Cold, Flu & Cough News and Research

Latest Cold, Flu & Cough News and Research

Using Sotrovimab to treat COVID-19 early

A new study published on the medRxiv* preprint server hypothesized that a monoclonal antibody that has the capability to neutralize all sarbecoviruses could also be used to target a highly conserved epitope. This conserved sequence has a high probability of remaining unchanged in SARS-CoV-2 variants.

31 May 2021

Novel protein interactions with ACE2 disrupted by SARS-CoV-2, contributes to COVID-19 pathologies

A severe and often fatal immune response called a “cytokine storm” can occur following SARS-CoV-2 infection. Some patients suffer from a range of complications several months after testing negative for SARS-CoV-2, and this is called ‘Long Haul’ or ‘Long’ COVID-19. The causes behind this phenomenon are not well understood.

31 May 2021

Neuropathology of COVID-19 patients caused by infection of brain pericytes

Recently, researchers from the UK and Sweden used highly sensitive multiplexed immunohistochemistry to study the brain tissue of COVID-19 patients and controls to analyze ACE2 expression in brain pericytes of patients with neurological symptoms. They also used spatial immunophenotyping to assess inflammation in brain tissue of COVID-19 patients.

31 May 2021

A novel multi-epitope COVID-19 vaccine developed using reverse vaccinology

A new study has been published in the Journal of Biomolecular Structure and Dynamics which focuses on the evaluation of E, M, N, ORF10, ORF8, ORF3a, and M proteins using bioinformatics tools to develop a multi-epitope COVID-19 vaccine. The researchers utilized in-silico methods to incite humoral and cellular immune responses.

31 May 2021

Researchers identify defensins as potential anti-SARS-CoV-2 agents

A recent study conducted at the Ohio State University, USA, and the Fudan University, China, has revealed that alpha-defensin human neutrophil peptide 1 (HNP1), a cationic antimicrobial peptide, can prevent severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) from infecting cells by destabilizing the viral spike protein and disrupting spike-mediated viral envelop – host cell membrane fusion.

31 May 2021

A call to action to share 2 billion doses of COVAX in 2021

Countries that are advanced in their vaccination programmes are seeing cases of COVID-19 decline, hospitalizations decrease and early signs of some kind of normality resume.

31 May 2021

Reusing old vaccines to boost innate immunity against COVID-19

The COVID-19 vaccine is currently the best form of protection against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and its variants. But a new perspective article published in the journal PNAS suggests it’s not the panacea to stopping SARS-CoV-2.

31 May 2021

Researchers assess the prognostic value of cardiac troponin I in COVID-19 patients

Corona Virus Disease (COVID -19) patients primarily appear with respiratory issues and viral pneumonia. The patients may also present cardiovascular issues includes early signs of acute myocardial injury.

29 May 2021

FIRS calls on governments and policymakers to support and promote tobacco cessation services

On World No Tobacco Day (31 May, 2021) the Forum of International Respiratory Societies (FIRS), of which the American College of Chest Physicians® (CHEST) is a founding member, calls on governments and policymakers to make greater political and financial commitments to support and promote tobacco cessation services.

29 May 2021

FDA approves targeted therapy for tumors with KRAS mutations

Today, the U.S. Food and Drug Administration approved Lumakras (sotorasib) as the first treatment for adult patients with non-small cell lung cancer whose tumors have a specific type of genetic mutation called KRAS G12C and who have received at least one prior systemic therapy.

29 May 2021

New resolution urges Member States to focus on prevention and management of diabetes, obesity

A new resolution urges Member States to raise the priority given to the prevention, diagnosis and control of diabetes as well as prevention and management of risk factors such as obesity.

29 May 2021

Heart Failure 2021 to showcase latest evidence on prevention, management of heart failure

The latest evidence on the prevention and management of heart failure will be showcased at Heart Failure 2021, an online scientific congress of the European Society of Cardiology (ESC).

29 May 2021

New LNP-based mRNA vaccine candidate protects against lethal SARS-CoV-2 in preclinical trials

A new study, published in Nano Letters, describes an effective new COVID-19 vaccine candidate based on a messenger ribonucleic acid (mRNA) platform.

28 May 2021

Researcher investigates the behavior and life cycle of most infectious pathogenic bacteria

28 May 2021

Study links barotrauma to COVID-19 in younger patients

To better understand the possible relationship between severe infection and poor in-hospital outcomes, researchers from the Internal Medicine, and the Pulmonary Critical Care Medicine, Rutgers University, Newark, USA, presented a case series linking barotrauma to COVID-19 in younger patients.

28 May 2021

Opioids like ‘lean’ permeate hip-hop culture, but dangers are downplayed

Nykerrius Williams knows about the close relationship between hip-hop and opioid use. Williams, 27, an independent rapper from Gibsland, Louisiana, who goes by the name Young Nyke, took oxycodone pills for the first time when he was 16 and has continued patterns of misuse of those pills, as well as Lortabs, Xanax and codeine cough syrups, until recently. To him, it's part of the business.

28 May 2021

Cold, Flu & Cough News and Research

Latest Cold, Flu & Cough News and Research

Using Sotrovimab to treat COVID-19 early

Novel protein interactions with ACE2 disrupted by SARS-CoV-2, contributes to COVID-19 pathologies

Neuropathology of COVID-19 patients caused by infection of brain pericytes

A novel multi-epitope COVID-19 vaccine developed using reverse vaccinology

Researchers identify defensins as potential anti-SARS-CoV-2 agents

A call to action to share 2 billion doses of COVAX in 2021

Reusing old vaccines to boost innate immunity against COVID-19

Researchers assess the prognostic value of cardiac troponin I in COVID-19 patients

FIRS calls on governments and policymakers to support and promote tobacco cessation services

FDA approves targeted therapy for tumors with KRAS mutations

New resolution urges Member States to focus on prevention and management of diabetes, obesity

Heart Failure 2021 to showcase latest evidence on prevention, management of heart failure

New LNP-based mRNA vaccine candidate protects against lethal SARS-CoV-2 in preclinical trials

Researcher investigates the behavior and life cycle of most infectious pathogenic bacteria

Study links barotrauma to COVID-19 in younger patients

Opioids like ‘lean’ permeate hip-hop culture, but dangers are downplayed

Study may lead to new treatments that eliminate cancer cells without harming other body cells

Study explains why it is difficult to withdraw from certain antidepressants

Researchers discover cross-reactive coronavirus antibody triggered during COVID-19 infection

Study shows pertussis is still common among middle-aged adults in European countries

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

Cold, Flu & Cough News and Research

Latest Cold, Flu & Cough News and Research

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

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