CRISPR News and Research

Latest CRISPR News and Research

CRISPR-Gold corrects gene mutations in mice with Duchenne muscular dystrophy

Scientists at the University of California, Berkeley, have engineered a new way to deliver CRISPR-Cas9 gene-editing technology inside cells and have demonstrated in mice that the technology can repair the mutation that causes Duchenne muscular dystrophy, a severe muscle-wasting disease.

4 Oct 2017

“Chemical surgery” on embryos to free them of a gene causing thalassemia

A team of Chinese researchers have for the first time “mended” defective embryos using chemical surgery to free them of a faulty gene that leads to beta thalassemia. Until now this defect was found to be incorrigible caused due to a single misspelling in the DNA code. Beta thalassemia is a dreaded blood disorder wherein the child is unable to make healthy blood needing blood transfusions on a regular basis. The study was published this week in the journal Protein and Cell.

2 Oct 2017

Drug approved to treat parasitic infections also exerts anti-tumor effect on EOC cells

Osaka Researchers, in partnership with other Japanese and U.S. scientists, report a new gene target, KPNB1, for treatment against epithelial ovarian cancer (EOC).

28 Sep 2017

Gene editing technique helps uncover potential new drug targets for KRAS-driven cancers

Cancers driven by mutations in the KRAS gene are among the most deadly. For decades, researchers have tried unsuccessfully to directly target mutant KRAS proteins as a means to treat tumors.

28 Sep 2017

Understanding molecular mechanisms and metabolic pathways of yeast for drug discovery

My research uses budding yeast as a tool for synthetic biology, and also in chemical and functional genomic applications. We are interested in understanding molecular mechanisms and metabolic pathways of yeast for drug discovery.

From Tecan 27 Sep 2017

Scientists use genome editing to understand role of a gene key to human embryonic development

Researchers have used a genome-editing technique to elucidate the role of a gene that is key to human embryonic development.

21 Sep 2017

UI scientists discover gene linked to fatal renal agenesis in children

A team led by University of Iowa researchers has identified a gene linked to rare, often fatal kidney-related birth defects.

18 Sep 2017

Research reveals sugary secrets of protein important for development and cancer progression

The proteins in human cells are extensively decorated with different types of sugars, a phenomenon called glycosylation. These modifications greatly increase the diversity of protein structure and function, affecting how proteins fold, how they behave, and where they go in cells.

15 Sep 2017

Scientists question CRISPR human embryo editing claims

A paper published in the journal Nature on the 2nd August described how a gene editing tool CRISPR could be used to correct a genetic mutation that leads to a heart condition. This team had performed the genetic editing on the gene sequences in dozens of viable human embryos to attempt to prevent a genetic heart condition called hypertrophic cardiomyopathy.

31 Aug 2017

Scientists develop new system to identify and characterize regulatory DNA sequences

Scientists from the Children's Medical Center Research Institute at UT Southwestern have developed an innovative system to identify and characterize the molecular components that control the activities of regulatory DNA sequences in the human genome.

24 Aug 2017

Id genes found to play crucial role in heart development

Researchers from Sanford Burnham Prebys Medical Discovery Institute (SBP), the Cardiovascular Institute at Stanford University and other institutions were surprised to discover that the four genes in the Id family play a crucial role in heart development, telling undifferentiated stem cells to form heart tubes and eventually muscle.

22 Aug 2017

GM pigs one step closer to providing organs for human transplant

US scientists are the closest yet to creating genetically modified pigs with organs that can be safely transplanted into humans.

14 Aug 2017

Counteracting premature aging

Aging is the continuing process of such stress exposures, and with advancing age (normal aging), we must carry lots of senescent cells within our bodies. Senescent cells also often provide some ‘bad influences’ to surrounding healthy cells; such as chronic inflammation and tumorigenesis

14 Aug 2017

New version of gene editing technique corrects molecular mistakes in RNA-based diseases

Until recently, the CRISPR-Cas9 gene editing technique could only be used to manipulate DNA. In a 2016 study, University of California San Diego School of Medicine researchers repurposed the technique to track RNA in live cells in a method called RNA-targeting Cas9 (RCas9).

11 Aug 2017

Xenotransplantation – organ transplants from animals may soon be a reality

Researchers have been able to create genetically modified piglets that are cleaned of the viruses that could causes diseases in humans. This could open up new avenues in organs transplants from pigs to humans. The process of transplanting organs or tissues from animals to humans is called xenotransplantation. The report was published this Tuesday in the journal Science.

11 Aug 2017

Gene-therapy administered through skin transplants could enable treatment of many diseases

A research team based at the University of Chicago has overcome challenges that have limited gene therapy and demonstrated how their novel approach with skin transplantation could enable a wide range of gene-based therapies to treat many human diseases.

3 Aug 2017

IDT introduces first Cas9 enzyme variant that greatly reduces off-target effects in CRISPR genome editing

Integrated DNA Technologies today announced the launch of the first Cas9 enzyme variant that extensively reduces off-target effects in CRISPR genome editing without compromising on-target activity.

3 Aug 2017

Study shows new method for repairing disease-causing mutation in human embryos

Scientists have demonstrated an effective way of using a gene-editing tool to correct a disease-causing gene mutation in human embryos and stop it from passing to future generations.

3 Aug 2017

Research shows great potential of embryonic gene editing to prevent inherited diseases

Scientists have, for the first time, corrected a disease-causing mutation in early stage human embryos with gene editing.

2 Aug 2017

UNM professor receives $1.9-million NIH grant to battle against pervasive African parasite

UNM Distinguished Professor of Biology Eric S. Loker began studying the parasite that causes this disease more than three decades ago and is widely considered one of the world's foremost experts in this field. Loker was recently awarded a five-year, $1.9-million grant from the National Institutes of Health to continue his work in Africa.

2 Aug 2017

CRISPR News and Research

Latest CRISPR News and Research

CRISPR-Gold corrects gene mutations in mice with Duchenne muscular dystrophy

“Chemical surgery” on embryos to free them of a gene causing thalassemia

Drug approved to treat parasitic infections also exerts anti-tumor effect on EOC cells

Gene editing technique helps uncover potential new drug targets for KRAS-driven cancers

Understanding molecular mechanisms and metabolic pathways of yeast for drug discovery

Scientists use genome editing to understand role of a gene key to human embryonic development

UI scientists discover gene linked to fatal renal agenesis in children

Research reveals sugary secrets of protein important for development and cancer progression

Scientists question CRISPR human embryo editing claims

Scientists develop new system to identify and characterize regulatory DNA sequences

Id genes found to play crucial role in heart development

GM pigs one step closer to providing organs for human transplant

Counteracting premature aging

New version of gene editing technique corrects molecular mistakes in RNA-based diseases

Xenotransplantation – organ transplants from animals may soon be a reality

Gene-therapy administered through skin transplants could enable treatment of many diseases

IDT introduces first Cas9 enzyme variant that greatly reduces off-target effects in CRISPR genome editing

Study shows new method for repairing disease-causing mutation in human embryos

Research shows great potential of embryonic gene editing to prevent inherited diseases

UNM professor receives $1.9-million NIH grant to battle against pervasive African parasite

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production