CRISPR News and Research

Latest CRISPR News and Research

Decoding tauopathies: New study identifies non-coding RNA as a key player in Alzheimer's

Researchers at Washington University School of Medicine identify a key step in the development of harmful tau tangles, offering a potential target for preventing brain damage in diseases like Alzheimer's. The study highlights the role of long noncoding RNAs, particularly SNHG8, in stress granule formation and tau aggregation, opening new avenues for treatment.

22 Sep 2023

Rice engineers develop split gene-editing tool with enhanced control

To make a gene-editing tool more precise and easier to control, Rice University engineers split it into two pieces that only come back together when a third small molecule is added.

21 Sep 2023

Scientists develop Australia’s first-of-its-kind next-gen mpox diagnostic tool

In a collaborative study published in The Lancet Microbe, the team of scientists, led by the Peter Doherty Institute for Infection and Immunity (Doherty Institute) and WEHI (Walter and Eliza Hall Institute of Medical Research), revealed MPXV-CRISPR – a powerful diagnostic tool capable of detecting MPXV in clinical samples with acute precision and at a faster rate than any other method, thanks to the power of CRISPR technology.

20 Sep 2023

Game-changing point-of-care assay could revolutionize Mpox detection worldwide

Researchers developed a point-of-care assay for the rapid detection of mpox virus.

20 Sep 2023

Subclonal neoantigens present a key roadblock in MMRd tumor immunotherapy success

Researchers evaluated sensitivity to immune checkpoint blockade (ICB) therapy.

20 Sep 2023

Research demonstrates a double-acting mechanism for fighting triple-negative breast cancer

Zachary Schug, Ph.D., assistant professor in the Molecular and Cellular Oncogenesis Program of the Ellen and Ronald Caplan Cancer Center at The Wistar Institute, has published a new paper in the journal Nature Cancer.

19 Sep 2023

Researchers identify key mechanisms to address future treatments for hereditary blindness

There are still many enigmas about the mechanism of action of the CERKL gene, which causes retinitis pigmentosa and other hereditary vision diseases.

18 Sep 2023

Researchers identify a rare cause of male infertility and discover a potential cure

Researchers investigated the genetic underpinning of asthenozoospermia, the leading cause of male fertility.

18 Sep 2023

Broken String Biosciences closes $15M series A funding round

Broken String Biosciences today announced that it has closed a $15 million Series A investment round.

From Broken String Biosciences 18 Sep 2023

Single-cell screening of cerebral organoids to identify developmental defects in autism

Researchers develop CRISPR-human organoids-single-cell RNA sequencing system to identify developmental brain defects in autism.

18 Sep 2023

NICER: A safer alternative to CRISPR/Cas9 for gene editing

The gene editing technique CRISPR/Cas9 has allowed researchers to make precise and impactful changes to an organism's DNA to fix mutations that cause genetic disease.

15 Sep 2023

Innovative technique provides unparalleled insight into autism pathology

Does the human brain have an Achilles heel that ultimately leads to Autism? With a revolutionizing novel system that combines brain organoid technology and intricate genetics, researchers can now comprehensively test the effect of multiple mutations in parallel and at a single-cell level within human brain organoids.

13 Sep 2023

Researchers use machine learning to predict drug approval chances before clinical trials

Developing new drugs is paramount in discovering innovative treatments and preventing diseases. This is vital not only for advancing medicine but also for the overall health and well-being of humanity.

8 Sep 2023

RIT researchers use CRISPR to develop new treatment for degenerative disc disease

Rochester Institute of Technology researchers are improving non-invasive treatment options for degenerative disc disease, an ailment that impacts 3 million adults yearly in the U.S., according to the Mayo Clinic.

6 Sep 2023

Pitt neuroscientists create first non-human primate model of hereditary Alzheimer's in marmosets

To reimagine existing preclinical trials for Alzheimer's disease, University of Pittsburgh School of Medicine neuroscientists created the first non-human primate model of hereditary Alzheimer's in marmoset monkeys, outlining their approach in Alzheimer's & Dementia: Translational Research & Clinical Interventions.

6 Sep 2023

Scientists delve deeper into how vaccines work against leishmaniasis

Scientists have established the effectiveness of vaccines they developed to prevent the disfiguring skin disease leishmaniasis in animal studies, and Phase 1 human trial planning is in motion for the most promising candidate.

31 Aug 2023

Study reveals pathogenic mechanism of rare pediatric neurodegenerative disorder

A recent study published in Nature Metabolism has revealed the pathogenic mechanism underlying a rare pediatric neurodegenerative disorder known as mitochondrial enoyl reductase protein-associated neurodegeneration (MEPAN) syndrome.

31 Aug 2023

Universal approach could potentially expand CAR T cell therapy to all blood cancers

A broad new strategy could hold hope for treating virtually all blood cancers with CAR T cell therapy, which is currently approved for five subtypes of blood cancer.

31 Aug 2023

Stem cell gene therapy may offer a promising, curative treatment for sickle cell disease

New research published in the New England Journal of Medicine indicates that stem cell gene therapy may offer a promising, curative treatment for the painful, inherited blood disorder sickle cell disease (SCD).

30 Aug 2023

Scale Biosciences Continues Commercial Expansion with Introduction of New and Differentiated Single Cell Methylation and Single Cell RNA Sequencing Solutions

Scale Biosciences, Inc. (ScaleBioTM), an innovator in single cell sequencing leveraging combinatorial indexing technologies, today announced an expansion of their product portfolio to enable a broader range of single cell omics experiments and unlock new translational research applications.

30 Aug 2023

CRISPR News and Research

Latest CRISPR News and Research

Decoding tauopathies: New study identifies non-coding RNA as a key player in Alzheimer's

Rice engineers develop split gene-editing tool with enhanced control

Scientists develop Australia’s first-of-its-kind next-gen mpox diagnostic tool

Game-changing point-of-care assay could revolutionize Mpox detection worldwide

Subclonal neoantigens present a key roadblock in MMRd tumor immunotherapy success

Research demonstrates a double-acting mechanism for fighting triple-negative breast cancer

Researchers identify key mechanisms to address future treatments for hereditary blindness

Researchers identify a rare cause of male infertility and discover a potential cure

Broken String Biosciences closes $15M series A funding round

Single-cell screening of cerebral organoids to identify developmental defects in autism

NICER: A safer alternative to CRISPR/Cas9 for gene editing

Innovative technique provides unparalleled insight into autism pathology

Researchers use machine learning to predict drug approval chances before clinical trials

RIT researchers use CRISPR to develop new treatment for degenerative disc disease

Pitt neuroscientists create first non-human primate model of hereditary Alzheimer's in marmosets

Scientists delve deeper into how vaccines work against leishmaniasis

Study reveals pathogenic mechanism of rare pediatric neurodegenerative disorder

Universal approach could potentially expand CAR T cell therapy to all blood cancers

Stem cell gene therapy may offer a promising, curative treatment for sickle cell disease

Scale Biosciences Continues Commercial Expansion with Introduction of New and Differentiated Single Cell Methylation and Single Cell RNA Sequencing Solutions

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production