Arthritis & Rheumatology News and Research

Latest Arthritis & Rheumatology News and Research

Patients with moderate-to-severe plaque psoriasis achieve significant improvement with ixekizumab

Eli Lilly and Company announced today that patients with moderate-to-severe plaque psoriasis who did not respond to treatment with etanercept achieved significant improvement in their psoriasis plaques when treated with ixekizumab in a Phase 3 clinical trial. Detailed results of the UNCOVER-2 study were presented during the American Academy of Dermatology Annual Meeting taking place March 4-8 in Washington, D.C.

8 Mar 2016

Xencor begins XmAb5871 Phase 2 trials in patients with IgG4-RD and Systemic Lupus Erythematosus

Xencor, Inc., a clinical-stage biopharmaceutical company developing engineered monoclonal antibodies for the treatment of autoimmune diseases, asthma and allergic diseases and cancer, today announced dosing the first patient in a Phase 2 trial of XmAb5871 in patients with IgG4-Related Disease (IgG4-RD).

8 Mar 2016

Systemic sclerosis: an interview with Dr Kristin Highland

Systemic sclerosis, also known as scleroderma, is a rare disease characterized by the thickening and scarring of connective tissue of multiple organs in the body

7 Mar 2016

HSS studies find cartilage restoration procedures as viable treatment for patients over 40 years old

Patients who have cartilage damage in their knees often experience pain and are unable to engage in sports and other activities they enjoy. Two studies at Hospital for Special Surgery find that cartilage restoration procedures are a viable treatment option for patients over 40 years old.

7 Mar 2016

First atomic-scale view of interaction between HIV capsid and host protein cyclophilin A

A new study offers the first atomic-scale view of an interaction between the HIV capsid - the protein coat that shepherds HIV into the nucleus of human cells - and a host protein known as cyclophilin A. This interaction is key to HIV infection, researchers say.

7 Mar 2016

Vitamin D supplements during pregnancy do not improve babies' bone health, but may have seasonal effect

Taking vitamin D supplements during pregnancy, as recommended for all women under UK guidelines, has no significant effect on the bone density of babies, according to the first randomised controlled trial of its kind, published in The Lancet Diabetes & Endocrinology journal.

7 Mar 2016

Modified protein appears to reverse liver fibrosis, cirrhosis in rats

A protein modified to increase the amount of time it circulates in the bloodstream appears to reverse liver fibrosis and cirrhosis in rats, according to results of a study led by Johns Hopkins researchers.

3 Mar 2016

Preoperative hip and knee injections may increase risk for infection

Injections received in the months prior to total knee (TKR) or total hip replacement (THR) surgery may increase the risk for infection and related complications, according to two studies--among the largest conducted on this topic--presented at the 2016 Annual Meeting of the American Academy of Orthopaedic Surgeons.

3 Mar 2016

New AAOS guidelines can help doctors make accurate diagnosis of CTS

New guidelines approved by the American Academy of Orthopaedic Surgeons Board of Directors recommend the collective use of a thorough patient history and specific physical examination maneuvers, in addition to observation and specific diagnostic tests to more definitively diagnose carpal tunnel syndrome, a common source of hand numbness and pain affecting approximately 3 million Americans--primarily women--each year.

3 Mar 2016

First-ever research programme launched to tackle superbugs

To meet the challenge of the rise in antibiotic resistant bacteria, national charity ‘Antibiotic Research UK is commissioning the first ever research programme to screen antibiotic resistance breakers against antibiotic resistance in Gram-negative bacteria.

2 Mar 2016

TSRI researchers find way to predict therapeutic potential of stem cells against different diseases

Scientists from the Florida campus of The Scripps Research Institute have for the first time developed a way to predict how a specific type of stem cell will act against different diseases.

2 Mar 2016

Vitamin D supplementation during pregnancy can help increase bone strength in babies born in winter months

Vitamin D supplementation during pregnancy may lead to stronger bones in babies born during the winter months, a new Southampton study has shown.

2 Mar 2016

Report: One in two Americans affected by musculoskeletal condition

An estimated 126.6 million Americans (one in two adults) are affected by a musculoskeletal condition--comparable to the total percentage of Americans living with a chronic lung or heart condition--costing an estimated $213 billion in annual treatment, care and lost wages, according to a new report issued today by the United States Bone and Joint Initiative.

2 Mar 2016

TTR protein causes autoimmune reaction in joints of juvenile idiopathic arthritis patients

Juvenile idiopathic arthritis, or JIA, is the most common form of childhood arthritis. It appears to be an autoimmune disease, caused by antibodies attacking certain proteins in a person's own tissue. But no "autoantigens" -- the proteins triggering an immune attack -- have been linked to JIA.

27 Feb 2016

New ways to monitor physical activity at workplace

The science of physical activity at work remains understudied despite widespread acceptance that it plays an important role in health. Now, researchers at the Colorado School of Public Health at the University of Colorado Anschutz Medical Campus have published a comprehensive review of ways to monitor physical activity and tools for occupational exposure scientists.

26 Feb 2016

Low-sodium intake has little impact on bone health in postmenopausal women

A low-salt diet does not necessarily translate to stronger bones in postmenopausal women, physician-scientists report.

26 Feb 2016

New review suggests solutions that can help ease chronic pain in women

Women often suffer silently when in pain, whether it's caused by pregnancy discomfort or creaky knees. Yet there are a variety of solutions that can help relieve women of chronic pain, from exercise to identifying triggers, suggests a new review of research related to women and pain by the American Society of Anesthesiologists.

26 Feb 2016

Aggregated forms of transthyretin can trigger JIA development

Juvenile idiopathic arthritis (JIA) is a the most common form of arthritis in children and affects approximately 50,000 individuals in the United States alone. Previous research suggested that autoimmune responses cause JIA, but the specific antigens that are responsible for driving autoimmunity have not been identified.

26 Feb 2016

Immune-suppressing drug can improve cognitive ability of patients with schizophrenia

A recent study of a handful of patients supports mounting evidence that targeted suppression of inflammation packaged with standard therapy can improve the cognitive ability of patients with schizophrenia, physician-scientists report.

25 Feb 2016

Influenza virus can able to circumvent the body's immune system

Influenza is able to mask itself, so that the virus is not initially detected by our immune system. This is the result of new research from Aarhus University. The researchers behind the study hope that the discovery can be used to develop better treatment against influenza and chronic inflammation conditions such as rheumatoid arthritis.

24 Feb 2016

Arthritis & Rheumatology News and Research

Latest Arthritis & Rheumatology News and Research

Patients with moderate-to-severe plaque psoriasis achieve significant improvement with ixekizumab

Xencor begins XmAb5871 Phase 2 trials in patients with IgG4-RD and Systemic Lupus Erythematosus

Systemic sclerosis: an interview with Dr Kristin Highland

HSS studies find cartilage restoration procedures as viable treatment for patients over 40 years old

First atomic-scale view of interaction between HIV capsid and host protein cyclophilin A

Vitamin D supplements during pregnancy do not improve babies' bone health, but may have seasonal effect

Modified protein appears to reverse liver fibrosis, cirrhosis in rats

Preoperative hip and knee injections may increase risk for infection

New AAOS guidelines can help doctors make accurate diagnosis of CTS

First-ever research programme launched to tackle superbugs

TSRI researchers find way to predict therapeutic potential of stem cells against different diseases

Vitamin D supplementation during pregnancy can help increase bone strength in babies born in winter months

Report: One in two Americans affected by musculoskeletal condition

TTR protein causes autoimmune reaction in joints of juvenile idiopathic arthritis patients

New ways to monitor physical activity at workplace

Low-sodium intake has little impact on bone health in postmenopausal women

New review suggests solutions that can help ease chronic pain in women

Aggregated forms of transthyretin can trigger JIA development

Immune-suppressing drug can improve cognitive ability of patients with schizophrenia

Influenza virus can able to circumvent the body's immune system

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

Arthritis & Rheumatology News and Research

Latest Arthritis & Rheumatology News and Research

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

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