Cirrhosis News and Research

Latest Cirrhosis News and Research

FDA approves fixed-dose combination tablet for treating adults with chronic hepatitis C

The U.S. Food and Drug Administration today approved Vosevi to treat adults with chronic hepatitis C virus (HCV) genotypes 1-6 without cirrhosis (liver disease) or with mild cirrhosis.

18 Jul 2017

Computational analysis of open-access data points to new ways of using drugs

A research team led by scientists at UC San Francisco has developed a computational method to systematically probe massive amounts of open-access data to discover new ways to use drugs, including some that have already been approved for other uses.

12 Jul 2017

New study links hepatic inflammation to western diet

A new study in The American Journal of Pathology reports that mice fed a Western diet, which is high in fat and sugar, resulted in hepatic inflammation, especially in males. Moreover, liver inflammation was most pronounced in Western diet-fed male mice that also lacked farnesoid x receptor (FXR), a bile acid receptor.

12 Jul 2017

New LI-RADS can improve interpretation of CT and MR imaging

Radiologists can improve their consistency of interpreting and reporting CT and MR imaging of liver cancer with a new version of the Liver Imaging Reporting and Data System.

6 Jul 2017

Singapore researchers discover new mechanism in the liver's response to blocked bile ducts

A multi-disciplinary team of researchers from the Mechanobiology Institute, Singapore at the National University of Singapore, the Institute of Bioengineering and Nanotechnology of A*STAR, and BioSyM, Singapore-MIT Alliance for Research and Technology have described the mechanical principles adopted by liver cells as they remove excess bile during obstructive cholestasis.

30 Jun 2017

New study uncovers low rates of palliative care referral in patients with end-stage liver disease

A new study has uncovered low rates of referral for palliative care in US patients with end-stage liver disease, although rates have been slowly increasing over time.

29 Jun 2017

Drinking few cups of coffee or tea may protect against liver fibrosis, study finds

Chronic liver diseases rank as the 12th cause of death worldwide and many of these disorders are associated with unhealthy lifestyles. Conversely, a healthier lifestyle can help prevent or reverse liver disease.

6 Jun 2017

Patients who undergo Fontan surgery for congenital heart defect have liver fibrosis risk, study reveals

Patients who undergo the Fontan operation as children for a complex congenital heart defect are at risk of developing progressive liver fibrosis, a buildup of fibrous deposits, as a result of the circulation created by the surgery, according to a new study.

31 May 2017

New drug offers hope to patients with hepatitis C

Patients with hepatitis C who suffer from advanced stages of liver disease have renewed hope, thanks to findings by researchers who have discovered that a new drug significantly reduces their risk of death and need for transplantation.

26 May 2017

Researchers link intestinal fungi to increased risk of death in patients with alcoholic liver disease

Liver cirrhosis is the 12th leading cause of mortality worldwide and approximately half of those deaths are due to alcohol abuse.

23 May 2017

MAGNET study: MRE can be accurate, non-invasive tool to detect liver fibrosis in children

Researchers at University of California San Diego School of Medicine, with collaborators across the nation, have determined that magnetic resonance elastography can be an accurate, non-invasive tool to identify liver fibrosis in children.

12 May 2017

Statins may provide favorable effects in patients with HBV- or HCV-related cirrhosis

Infection with hepatitis B virus (HBV) or hepatitis C virus (HCV) can lead to cirrhosis as well as liver cancer. A Hepatology study from Taiwan has found that statins may provide benefits to patients with HBV- or HCV-related cirrhosis.

8 May 2017

Study uncovers potential new therapeutic targets for HCV infections

An international study led by researchers at Monash University' Biomedicine Discovery Institute (BDI) has shone light on the way the Hepatitis C Virus (HCV) hijacks the communication systems in the host cells it infects, uncovering potential new therapeutic targets for the disease.

8 May 2017

Specific genotype may predict recovery in patients with advanced cirrhosis after hepatitis c treatment

Genotyping of patients with advanced cirrhosis from hepatitis C virus could help health-care professionals predict the likelihood of improvement after successful hepatitis C treatment, thus minimizing the need for liver transplants.

8 May 2017

Study shows how probiotic improves integrity of the GI epithelial cell wall in HIV patients

A newly released study published in the Journal of Immunity, Inflammation and Disease and conducted by the Sapienza University of Rome, Italy, found a multi-strain, high concentration, probiotic formulation that helped reconstitute the physical and immunological integrity of the gastrointestinal lining in HIV-1-positive patients on antiretroviral therapy.

3 May 2017

Researchers uncover new mechanism that explains cause of portal hypertension

Investigators at the Medical University of South Carolina have identified a critical regulatory mechanism for the production of nitric oxide. Endothelial nitric oxide synthase is the enzyme responsible for the production of NO and its activity is tightly controlled in liver endothelial cells via a series of complex molecular mechanisms; however, in liver injury, eNOS activity, and subsequently NO production, is dysregulated.

3 May 2017

Infantile spasms and multiple sclerosis relapse data presented at AAN

Mallinckrodt plc, a specialty pharmaceutical company, announced new results from two company-sponsored studies: one study on use of H.P. Acthar® Gel (repository corticotropin injection) in patients with infantile spasms (IS) and a second study on the economic burden of moderate-to-severe multiple sclerosis (MS) relapse.

2 May 2017

Study sets stage for potential stool-based test to detect advanced liver fibrosis

Nonalcoholic fatty liver disease (NAFLD) - a condition that can lead to liver cirrhosis and cancer -; isn't typically detected until it's well advanced. Even then, diagnosis requires an invasive liver biopsy.

2 May 2017

Researchers take important step toward using transplanted fetal cells to treat liver failure

In a new study, researchers demonstrate successful transplantation of fetal rat liver cells to an injured adult rat liver. The work is an important step toward using transplanted cells to treat liver failure, which currently requires an organ transplant.

26 Apr 2017

Obesity amplifies effects of three risk alleles linked to NAFLD

An international study based at UT Southwestern Medical Center revealed a striking genetic-environmental interaction: Obesity significantly amplifies the effects of three gene variants that increase risk of nonalcoholic fatty liver disease by different metabolic pathways.

26 Apr 2017

Cirrhosis News and Research

Latest Cirrhosis News and Research

FDA approves fixed-dose combination tablet for treating adults with chronic hepatitis C

Computational analysis of open-access data points to new ways of using drugs

New study links hepatic inflammation to western diet

New LI-RADS can improve interpretation of CT and MR imaging

Singapore researchers discover new mechanism in the liver's response to blocked bile ducts

New study uncovers low rates of palliative care referral in patients with end-stage liver disease

Drinking few cups of coffee or tea may protect against liver fibrosis, study finds

Patients who undergo Fontan surgery for congenital heart defect have liver fibrosis risk, study reveals

New drug offers hope to patients with hepatitis C

Researchers link intestinal fungi to increased risk of death in patients with alcoholic liver disease

MAGNET study: MRE can be accurate, non-invasive tool to detect liver fibrosis in children

Statins may provide favorable effects in patients with HBV- or HCV-related cirrhosis

Study uncovers potential new therapeutic targets for HCV infections

Specific genotype may predict recovery in patients with advanced cirrhosis after hepatitis c treatment

Study shows how probiotic improves integrity of the GI epithelial cell wall in HIV patients

Researchers uncover new mechanism that explains cause of portal hypertension

Infantile spasms and multiple sclerosis relapse data presented at AAN

Study sets stage for potential stool-based test to detect advanced liver fibrosis

Researchers take important step toward using transplanted fetal cells to treat liver failure

Obesity amplifies effects of three risk alleles linked to NAFLD

Precision in every drop: Inside Hamilton’s syringe technology

Exploring the Future of Neuroscience Drug Discovery

Genomic conservation in Thailand's mangroves

Cirrhosis News and Research

Latest Cirrhosis News and Research

Precision in every drop: Inside Hamilton’s syringe technology

Exploring the Future of Neuroscience Drug Discovery

Genomic conservation in Thailand's mangroves

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