Crohn's Disease News and Research

Latest Crohn's Disease News and Research

Cannabis oil shown to significantly improve Crohn’s disease symptoms

In the first study of its kind, cannabis oil has been shown to significantly improve the symptoms of Crohn’s disease and the quality of life of sufferers but, contrary to previous medical thinking, has no effect on gut inflammation.

23 Oct 2018

AbbVie’s U-ACHIEVE Phase 2b/3 dose-ranging study improves outcomes in patients with ulcerative colitis

AbbVie, a research-based global biopharmaceutical company, today announced positive results from U-ACHIEVE, an ongoing Phase 2b/3 dose-ranging study evaluating upadacitinib, an investigational JAK1-selective inhibitor, for induction and maintenance therapy in adult patients with moderately to severely active ulcerative colitis.

23 Oct 2018

Genentech’s combination therapy improves outcome in patients with non-squamous non-small cell lung cancer

Genentech, a member of the Roche Group, today announced positive results from the Phase III IMpower130 study of Tecentriq (atezolizumab) plus chemotherapy (carboplatin and Abraxane® [albumin-bound paclitaxel; nab-paclitaxel]) for the initial (first-line) treatment of people with previously untreated metastatic non-squamous non-small cell lung cancer.

22 Oct 2018

Takeda presents vedolizumab phase 3 VISIBLE 1 trial results for treatment of moderately to severely active ulcerative colitis

Takeda Pharmaceutical Company Limited today announced results from the phase 3 VISIBLE 1 clinical trial evaluating the efficacy and safety of an investigational subcutaneous formulation of the gut-selective biologic vedolizumab for maintenance therapy in adult patients with moderately to severely active ulcerative colitis who achieved clinical response* at week 6 following two doses of open-label vedolizumab intravenous induction therapy.

22 Oct 2018

Pilot clinical trial shows effectiveness of bioelectronic medicine device for lupus

A bioelectronic medicine device was effective in reducing pain and fatigue in patients with lupus, according to Feinstein Institute for Medical Research Professor Cynthia Aranow, MD, who will present pilot clinical trial results Tuesday at the American College of Rheumatology/Association of Rheumatology Professional's Annual Meeting.

22 Oct 2018

Gilead Sciences presents Phase 3 results of filgotinib in biologic-experienced rheumatoid arthritis at 2018 ACR/ARHP Annual Meeting

Gilead Sciences, Inc. and Galapagos NV today announced detailed results from the Phase 3 FINCH 2 clinical trial of filgotinib, an investigational, selective JAK1 inhibitor, in adults with moderately-to-severely active rheumatoid arthritis and prior inadequate response or intolerance to biologic agents.

22 Oct 2018

Study reports increased risk of death in children with inflammatory bowel disease

Children who develop inflammatory bowel disease (ulcerative colitis or Crohn's disease) have an increased risk of death, both in childhood and later in life, a study from Karolinska Institutet in Sweden published in the journal Gastroenterology reports.

19 Oct 2018

Study pinpoints new marker that can predict Crohn’s disease subtype

Crohn's disease, a chronic inflammatory condition of the intestinal tract, has emerged as a global disease, with rates steadily increasing over the last 50 years.

16 Oct 2018

Study reveals factors linked to the development of Crohn's disease

How cells talk to each other, and what they say, has long held fascination for Seema Khurana, professor of biology and biochemistry.

5 Oct 2018

Understanding immune system's balancing act could help in prevention, treatment of IBD

Australian researchers have uncovered clues in the immune system that reveal how the balance of 'good' gut bacteria is maintained. This information could help in the prevention and treatment of inflammatory bowel disease.

3 Oct 2018

Finding epigenetic signature appears to predict inflammation risk in serious type of IBD

With an estimated 1.6 million people in the U.S. dealing with inflammatory bowel disease (IBD), physicians can have a hard time telling which newly diagnosed patients have a high risk of severe inflammation or what therapies will be most effective.

20 Sep 2018

Fiber strengthens intestinal barrier and counteracts gastrointestinal problems

Similar to patients with Crohn's disease, elderly people with stomach problems have a intestinal barrier that is not functioning optimally.

7 Sep 2018

TGHRI scientists detail role of insulin as a boost to the immune system

The role of insulin as a boost to the immune system to improve its ability to fight infection has been detailed for the first time by Toronto General Hospital Research Institute scientists.

30 Aug 2018

New lung tissue-on-a-chip system offers rapid testing of potential anti-fibrotic treatments

Pulmonary fibrosis is one of the most common and serious types of lung disease. Now NIBIB-funded researchers have developed an in vitro lung tissue-on-a-chip system that mimics lung fibrosis, offering rapid testing of potential new anti-fibrotic treatments.

28 Aug 2018

Experts examine stool protein biomarkers that indicate inflammatory bowel disease

University of Houston researcher Chandra Mohan is set to make a breakthrough in predicting and monitoring inflammatory bowel disease.

21 Aug 2018

Strawberries could mitigate colonic inflammation

Inflammatory bowel disease is a set of painful conditions that can cause severe diarrhea and fatigue. Treatments can include medications and surgery. But now researchers report that a simple dietary intervention could mitigate colonic inflammation and improve gut health.

20 Aug 2018

New approach identifies genes that help microbes to survive in the human gut

Trillions of tiny microbes and bacteria live in your gut, each with their own set of genes. These gut microbes can have both beneficial and harmful effects on your health, from protecting you against inflammation to causing life-threatening infections.

10 Aug 2018

Crohn's Disease News and Research

Latest Crohn's Disease News and Research

Cannabis oil shown to significantly improve Crohn’s disease symptoms

AbbVie’s U-ACHIEVE Phase 2b/3 dose-ranging study improves outcomes in patients with ulcerative colitis

Genentech’s combination therapy improves outcome in patients with non-squamous non-small cell lung cancer

Takeda presents vedolizumab phase 3 VISIBLE 1 trial results for treatment of moderately to severely active ulcerative colitis

Pilot clinical trial shows effectiveness of bioelectronic medicine device for lupus

Gilead Sciences presents Phase 3 results of filgotinib in biologic-experienced rheumatoid arthritis at 2018 ACR/ARHP Annual Meeting

Study reports increased risk of death in children with inflammatory bowel disease

Study pinpoints new marker that can predict Crohn’s disease subtype

Study reveals factors linked to the development of Crohn's disease

Understanding immune system's balancing act could help in prevention, treatment of IBD

Finding epigenetic signature appears to predict inflammation risk in serious type of IBD

Fiber strengthens intestinal barrier and counteracts gastrointestinal problems

TGHRI scientists detail role of insulin as a boost to the immune system

New lung tissue-on-a-chip system offers rapid testing of potential anti-fibrotic treatments

Experts examine stool protein biomarkers that indicate inflammatory bowel disease

Strawberries could mitigate colonic inflammation

New approach identifies genes that help microbes to survive in the human gut

Clinical trial to use stem cell transplants for treating Crohn's disease

Penn Medicine receives federal government approval to develop imaging guidelines

Researchers discover new protein that controls level of inflammation-inducing molecule

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

Crohn's Disease News and Research

Latest Crohn's Disease News and Research

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

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