Cirrhosis News and Research

Latest Cirrhosis News and Research

Study shows how probiotic improves integrity of the GI epithelial cell wall in HIV patients

A newly released study published in the Journal of Immunity, Inflammation and Disease and conducted by the Sapienza University of Rome, Italy, found a multi-strain, high concentration, probiotic formulation that helped reconstitute the physical and immunological integrity of the gastrointestinal lining in HIV-1-positive patients on antiretroviral therapy.

3 May 2017

Researchers uncover new mechanism that explains cause of portal hypertension

Investigators at the Medical University of South Carolina have identified a critical regulatory mechanism for the production of nitric oxide. Endothelial nitric oxide synthase is the enzyme responsible for the production of NO and its activity is tightly controlled in liver endothelial cells via a series of complex molecular mechanisms; however, in liver injury, eNOS activity, and subsequently NO production, is dysregulated.

3 May 2017

Infantile spasms and multiple sclerosis relapse data presented at AAN

Mallinckrodt plc, a specialty pharmaceutical company, announced new results from two company-sponsored studies: one study on use of H.P. Acthar® Gel (repository corticotropin injection) in patients with infantile spasms (IS) and a second study on the economic burden of moderate-to-severe multiple sclerosis (MS) relapse.

2 May 2017

Study sets stage for potential stool-based test to detect advanced liver fibrosis

Nonalcoholic fatty liver disease (NAFLD) - a condition that can lead to liver cirrhosis and cancer - isn't typically detected until it's well advanced. Even then, diagnosis requires an invasive liver biopsy.

2 May 2017

Researchers take important step toward using transplanted fetal cells to treat liver failure

In a new study, researchers demonstrate successful transplantation of fetal rat liver cells to an injured adult rat liver. The work is an important step toward using transplanted cells to treat liver failure, which currently requires an organ transplant.

26 Apr 2017

Obesity amplifies effects of three risk alleles linked to NAFLD

An international study based at UT Southwestern Medical Center revealed a striking genetic-environmental interaction: Obesity significantly amplifies the effects of three gene variants that increase risk of nonalcoholic fatty liver disease by different metabolic pathways.

26 Apr 2017

Study reveals promising results for primary liver cancer patients treated with SIR-Spheres Y-90 resin microspheres

Patients with advanced or inoperable Hepatocellular Carcinoma (HCC) who usually received one or two treatments with liver-directed SIR-Spheres Y-90 resin microspheres in the 459-patient French SARAH study had similar survival compared to patients who received standard twice-daily systemic treatment with sorafenib, but with less than half the number and significantly fewer severe treatment-related adverse effects and significantly better Quality of Life, according to data presented here at The International Liver Congress™ 2017.

26 Apr 2017

Enzyme treatment may prevent or reduce liver damage caused by excess alcohol consumption

An intestinal enzyme previously shown to keep bacterial toxins from passing from the gastrointestinal system into the bloodstream may be able to prevent or reduce the liver damage caused by excess alcohol consumption.

25 Apr 2017

Statins may provide favorable outcomes to patients with HBV- or HCV-related cirrhosis

Infection with hepatitis B virus (HBV) or hepatitis C virus (HCV) can lead to cirrhosis as well as liver cancer. A Hepatology study from Taiwan has found that statins may provide benefits to patients with HBV- or HCV-related cirrhosis.

24 Apr 2017

Researchers identify unique bleeding syndrome linked to cirrhosis and portal hypertension

A unique bleeding syndrome associated with cirrhosis and portal hypertension has been identified by researchers at the Medical University of South Carolina, Wake Forest University Medical Center, and the University of Texas Southwestern Medical Center in an article published online on April 21, 2017 by the Journal of Investigative Medicine.

21 Apr 2017

Periodic check-ups are essential to maintain health and longevity of baby boomers

For some baby boomers, getting ready for a routine visit with their doctor is like training for a marathon. Some patients want to be in the best shape possible before stepping on that scale and getting those lab results.

19 Apr 2017

FDA grants approval for two drugs to treat hepatitis C virus in children

The U.S. Food and Drug Administration today approved supplemental applications for Sovaldi (sofosbuvir) and Harvoni (ledipasvir and sofosbuvir) to treat hepatitis C virus (HCV) in children ages 12 to 17. Harvoni and Sovaldi were previously approved to treat HCV in adults.

7 Apr 2017

IBD patients with longer duration of disease have higher risk of developing NAFLD

Research led by a Houston Methodist gastroenterologist shows that patients who have inflammatory bowel disease (IBD) for more than two decades have a higher risk of developing nonalcoholic fatty liver disease (NAFLD).

5 Apr 2017

Magnetic resonance technology can improve fatty liver diagnosis

Taking tissue samples from the liver to diagnose fatty liver can be replaced in most cases by a painless magnetic resonance investigation.

5 Apr 2017

Low and high birth weights linked to severity of liver disease in children

Researchers at University of California San Diego School of Medicine, with a cohort of clinical collaborators from across the United States, have demonstrated the impact of low and high birth weights in developing Non Alcoholic Fatty Liver Disease (NAFLD), a chronic disease that often leads to a need for organ transplantation.

4 Apr 2017

Australia has potential to eradicate hepatitis C in 10–15 years, says expert

Australia has the potential to eradicate hepatitis C in the next 10–15 years, according to Associate Professor Simone Strasser, gastroenterologist at Royal Prince Alfred Hospital in Sydney.

4 Apr 2017

Study shows how early-life BPA exposure leads to NAFLD in adulthood

Exposure during infancy to the common plasticizer bisphenol A "hijacks" and reprograms genes in the liver of newborn rats, leading to nonalcoholic fatty liver disease in adulthood.

2 Apr 2017

Researchers aim to examine therapeutic effect of iPS-ML producing interferon-β on liver cancer

All causes of the most common form of liver cancer, hepatocellular carcinoma, are not yet known, but the risk of getting it is increased by hepatitis B or C, cirrhosis, obesity, diabetes, a buildup of iron in the liver, or a family of toxins called aflatoxins produced by fungi on some types of food.

29 Mar 2017

Loss of partner to suicide may increase risk for mental and physical disorders

People who lose a partner to suicide are at increased risk for a number of mental and physical disorders, including cancer, depression, herniated discs and mood disorders than those in the general population, new Johns Hopkins Bloomberg School of Public Health research suggests.

22 Mar 2017

Study underscores need to increase awareness for HCV testing among baby boomers

A Brief Report appearing in the American Journal of Preventive Medicine looks at testing rates for Hepatitis C virus (HCV) two years after the United States Preventive Services Task Force recommended it for all baby boomers, and finds rates are still very low.

8 Mar 2017

Cirrhosis News and Research

Latest Cirrhosis News and Research

Study shows how probiotic improves integrity of the GI epithelial cell wall in HIV patients

Researchers uncover new mechanism that explains cause of portal hypertension

Infantile spasms and multiple sclerosis relapse data presented at AAN

Study sets stage for potential stool-based test to detect advanced liver fibrosis

Researchers take important step toward using transplanted fetal cells to treat liver failure

Obesity amplifies effects of three risk alleles linked to NAFLD

Study reveals promising results for primary liver cancer patients treated with SIR-Spheres Y-90 resin microspheres

Enzyme treatment may prevent or reduce liver damage caused by excess alcohol consumption

Statins may provide favorable outcomes to patients with HBV- or HCV-related cirrhosis

Researchers identify unique bleeding syndrome linked to cirrhosis and portal hypertension

Periodic check-ups are essential to maintain health and longevity of baby boomers

FDA grants approval for two drugs to treat hepatitis C virus in children

IBD patients with longer duration of disease have higher risk of developing NAFLD

Magnetic resonance technology can improve fatty liver diagnosis

Low and high birth weights linked to severity of liver disease in children

Australia has potential to eradicate hepatitis C in 10–15 years, says expert

Study shows how early-life BPA exposure leads to NAFLD in adulthood

Researchers aim to examine therapeutic effect of iPS-ML producing interferon-β on liver cancer

Loss of partner to suicide may increase risk for mental and physical disorders

Study underscores need to increase awareness for HCV testing among baby boomers

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Cirrhosis News and Research

Latest Cirrhosis News and Research

CellVoyant's AI-Powered Vision for the Future of Cell Therapy

Scalable, Smart, and Accessible: The Future of Lab Automation

Healthy Beginnings, Hopeful Futures: A Conversation with WHO’s Dr. Allotey

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