Circadian Rhythm News and Research

Latest Circadian Rhythm News and Research

Not just humans benefit from animal biotechnology

Laboratory animals are the source of major discoveries and breakthroughs in biology, not just in tackling disease but also unravelling fundamental molecular processes.

25 Oct 2007

The biomedical and sociological effects of sleep restriction

In spring 2005 a large European research and training network was established to investigate the causes and implications of poor sleep from a medical as well as from a social point of view. This EU-financed sleep research project, “The biomedical and sociological effects of sleep restriction”, is coordinated by Dr. Tarja Porkka-Heiskanen (Stenberg) MD, PhD, at the University of Helsinki, Institute of Biomedicine.

22 Oct 2007

Connection between expression of clock genes and sleep

Genes responsible for our 24 hour body clock influence not only the timing of sleep, but also appear to be central to the actual restorative process of sleep, according to research published in the online open access journal BMC Neuroscience.

18 Oct 2007

Study identifies pathway required for normal reproductive development

Massachusetts General Hospital (MGH) clinical researchers, in collaboration with basic scientists from the University of California, Irvine (UC Irvine) have identified a new molecular pathway required for normal development of the reproductive, olfactory and circadian systems in both humans and mice.

17 Oct 2007

Simplest circadian clocks operate via orderly phosphate transfers

Researchers at Harvard University and the Howard Hughes Medical Institute have found that a simple circadian clock found in some bacteria operates by the rhythmic addition and subtraction of phosphate groups at two key locations on a single protein.

4 Oct 2007

Ostructive sleep apnea and continuous positive airway pressure

Researchers in Brazil have found that treating patients who suffer from obstructive sleep apnea (OSA) with continuous positive airway pressure (CPAP) dramatically reduces early indications of atherosclerosis in just months, linking OSA directly to the hardening or narrowing of the arteries.

29 Sep 2007

New mathematical models for circadian rhythm

The internal clock in living beings that regulates sleeping and waking patterns -- usually called the circadian clock -- has often befuddled scientists due to its mysterious time delays.

28 Aug 2007

Thyroid hormones may play important role in sleep regulation

While the thyroid has long been linked to metabolism, cutting-edge research underway at Rutgers University Camden is investigating the possibility that thyroid hormones have an important role in sleep regulation.

9 Aug 2007

Lack of sleep leads to increased urinary output and more salt in urine

Our body's production of urine follows a circadian rhythm. During the day, we experience greater urinary frequency; at night, urine production declines, enabling us to get uninterrupted sleep.

9 Aug 2007

Rotating shift workers have lower levels of serotonin

People who work rotating shifts have significantly lower levels of serotonin, a hormone and neurotransmitter in the central nervous system believed to play an important role in the regulation of sleep, according to a study published in the August 1st issue of the journal SLEEP.

3 Aug 2007

Autonomous glial mechanism may drive circadian rhythms

Glial cells of the nervous system, once thought to function strictly as support cells for neurons, are now thought to actively modulate them.

2 Aug 2007

Sedative drugs help Huntington's disease sufferers

Mice carrying the genetic mutation that causes Huntington's Disease (HD) showed marked improvements in alertness and their ability to learn after they were given drugs that put them to sleep.

18 Jul 2007

Cicardian system suffers and protects from prenatal cocaine exposure

Researchers from Boston University School of Medicine (BUSM) have shown that prenatal cocaine exposure in zebrafish (which share the majority of the same genes with humans) can alter neuronal development and acutely dysregulate the expression of circadian genes and those affecting melatonin signaling, growth and neurotransmission.

11 Jul 2007

Repeated sleep loss affects ability to compensate for lost sleep

We've all experienced that occasional all-too-short night of sleep -- staying out too late at a party on a weeknight, studying into the wee hours for a morning exam or being kept up during the night with a sick child.

4 Jul 2007

Circadian rhythms and genetics

New research from Colorado State University shows that the function of all genes in mammals is based on circadian -- or daily -- rhythms. The study, publishing in PLoS Computational Biology on June 15, refutes the current theory that only 10 percent to 15 percent of all genes were affected by nature's clock.

18 Jun 2007

RAS signaling of circadian output

In the June 15th issue of G&D, Drs. Jay Dunlap and Jennifer Loros, with colleagues at Dartmouth Medical School, have finally cloned the band gene, and have found that it is an allele of ras-1.

17 Jun 2007

Nurses who work the night shift more likely to have poor sleep habits

Nurses who work the night shift are more likely to have poor sleep habits, a practice that can increase the likelihood of committing serious errors that can put the safety of themselves as well as their patients at risk, according to research presented at SLEEP 2007, the 21st Annual Meeting of the Associated Professional Sleep Societies (APSS).

14 Jun 2007

First comprehensive description of sleep and wake patterns of cancer patients using continuous polysomnography

Patients with advanced-stage cancer experience very poor sleep quality and often have troubling staying awake, says Emory University researcher Kathy Parker, PhD, RN.

14 Jun 2007

Examination of cancer-related fatigue

In a special publication sent to thousands of oncologists nationwide this month, University of Rochester Medical Center scientists offer an in-depth examination of cancer-related fatigue, with hope that a better understanding of the topic will prompt new research and treatment.

8 Jun 2007