Arthritis & Rheumatology News and Research

Latest Arthritis & Rheumatology News and Research

Temple University Hospital is offering COVID-19 clinical trials, investigational treatments options

Temple University Hospital is now participating in a variety of clinical trials that are testing investigational treatment options for patients diagnosed with the novel coronavirus, or COVID-19.

30 Apr 2020

Online searches for unproven therapies for COVID-19

A new observational study by a group of scientists explores the rise in the public's fear-driven interest in unproven therapies for COVID-19, particularly chloroquine and hydroxychloroquine, by tracking the internet searches relating to the purchase of drugs in news reports or publicized by public figures. They conclude: "Stay grounded in evidence and fight misinformation." The research letter and accompanying editorial comment are published in the journal JAMA Internal Medicine.

29 Apr 2020

Testing of hydroxychloroquine for COVID-19 begins at Montefiore And Einstein

Researchers at Montefiore Health System and Albert Einstein College of Medicine have begun testing the drug hydroxychloroquine for the treatment of COVID-19, as part of a nationwide trial sponsored by the National Heart, Lung, and Blood Institute

29 Apr 2020

Arthritis drug assessed as potential treatment for COVID-19-related pneumonia

UC San Diego Health has launched a Phase III clinical trial, part of a global effort, to assess whether a medication used to treat rheumatoid arthritis and other inflammatory disorders might also have therapeutic value for COVID-19 patients who have developed or at high risk of developing serious lung damage from SARS-CoV-2 infections.

29 Apr 2020

CZI announces grants for researchers studying the role of inflammation in disease

Today, the Chan Zuckerberg Initiative announced $14 million in funding to support 29 interdisciplinary teams and build a network of researchers that will explore emerging ideas regarding the role of inflammation in disease.

29 Apr 2020

The challenges of keeping young adults safe during the pandemic

Last month, after California Gov. Gavin Newsom ordered most of the state's residents to stay home, I found myself under virtual house arrest with an uncomfortably large number of Gen Zers.

29 Apr 2020

C-Path receives EMA’s letter of support to facilitate the diagnoses of type 1 diabetes

The Critical Path Institute (C-Path) today announced that its Type 1 Diabetes (T1D) Consortium has received a letter of support from the European Medicines Agency (EMA) to facilitate the development and validation of the proposed regulatory qualification of pancreatic islet autoantibodies commonly used in clinical practice to diagnose T1D: insulin autoantibodies, glutamic acid decarboxylase 65, and insulinoma antigen-2 autoantibodies as enrichment biomarkers for T1D clinical trials.

29 Apr 2020

Gustave Roussy and Biognosys Announce Partnership

The severe pneumonitis in patients infected by SARS-Cov-2 requires prolonged treatment in intensive care units with mechanical ventilation.

From Biognosys 28 Apr 2020

New light-activated drug delivery method helps confine arthritis treatments to the joints

Although today's rheumatoid arthritis treatments can reduce symptoms, they often come with serious side effects. Results from a new mouse study suggest that a new light-activated drug delivery method helps confine treatments to the joints, which could reduce whole-body side effects.

27 Apr 2020

Global healthy living foundation launches autoimmune patient COVID-19 research project

Today the Global Healthy Living Foundation (GHLF) and CreakyJoints®, its digital patient community for people with all forms of arthritis, announced the launch of the Autoimmune COVID-19 Project.

24 Apr 2020

New genome-editing techniques could make recombinant-protein drugs cheaper

The mammalian cell lines that are engineered to produce high-value recombinant-protein drugs also produce unwanted proteins that push up the overall cost to manufacture these drugs. These same proteins can also lower drug quality

24 Apr 2020

Is the confidence in hydroxychloroquine for the management of COVID-19 justified?

A new review paper published in the preprint open-access journal medRxiv in April 2020 reports that there is not enough evidence to justify the widespread use of the drug hydroxychloroquine (HCQ) in the treatment or prophylaxis of the current COVID-19 illness.

23 Apr 2020

A new method to deliver therapeutic proteins inside the body

A new way to deliver therapeutic proteins inside the body uses an acoustically sensitive carrier to encapsulate the proteins and ultrasound to image and guide the package to the exact location required, according to Penn State researchers. Ultrasound then breaks the capsule, allowing the protein to enter the cell.

23 Apr 2020

Meis1 protein plays key role in stopping cell division in the heart

UT Southwestern Medical Center scientists have discovered a protein that works with others during development to put the brakes on cell division in the heart, they report today in Nature.

23 Apr 2020

Using 'own' immune cells to fight infectious diseases including COVID-19

A provocative paper from Duke-NUS Medical School, published in the Journal of Experimental Medicine in March 2020, discusses the possibilities of creating new receptors on a sick person's own immune cells as a means of controlling the infection. This therapy is already being used to treat certain cancers with marked success.

22 Apr 2020

Adults with spinal cord injury are at higher risk of developing mental health disorders

In a new study, published in Mayo Clinic Proceedings, researchers from Michigan Medicine find adults with spinal cord injury are at a higher risk of developing mental health disorders, including depression and anxiety, compared to adults without the condition.

22 Apr 2020

Is hydroxychloroquine effective against COVID-19?

Following the emergence of a novel coronavirus in Wuhan, China, in the last month of 2019, it has spread globally to produce the first pandemic of the 21st century. The virus, called severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has already affected over 2.5 million and killed more than 177,000 people as of April 22, 2020.

22 Apr 2020

Researchers are exploring potential therapy for controlling infectious diseases

The engineering of specific virus-targeting receptors onto a patient's own immune cells is now being explored by scientists from Duke-NUS Medical School (Duke-NUS), as a potential therapy for controlling infectious diseases, including the COVID-19-causing virus, SARS-CoV-2.

22 Apr 2020

Many phase II trials overestimate drug efficacy, pose a barrier in drug licensing

Based on a systematic analysis of trials related to rheumatoid arthritis and psoriasis arthritis, a MedUni Vienna study group at the Division of Rheumatology at MedUni Vienna/Vienna General Hospital was able to show that many clinical phase II trials systematically overestimate the efficacy of therapeutics, so that the results of subsequent phase III trials can often be disappointing. Essentially this situation also applies in many other areas.

21 Apr 2020

Are overactive immune cells causing COVID-19-related deaths?

While the COVID-19 pandemic is devastating many regions, the world over, a new paper published in the Journal of Experimental Medicine in April 2020 describes the possibility that the critical or very severe cases of COVID-19 are due to the production of neutrophil extracellular traps (NET) due to hyperactivated immune cells.

16 Apr 2020

Arthritis & Rheumatology News and Research

Latest Arthritis & Rheumatology News and Research

Temple University Hospital is offering COVID-19 clinical trials, investigational treatments options

Online searches for unproven therapies for COVID-19

Testing of hydroxychloroquine for COVID-19 begins at Montefiore And Einstein

Arthritis drug assessed as potential treatment for COVID-19-related pneumonia

CZI announces grants for researchers studying the role of inflammation in disease

The challenges of keeping young adults safe during the pandemic

C-Path receives EMA’s letter of support to facilitate the diagnoses of type 1 diabetes

Gustave Roussy and Biognosys Announce Partnership

New light-activated drug delivery method helps confine arthritis treatments to the joints

Global healthy living foundation launches autoimmune patient COVID-19 research project

New genome-editing techniques could make recombinant-protein drugs cheaper

Is the confidence in hydroxychloroquine for the management of COVID-19 justified?

A new method to deliver therapeutic proteins inside the body

Meis1 protein plays key role in stopping cell division in the heart

Using 'own' immune cells to fight infectious diseases including COVID-19

Adults with spinal cord injury are at higher risk of developing mental health disorders

Is hydroxychloroquine effective against COVID-19?

Researchers are exploring potential therapy for controlling infectious diseases

Many phase II trials overestimate drug efficacy, pose a barrier in drug licensing

Are overactive immune cells causing COVID-19-related deaths?

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Arthritis & Rheumatology News and Research

Latest Arthritis & Rheumatology News and Research

CellVoyant's AI-Powered Vision for the Future of Cell Therapy

Scalable, Smart, and Accessible: The Future of Lab Automation

Healthy Beginnings, Hopeful Futures: A Conversation with WHO’s Dr. Allotey

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