Cirrhosis News and Research

Latest Cirrhosis News and Research

FDA approves new combo drug Mavyret for adults with Hepatitis C infection

Yesterday the U.S. Food and Drug Administration gave its approval to Mavyret (glecaprevir and pibrentasvir) for the treatment of adults with chronic hepatitis C infection. These patients are infected with the Hepatitis C virus (HCV) of genotypes 1-6 and are those that have not developed liver cirrhosis or those who have developed mild cirrhosis. The approval for Mavyret was given to AbbVie Inc.

3 Aug 2017

U.S. FDA approves updated labeling for pan-genotypic single tablet regimen for HCV/HIV co-infected patients

Gilead Sciences, Inc. today announced that the U.S. Food and Drug Administration has approved updated labeling for Epclusa (sofosbuvir 400mg/velpatasvir 100mg), the first all-oral, pan-genotypic, once-daily single tablet regimen (STR) for the treatment of adults with chronic hepatitis C virus (HCV) infection, to include use in patients co-infected with HIV.

1 Aug 2017

ECDC highlights need to scale-up efforts for eliminating viral hepatitis in Europe

An estimated 4.7 million Europeans are living with chronic hepatitis B and almost 4 million (3.9) with chronic hepatitis C infection.

26 Jul 2017

Men with hepatitis B more likely to develop severe liver disease despite lifestyle choices

Why men with hepatitis B remain more than twice as likely to develop severe liver disease than women remains a mystery, even after a study led by a recent Drexel University graduate took lifestyle choices and environments into account.

25 Jul 2017

Princeton scientists test cell-culture system to aid study of HBV infections

Scientists from Princeton University's Department of Molecular Biology have successfully tested a cell-culture system that will allow researchers to perform laboratory-based studies of long-term hepatitis B virus (HBV) infections

25 Jul 2017

Joint research initiative aims to employ novel lifestyle intervention to treat NAFLD

Non-alcoholic fatty liver disease (NAFLD) is one of the most frequent liver diseases worldwide and an estimated 20 million people in Germany are affected.

25 Jul 2017

FDA approves fixed-dose combination tablet for treating adults with chronic hepatitis C

The U.S. Food and Drug Administration today approved Vosevi to treat adults with chronic hepatitis C virus (HCV) genotypes 1-6 without cirrhosis (liver disease) or with mild cirrhosis.

18 Jul 2017

Computational analysis of open-access data points to new ways of using drugs

A research team led by scientists at UC San Francisco has developed a computational method to systematically probe massive amounts of open-access data to discover new ways to use drugs, including some that have already been approved for other uses.

12 Jul 2017

New study links hepatic inflammation to western diet

A new study in The American Journal of Pathology reports that mice fed a Western diet, which is high in fat and sugar, resulted in hepatic inflammation, especially in males. Moreover, liver inflammation was most pronounced in Western diet-fed male mice that also lacked farnesoid x receptor (FXR), a bile acid receptor.

12 Jul 2017

New LI-RADS can improve interpretation of CT and MR imaging

Radiologists can improve their consistency of interpreting and reporting CT and MR imaging of liver cancer with a new version of the Liver Imaging Reporting and Data System.

6 Jul 2017

Singapore researchers discover new mechanism in the liver's response to blocked bile ducts

A multi-disciplinary team of researchers from the Mechanobiology Institute, Singapore at the National University of Singapore, the Institute of Bioengineering and Nanotechnology of A*STAR, and BioSyM, Singapore-MIT Alliance for Research and Technology have described the mechanical principles adopted by liver cells as they remove excess bile during obstructive cholestasis.

30 Jun 2017

New study uncovers low rates of palliative care referral in patients with end-stage liver disease

A new study has uncovered low rates of referral for palliative care in US patients with end-stage liver disease, although rates have been slowly increasing over time.

29 Jun 2017

Drinking few cups of coffee or tea may protect against liver fibrosis, study finds

Chronic liver diseases rank as the 12th cause of death worldwide and many of these disorders are associated with unhealthy lifestyles. Conversely, a healthier lifestyle can help prevent or reverse liver disease.

6 Jun 2017

Patients who undergo Fontan surgery for congenital heart defect have liver fibrosis risk, study reveals

Patients who undergo the Fontan operation as children for a complex congenital heart defect are at risk of developing progressive liver fibrosis, a buildup of fibrous deposits, as a result of the circulation created by the surgery, according to a new study.

31 May 2017

New drug offers hope to patients with hepatitis C

Patients with hepatitis C who suffer from advanced stages of liver disease have renewed hope, thanks to findings by researchers who have discovered that a new drug significantly reduces their risk of death and need for transplantation.

26 May 2017

Researchers link intestinal fungi to increased risk of death in patients with alcoholic liver disease

Liver cirrhosis is the 12th leading cause of mortality worldwide and approximately half of those deaths are due to alcohol abuse.

23 May 2017

MAGNET study: MRE can be accurate, non-invasive tool to detect liver fibrosis in children

Researchers at University of California San Diego School of Medicine, with collaborators across the nation, have determined that magnetic resonance elastography can be an accurate, non-invasive tool to identify liver fibrosis in children.

12 May 2017

Statins may provide favorable effects in patients with HBV- or HCV-related cirrhosis

Infection with hepatitis B virus (HBV) or hepatitis C virus (HCV) can lead to cirrhosis as well as liver cancer. A Hepatology study from Taiwan has found that statins may provide benefits to patients with HBV- or HCV-related cirrhosis.

8 May 2017

Study uncovers potential new therapeutic targets for HCV infections

An international study led by researchers at Monash University' Biomedicine Discovery Institute (BDI) has shone light on the way the Hepatitis C Virus (HCV) hijacks the communication systems in the host cells it infects, uncovering potential new therapeutic targets for the disease.

8 May 2017

Specific genotype may predict recovery in patients with advanced cirrhosis after hepatitis c treatment

Genotyping of patients with advanced cirrhosis from hepatitis C virus could help health-care professionals predict the likelihood of improvement after successful hepatitis C treatment, thus minimizing the need for liver transplants.

8 May 2017

Cirrhosis News and Research

Latest Cirrhosis News and Research

FDA approves new combo drug Mavyret for adults with Hepatitis C infection

U.S. FDA approves updated labeling for pan-genotypic single tablet regimen for HCV/HIV co-infected patients

ECDC highlights need to scale-up efforts for eliminating viral hepatitis in Europe

Men with hepatitis B more likely to develop severe liver disease despite lifestyle choices

Princeton scientists test cell-culture system to aid study of HBV infections

Joint research initiative aims to employ novel lifestyle intervention to treat NAFLD

FDA approves fixed-dose combination tablet for treating adults with chronic hepatitis C

Computational analysis of open-access data points to new ways of using drugs

New study links hepatic inflammation to western diet

New LI-RADS can improve interpretation of CT and MR imaging

Singapore researchers discover new mechanism in the liver's response to blocked bile ducts

New study uncovers low rates of palliative care referral in patients with end-stage liver disease

Drinking few cups of coffee or tea may protect against liver fibrosis, study finds

Patients who undergo Fontan surgery for congenital heart defect have liver fibrosis risk, study reveals

New drug offers hope to patients with hepatitis C

Researchers link intestinal fungi to increased risk of death in patients with alcoholic liver disease

MAGNET study: MRE can be accurate, non-invasive tool to detect liver fibrosis in children

Statins may provide favorable effects in patients with HBV- or HCV-related cirrhosis

Study uncovers potential new therapeutic targets for HCV infections

Specific genotype may predict recovery in patients with advanced cirrhosis after hepatitis c treatment

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Cirrhosis News and Research

Latest Cirrhosis News and Research

CellVoyant's AI-Powered Vision for the Future of Cell Therapy

Scalable, Smart, and Accessible: The Future of Lab Automation

Healthy Beginnings, Hopeful Futures: A Conversation with WHO’s Dr. Allotey

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