Cirrhosis News and Research

Latest Cirrhosis News and Research

Researchers gain new insights into hepatitis B virus

Researchers at the University of Delaware, working with colleagues at Indiana University, have gained new insights into the virus that causes hepatitis B -- a life-threatening and incurable infection that afflicts more than 250 million people worldwide.

4 Jun 2018

MiNA Therapeutics announces initial results from phase I trial of saRNA candidate in liver cancer patients

MiNA Therapeutics, the pioneer in RNA activation therapeutics, today announced preliminary results from its ongoing Phase I study of small activating RNA candidate MTL-CEBPA in advanced liver cancer.

4 Jun 2018

Researchers study effects of specific gut enterobacterium on body fat mass

A research project performed at the universities of Jyväskylä and Turku studied the effects of a specific gut enterobacterium on body fat mass.

1 Jun 2018

New mathematical model holds potential to improve treatment for Hepatitis C infection

The University of Surrey has created a new mathematical model that details how the Hepatitis C infection develops and behaves more accurately than previous models. This new model has the potential to improve treatment for the infection that affects 215,000 people in the United Kingdom.

30 May 2018

Scientists develop lab-based system to study mechanisms of common liver disease

Scientists have developed a lab-based system for studying the most common type of liver disease, paving the way for research into new therapies.

23 May 2018

Scientists find how immune system helps to clear HBV infection after treatment interruption

Scientists from Karolinska Institutet and Hannover Medical School have published two studies that provide insights into how the immune system responds and helps to clear a hepatitis B infection after treatment interruption.

17 May 2018

Key metabolites shed by gut bacteria can help protect from inflammation, study finds

Researchers at Tufts University have elucidated a mechanism by which the "good" bacteria that reside in our gastrointestinal tract can help protect us from inflammation, and how their disruption (dysbiosis) can increase the susceptibility of the liver to more harmful forms of disease.

4 May 2018

Research shows prevalence, health-care utilization, and costs of alcohol-related cirrhosis

More than one-third of cirrhosis cases are related to alcohol, a seven-year national study of more than 100 million privately insured people has found.

4 May 2018

Study: HCV-exposed infants not adequately screened, despite increased prevalence

Due to the opioid epidemic, hepatitis C virus is increasing among pregnant women, resulting in a greater risk of perinatal transmission and HCV infection among children.

2 May 2018

New studies related to causes of liver degradation and possible treatments

A treatment gap remains for many conditions involving damage to the liver, the body's main organ for removing toxins, among other functions. The Experimental Biology 2018 meeting (EB 2018) will feature important research announcements related to the causes of liver degradation and possible treatments.

23 Apr 2018

Single FMT enema produces sustained and significant improvements in cognitive function

A single treatment using an optimized, targeted form of faecal microbiota transplantation (FMT) produces sustained clinical and cognitive improvements, according to the results of a long-term follow-up of patients with liver cirrhosis and hepatic encephalopathy (HE) who had participated in a short-term study.

16 Apr 2018

OCA treatment stabilizes or reverses fibrosis/cirrhosis in patients with primary biliary cholangitis

The first results from the POISE biopsy sub-study have today confirmed that long-term treatment with obeticholic acid leads to the reversal or stabilization of fibrosis/cirrhosis in patients with primary biliary cholangitis who have had an incomplete response to ursodeoxycholic acid.

13 Apr 2018

Study confirms no survival benefit of adding SIRT to standard treatment for liver cancer

The final results of the palliative cohort of the SORAMIC study in patients with unresectable, locally advanced primary liver cancer have confirmed no clinical advantage to adding selective internal radiation therapy to standard sorafenib treatment compared with using sorafenib alone.

13 Apr 2018

Study: One-third of bacterial infections in patients with cirrhosis induced by MDR bacteria

A worldwide study initiated to investigate the epidemiology and outcomes of bacterial infections in hospitalized patients with liver cirrhosis has reported a prevalence of multi-drug-resistant bacteria of 34% and significant regional differences in the risk of developing a multi-drug-resistant infection.

13 Apr 2018

New, sensitive HBV assay may allow earlier detection of hepatocellular carcinoma

Chronic hepatitis B virus (HBV) can progress to cirrhosis and hepatocellular carcinoma (HCC). A study published in The Journal of Molecular Diagnostics describes a new HBV assay that offers advantages over currently used methods because it has the capability to detect closed circular DNA (cccDNA) in serum, single cells, and preserved tissue samples.

12 Apr 2018

Mediterranean-style diet linked to greater gut microbial diversity, lower risk of hospitalization

A diet that is Mediterranean style, and rich in vegetables and fermented milk products such as yoghurt, along with coffee, tea and chocolate, is associated with greater gut microbial diversity and a lower risk of hospitalization in patients with liver cirrhosis, according to the results of an international study presented today at The International Liver Congress™ 2018 in Paris, France.

12 Apr 2018

ALIVER produces animated short-film to raise public awareness about liver disease

An animated short-film produced by the ALIVER consortium titled "Life After Liver Failure", premieres tomorrow morning at the BioTech Village in The International Liver Congress 2018.

11 Apr 2018

Study offers new hope for patients with intrahepatic cholangiocarcinoma

Kandice Fogle, 43, had just moved to Houston when she began experiencing pain in her back and groin. After undergoing a CT scan, doctors found a large mass in her liver. A biopsy confirmed that she had intrahepatic cholangiocarcinoma, more commonly known as bile duct cancer.

11 Apr 2018

Scientists develop and validate rapid point-of-care HCV assay

One of the major challenges identified by the WHO in efforts to eradicate the hepatitis C virus (HCV) is the diagnosis of chronic cases that are generally asymptomatic.

10 Apr 2018

Experts explore how degenerative processes impair the body's detoxification system

A poor diet and other risk factors can result in liver disease. This important metabolic organ can become fatty and inflamed. In the long term, this may result in irreversible and life-threatening organ damage (cirrhosis of the liver or 'shrunken liver').

9 Apr 2018

Cirrhosis News and Research

Latest Cirrhosis News and Research

Researchers gain new insights into hepatitis B virus

MiNA Therapeutics announces initial results from phase I trial of saRNA candidate in liver cancer patients

Researchers study effects of specific gut enterobacterium on body fat mass

New mathematical model holds potential to improve treatment for Hepatitis C infection

Scientists develop lab-based system to study mechanisms of common liver disease

Scientists find how immune system helps to clear HBV infection after treatment interruption

Key metabolites shed by gut bacteria can help protect from inflammation, study finds

Research shows prevalence, health-care utilization, and costs of alcohol-related cirrhosis

Study: HCV-exposed infants not adequately screened, despite increased prevalence

New studies related to causes of liver degradation and possible treatments

Single FMT enema produces sustained and significant improvements in cognitive function

OCA treatment stabilizes or reverses fibrosis/cirrhosis in patients with primary biliary cholangitis

Study confirms no survival benefit of adding SIRT to standard treatment for liver cancer

Study: One-third of bacterial infections in patients with cirrhosis induced by MDR bacteria

New, sensitive HBV assay may allow earlier detection of hepatocellular carcinoma

Mediterranean-style diet linked to greater gut microbial diversity, lower risk of hospitalization

ALIVER produces animated short-film to raise public awareness about liver disease

Study offers new hope for patients with intrahepatic cholangiocarcinoma

Scientists develop and validate rapid point-of-care HCV assay

Experts explore how degenerative processes impair the body's detoxification system

Industry Focus eBook - Pharmaceutical manufacturing (2nd edition) eBook

Advancing brain microphysiological systems (bMPS)

PhD researcher at LifeArc

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

Cirrhosis News and Research

Latest Cirrhosis News and Research

Industry Focus eBook - Pharmaceutical manufacturing (2nd edition) eBook

Advancing brain microphysiological systems (bMPS)

PhD researcher at LifeArc

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

Newsletters you may be interested in