancestral) monovalent vaccines against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).

22 Mar 2023

Higher Paxlovid uptake in winter 2022 could have prevented nearly 5,000 deaths

In a recent study published in the JAMA Health Forum, researchers in the United States estimated the reduction in coronavirus disease 2019 (COVID-19) mortality rates after the Paxlovid rollout.

22 Mar 2023

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Pharmaceutical News

Study sheds light on the mechanisms of brain plasticity induced by fluoxetine

Shape-shifting antibiotics may be the new weapon against drug-resistant superbugs

Overcoming challenges in flavivirus vaccine development: Exploring modern vaccine types for Dengue, Zika, and beyond

Oral antiviral CD04872SC shows promise in neutralizing COVID-19 variants, offering hope for broad-spectrum treatment

Next-level technology for making time-released drugs could be a remedy for missed medications

Crystal engineering strategy could make medicines more soluble and palatable for children

Orbit Discovery and Evergreen Discovery collaborate to discover peptides for targeting radiopharmaceuticals

Combating vaccine fatigue: Study offers actionable steps to boost acceptance

Buprenorphine can be safely started in the ER without triggering withdrawal even for people using stronger opioids

States try to obscure execution details as drugmakers hinder lethal injection

Next-generation influenza vaccines show greater impact and cost-effectiveness, study suggests

CBD-based compounds boost the effects of naloxone

New study suggests broad neutralizing antibody could provide three years of COVID protection

Developers of gene therapies can utilize FDA guidance to prepare ODD or RPDD applications

Metformin may reduce the risk of osteoarthritis

Hormonal contraceptives and breast cancer: what's the risk?

Study finds lack of high certainty evidence on the efficacy and safety of analgesics for low back pain

Golden spice commonly found in curry could enhance ovarian cancer treatments

Monovalent vs. bivalent vaccines – Which is more effective against SARS-CoV-2?

Higher Paxlovid uptake in winter 2022 could have prevented nearly 5,000 deaths

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

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