CRISPR News and Research

Latest CRISPR News and Research

Researchers develop new kind of CRISPR screen technology to target RNA

CRISPR-based genetic screens have helped scientists identify genes that are key players in sickle-cell anemia, cancer immunotherapy, lung cancer metastasis, and many other diseases.

16 Mar 2020

Max Planck researchers identify mechanistic basis of antigen receptor gene assembly

Adaptive immunity is a powerful defense mechanism in vertebrates. A finely tuned interplay of different cell types provides a pathogen-specific immune response to eliminate for example bacteria and viruses.

13 Mar 2020

Prize-winning research offers a promising approach to improve regenerative medicine

Joana Neves is the 2019 grand prize winner of the Sartorius & Science Prize for Regenerative Medicine & Cell Therapy, for work that offers a promising approach to improve the outcome of regenerative stem cell-based therapies aimed at delaying age-related degenerative diseases.

12 Mar 2020

Fight for Sight funded researcher develops gene therapy approach for glaucoma

A Fight for Sight funded researcher from the University of Bristol has used gene editing techniques to successfully demonstrate a gene therapy for glaucoma in the lab, in results published in Molecular Therapy in March.

11 Mar 2020

CRISPR-Cas system can be used to effectively target colitis pathogen

Research at North Carolina State University shows that the CRISPR-Cas system can be used to effectively target and eliminate specific gut bacteria, in this case Clostridioides difficile, the pathogen that causes colitis - a chronic, degenerative disease of the colon.

10 Mar 2020

Researchers find way to inactivate cancer protein with the help of another protein

Squamous cell carcinoma is a very unusual type of cancer. They occur in many tissues – for example in the lungs, esophagus, pancreas, throat and pharynx, and on the skin.

10 Mar 2020

Study uncovers novel relationships between SLCs and cytotoxic drugs in human cells

Solute carriers represent the largest family of transmembrane transporters in the human genome, with over 400 members arranged into 65 families.

9 Mar 2020

New genetic tool developed to label specific genes in human organoids

Researchers from the group of Hans Clevers at the Hubrecht Institute have developed a new genetic tool to label specific genes in human organoids, or mini organs.

2 Mar 2020

Researchers explore the role of SLC25A32 in cancer cell proliferation

Oncotarget Volume 11 Issue 8 reported that while it is known that cancer cells require one-carbon and FAD-dependent mitochondrial metabolism to sustain cell proliferation, the role of SLC25A32 in cancer cell growth remains unexplored.

28 Feb 2020

Gene-editing technology may lead to new model for studying Parkinson’s disease

Parkinson's disease researchers have used gene-editing tools to introduce the disorder's most common genetic mutation into marmoset monkey stem cells and to successfully tamp down cellular chemistry that often goes awry in Parkinson's patients.

27 Feb 2020

New form of gene editing slows ALS progression in mice

With a new CRISPR gene-editing methodology, scientists from the University of Illinois at Urbana-Champaign inactivated one of the genes responsible for an inherited form of amyotrophic lateral sclerosis - a debilitating and fatal neurological disease for which there is no cure.

26 Feb 2020

Gene-editing is more error-prone than thought, new findings suggest

The standard gene-editing tool, CRISPR-Cas9, frequently produces a type of DNA mutation that ordinary genetic analysis misses, claims new research published in the journal Proceedings of the National Academy of Sciences.

26 Feb 2020

Large non-protein coding gene regulates process vital to placental implantation in early pregnancy

Abnormal formation and growth of the placenta is considered an underlying cause of various pregnancy complications such as miscarriages, preeclampsia and fetal growth restriction.

25 Feb 2020

Scientists discover new biological mechanism of insulin signaling

In a discovery that may further the understanding of diabetes and human longevity, scientists at Scripps Research have found a new biological mechanism of insulin signaling.

25 Feb 2020

Understanding the arms race between bacteria and viruses

University of Otago researchers have contributed to an international study which helps improve the understanding of bacteria and viruses.

25 Feb 2020

New way to chart human genome with CRISPR/nanopore sequencing technique

In search of new ways to sequence human genomes and read critical alterations in DNA, researchers at Johns Hopkins Medicine say they have successfully used the gene cutting tool CRISPR to make cuts in DNA around lengthy tumor genes, which can be used to collect sequence information.

24 Feb 2020

UT Southwestern scientists discover potential vulnerabilities in new coronavirus

UT Southwestern Medical Center data scientists analyzing genetic sequences of the COVID-19 coronavirus have identified potential vulnerabilities that could help in vaccine development and further study of the infectious disease now spreading worldwide.

17 Feb 2020

Generating genomes and encoding new abilities into artificial DNA

A new study to be presented at the American Association for the Advancement of Science (AAAS) in February 2020 will report on the generation of the world’s first artificially created bacterial genome using a digital design algorithm along with the synthesis of DNA building blocks on a large scale. This genome takes form by chemical rather than template-based synthesis. The research is published in the journal Proceedings of the National Academy of Sciences.

16 Feb 2020

New biological tool can detect and debug faulty genetic circuits

Every cell in our body has a computer-like control system that sends biological signals through thousands of circuits to monitor the cell's needs and regulate its responses.

16 Feb 2020

Scientists pinpoint protein that plays key role in lung cancer and melanoma progression

Scientists from Far Eastern Federal University, University of Geneva (Switzerland), Minjiang University, and Fuzhou University (China) pointed out WDR74 protein playing an important role in lung cancer and melanoma primary tumors/metastases progression.

16 Feb 2020

CRISPR News and Research

Latest CRISPR News and Research

Researchers develop new kind of CRISPR screen technology to target RNA

Max Planck researchers identify mechanistic basis of antigen receptor gene assembly

Prize-winning research offers a promising approach to improve regenerative medicine

Fight for Sight funded researcher develops gene therapy approach for glaucoma

CRISPR-Cas system can be used to effectively target colitis pathogen

Researchers find way to inactivate cancer protein with the help of another protein

Study uncovers novel relationships between SLCs and cytotoxic drugs in human cells

New genetic tool developed to label specific genes in human organoids

Researchers explore the role of SLC25A32 in cancer cell proliferation

Gene-editing technology may lead to new model for studying Parkinson’s disease

New form of gene editing slows ALS progression in mice

Gene-editing is more error-prone than thought, new findings suggest

Large non-protein coding gene regulates process vital to placental implantation in early pregnancy

Scientists discover new biological mechanism of insulin signaling

Understanding the arms race between bacteria and viruses

New way to chart human genome with CRISPR/nanopore sequencing technique

UT Southwestern scientists discover potential vulnerabilities in new coronavirus

Generating genomes and encoding new abilities into artificial DNA

New biological tool can detect and debug faulty genetic circuits

Scientists pinpoint protein that plays key role in lung cancer and melanoma progression

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