CRISPR News and Research

Latest CRISPR News and Research

Researchers identify strategies to mitigate disturbed axonal transport in ALS patients

A team of researchers at VIB and KU Leuven used stem cell technology to generate motor neurons from ALS patients carrying mutations in FUS. They found disturbed axonal transport in these motor neurons, but also identified genetic and pharmacological strategies that mitigate this defect.

17 Oct 2017

NTNU researchers reveal how HCV converts innocent cells into virus factories

The Hepatitis C (HCV) virus is a sly enemy to have in one's body. Not only does it manage to make itself invisible to the immune system by breaking down communication between the immune cells, it also builds secret virus "factories" that quickly go into mass production.

13 Oct 2017

MIT researchers develop new technique to screen for genes that protect against diseases

Using a modified version of the CRISPR genome-editing system, MIT researchers have developed a new way to screen for genes that protect against specific diseases.

12 Oct 2017

Study documents gene mutation as cause of cancer form in the liver

There is no effective treatment for the cancer form found in the liver called fibrolamellar hepatocellular carcinoma, which is mainly found among children and young people.

12 Oct 2017

Birth control method for men by gene editing

Researchers at the Michigan State University have come closer to finding an effective method of male contraception. Men have been notorious in not choosing to be responsible of their fertility and not adopting contraception.

12 Oct 2017

Genetic discovery provides strong lead for future research on male contraception

When it comes to birth control, many males turn to two options: condoms or vasectomies. While the two choices are effective, both methods merely focus on blocking the transportation of sperm.

10 Oct 2017

TTUHSC El Paso researcher receives $420,000 grant to study mosquito-borne Zika virus

Haoquan Wu, Ph.D., associate professor in the Paul L. Foster School of Medicine, has received a two-year, $420,000 grant from the National Institute of Allergy and Infectious Disease to study the mosquito-borne virus Zika.

10 Oct 2017

New microcapsules represent promising vectors for application of genome-editing tools

Researchers from Tomsk Polytechnic University jointly with their colleagues from St. Petersburg, Hamburg and London have conducted a study in the course of which it was found out that polymer and hybrid silica-coated microcapsules are more efficient in genome-editing when applying CRISPR-Cas9 system.

6 Oct 2017

Researchers pinpoint genetic drivers of diffuse large B cell lymphoma

Lymphoma is the most common blood cancer, but the diagnosis belies a wildly diverse and little understood genetic foundation for the disease that hampers successful treatment.

5 Oct 2017

Study uses ferret model to elucidate key mechanisms for gyrus formation

The human brain is highly developed with higher functions compared to other animals, thanks to which humans are believed to have acquired special abilities. One of the important factors considered to contribute to the development of the brain is the gyrus, the fold on the cerebral cortex surface.

5 Oct 2017

CRISPR-Gold corrects gene mutations in mice with Duchenne muscular dystrophy

Scientists at the University of California, Berkeley, have engineered a new way to deliver CRISPR-Cas9 gene-editing technology inside cells and have demonstrated in mice that the technology can repair the mutation that causes Duchenne muscular dystrophy, a severe muscle-wasting disease.

4 Oct 2017

“Chemical surgery” on embryos to free them of a gene causing thalassemia

A team of Chinese researchers have for the first time “mended” defective embryos using chemical surgery to free them of a faulty gene that leads to beta thalassemia. Until now this defect was found to be incorrigible caused due to a single misspelling in the DNA code. Beta thalassemia is a dreaded blood disorder wherein the child is unable to make healthy blood needing blood transfusions on a regular basis. The study was published this week in the journal Protein and Cell.

2 Oct 2017

Drug approved to treat parasitic infections also exerts anti-tumor effect on EOC cells

Osaka Researchers, in partnership with other Japanese and U.S. scientists, report a new gene target, KPNB1, for treatment against epithelial ovarian cancer (EOC).

28 Sep 2017

Gene editing technique helps uncover potential new drug targets for KRAS-driven cancers

Cancers driven by mutations in the KRAS gene are among the most deadly. For decades, researchers have tried unsuccessfully to directly target mutant KRAS proteins as a means to treat tumors.

28 Sep 2017

Understanding molecular mechanisms and metabolic pathways of yeast for drug discovery

My research uses budding yeast as a tool for synthetic biology, and also in chemical and functional genomic applications. We are interested in understanding molecular mechanisms and metabolic pathways of yeast for drug discovery.

From Tecan 27 Sep 2017

Scientists use genome editing to understand role of a gene key to human embryonic development

Researchers have used a genome-editing technique to elucidate the role of a gene that is key to human embryonic development.

21 Sep 2017

UI scientists discover gene linked to fatal renal agenesis in children

A team led by University of Iowa researchers has identified a gene linked to rare, often fatal kidney-related birth defects.

18 Sep 2017

Research reveals sugary secrets of protein important for development and cancer progression

The proteins in human cells are extensively decorated with different types of sugars, a phenomenon called glycosylation. These modifications greatly increase the diversity of protein structure and function, affecting how proteins fold, how they behave, and where they go in cells.

15 Sep 2017

Scientists question CRISPR human embryo editing claims

A paper published in the journal Nature on the 2nd August described how a gene editing tool CRISPR could be used to correct a genetic mutation that leads to a heart condition. This team had performed the genetic editing on the gene sequences in dozens of viable human embryos to attempt to prevent a genetic heart condition called hypertrophic cardiomyopathy.

31 Aug 2017

Scientists develop new system to identify and characterize regulatory DNA sequences

Scientists from the Children's Medical Center Research Institute at UT Southwestern have developed an innovative system to identify and characterize the molecular components that control the activities of regulatory DNA sequences in the human genome.

24 Aug 2017

CRISPR News and Research

Latest CRISPR News and Research

Researchers identify strategies to mitigate disturbed axonal transport in ALS patients

NTNU researchers reveal how HCV converts innocent cells into virus factories

MIT researchers develop new technique to screen for genes that protect against diseases

Study documents gene mutation as cause of cancer form in the liver

Birth control method for men by gene editing

Genetic discovery provides strong lead for future research on male contraception

TTUHSC El Paso researcher receives $420,000 grant to study mosquito-borne Zika virus

New microcapsules represent promising vectors for application of genome-editing tools

Researchers pinpoint genetic drivers of diffuse large B cell lymphoma

Study uses ferret model to elucidate key mechanisms for gyrus formation

CRISPR-Gold corrects gene mutations in mice with Duchenne muscular dystrophy

“Chemical surgery” on embryos to free them of a gene causing thalassemia

Drug approved to treat parasitic infections also exerts anti-tumor effect on EOC cells

Gene editing technique helps uncover potential new drug targets for KRAS-driven cancers

Understanding molecular mechanisms and metabolic pathways of yeast for drug discovery

Scientists use genome editing to understand role of a gene key to human embryonic development

UI scientists discover gene linked to fatal renal agenesis in children

Research reveals sugary secrets of protein important for development and cancer progression

Scientists question CRISPR human embryo editing claims

Scientists develop new system to identify and characterize regulatory DNA sequences

Scalable, Smart, and Accessible: The Future of Lab Automation

Healthy Beginnings, Hopeful Futures: A Conversation with WHO’s Dr. Allotey

The evolution of OCT for retinal imaging and disease intervention