Circadian Rhythm News and Research

Latest Circadian Rhythm News and Research

Metabolism and aging linked to circadian rhythm

All animals, including humans, have an internal 24-hour clock or circadian rhythm that creates a daily oscillation of body temperature, brain activity, hormone production and metabolism.

20 Mar 2009

Compound is key coordinator of clock and metabolism

Our circadian clock, or biological timing system, governs our daily cycles of feeding, activity and sleep.

20 Mar 2009

Body clock regulates energy levels in cells

UC Irvine researchers have discovered that circadian rhythms - our own body clock - regulate energy levels in cells.

12 Mar 2009

Valdoxan granted marketing authorisation for the treatment of major depressive episodes in Europe

The European Commission has granted marketing authorisation for Servier's Valdoxan/Thymanax (agomelatine), the first melatonergic antidepressant for the treatment of adult patients with major depressive episodes.

24 Feb 2009

Disruption of circadian clock can suppress cancer growth

Researchers at the University of North Carolina at Chapel Hill have shown that disruption of the circadian clock - the internal time-keeping mechanism that keeps the body running on a 24-hour cycle - can slow the progression of cancer.

3 Feb 2009

Shift workers' body clocks studied to prevent certain cancers

Does shift work predispose you to cancer by altering the body's response to hormones?

2 Feb 2009

Time of day influences response to chemotherapy

For years, research has hinted that the time of day that cancer patients receive chemotherapy can impact their chances of survival.

14 Jan 2009

High-fat diet can disrupt our biological clock

Indulgence in a high-fat diet can not only lead to overweight because of excessive calorie intake, but also can affect the balance of circadian rhythms - everyone's 24-hour biological clock, Hebrew University of Jerusalem researchers have shown.

29 Dec 2008

Research suggests that immunity is stronger at night

The immune system's battle against invading bacteria reaches its peak activity at night and is lowest during the day.

14 Dec 2008

Postpartum depression can lead to poor sleep quality

A study published in the current issue of the Journal of Obstetric, Gynecologic, & Neonatal Nursing shows that depression symptoms worsen in PPD patients when their quality of sleep declines.

10 Dec 2008

Scientists find 12 new genes with potential as drug targets

Scientists have identified 12 new genes that are somewhat strange bedfellows: Some link gallstones and blood cholesterol levels, others link melatonin and sleep patterns to small increases in glucose levels and larger jumps in the risk of diabetes.

8 Dec 2008

Body clock and sleep patterns linked to diabetes and high blood sugar

Diabetes and high levels of blood sugar may be linked to abnormalities in a person's body clock and sleep patterns, according to a genome-wide association study published today in the journal Nature Genetics.

7 Dec 2008

Light exposure therapy, dark sunglasses help night-shift workers

A new study finds the use of light exposure therapy, dark sunglasses and a strict sleep schedule can help night-shift workers create a "compromise circadian phase position," which may result in increased performance and alertness during night shifts while still allowing adequate nighttime sleep on days off.

3 Dec 2008

New evidence shows that the heart beats to its own drummer

They've uncovered some of the molecular circuitry within the cardiovascular system itself that controls the daily rise and fall of blood pressure and heart rate. The findings might also explain why commonly used diabetes drugs come with cardiovascular benefits, according to the researchers.

3 Dec 2008

New sleeping pill could be the answer to jet lag

An experimental drug developed by Australian scientists could offer a new cure for jet lag and be a welcome alternative to addictive sedatives such as benzodiazepines.

3 Dec 2008

New drug tasimelteon may cure jet lag

A team of researchers from Monash University, The Brigham and Women's Hospital (Boston), Harvard Medical School and Vanda Pharmaceuticals has found a new drug with the potential to alleviate jet lag and sleep disorders caused by shift work.

3 Dec 2008

Valdoxan - a melatonergic antidepressant - receives positive European opinion for major depressive disorder

The first melatonergic antidepressant - Valdoxan/Thymanax (agomelatine) - has received a positive opinion from the European Medicines Agency's (EMEA) Committee for Medicinal Products for Human Use (CHMP) for its use in the treatment of adult patients with major depressive disorder (MDD).

21 Nov 2008

Daily rhythms in endothelial cells may explain why heart attacks occur most often in early morning hours

It's not just the stress of going to work. Daily rhythms in the activity of cells that line blood vessels may help explain why heart attacks and strokes occur most often in early morning hours, researchers from Emory University School of Medicine have found.

11 Nov 2008