Crohn's Disease News and Research

Latest Crohn's Disease News and Research

RedHill Biopharma initiates phase II study of BEKINDA for irritable bowel syndrome

RedHill Biopharma Ltd. (NASDAQ; RDHL) (TASE: RDHL) (“RedHill” or the “Company”), a biopharmaceutical company primarily focused on development and commercialization of late clinical-stage, proprietary, orally-administered, small molecule drugs for inflammatory and gastrointestinal diseases, including cancer, today announced that it has initiated a randomized, double-blind, 2-arm parallel group Phase II clinical study in the U.S. evaluating the safety and efficacy of BEKINDA™ 12 mg in patients with diarrhea-predominant irritable bowel syndrome (IBS-D).

13 Apr 2016

Bacteria uses sensitive, nano-sized pump to transport magnesium

Researchers at UiO and NCMM have discovered that the system used by bacteria to transport magnesium is so sensitive that it can detect a pinch of magnesium salt in a swimming pool.

7 Apr 2016

Children of salmon-eating mothers less likely to develop asthma

Children born to mothers who eat salmon when pregnant may be less likely to have doctor diagnosed asthma compared to children whose mothers do not eat it, new research has shown.

6 Apr 2016

Inflectra (infliximab-dyyb) approved for multiple indications

The U.S. Food and Drug Administration today approved Inflectra (infliximab-dyyb) for multiple indications. Inflectra is administered by intravenous infusion. This is the second biosimilar approved by the FDA.

6 Apr 2016

Smoking drastically alters oral microbiome, study finds

Smoking drastically alters the oral microbiome, the mix of roughly 600 bacterial species that live in people's mouths. This is the finding of a study led by NYU Langone Medical Center and its Laura and Isaac Perlmutter Cancer Center to be published online March 25 in the ISME (International Society for Microbial Ecology) Journal.

30 Mar 2016

Global research links genes to five common, hard-to-treat inflammatory diseases

A global study involving 50 different research centres has found hundreds of genes which cause five common, hard-to-treat and debilitating inflammatory diseases, paving the way to new treatments for these conditions

16 Mar 2016

Secretory capacity of human gut does not decline with age, shows study

A breakthrough in basic research and the first comprehensive study on the secretory activity of the human intestine: over a period of eight years, Dr. Dagmar Krüger of the Department of Human Biology at TU Munich has examined more than 2200 specimens from around 450 patients with bowel disease.

10 Mar 2016

Incidence of IBD much higher in Rhode Island

A study led by the Hasbro Children's Hospital Division of Pediatric Gastroenterology, Nutrition and Liver Diseases found that the incidence of inflammatory bowel disease (IBD) in Rhode Island is one of the highest ever reported in the United States and that IBD rates nationally are much higher than previously reported.

4 Mar 2016

Current DRG-based cost recovery system appears problematic for patients with complex disorders

A new study by researchers from Charité - Universitätsmedizin Berlin compares the true cost of treating patients with chronic inflammatory bowel disease with costs recoverable under the current German DRG-based system.

24 Feb 2016

Study highlights dual role of cytokine in inflammatory bowel disease

Small proteins that affect communication between cells play an important role in regulating inflammation that occurs during inflammatory bowel disease, according to researchers at Georgia State University, Emory University, the University of Michigan and Amgen, a biotechnology company.

17 Feb 2016

Research findings identify potential genetics-guided precision medicine for leukemia patients

An international research team has determined how inherited gene variations lead to severe drug toxicity that may threaten chances for a cure in children with leukemia. St. Jude Children's Research Hospital scientists led the study, results of which set the stage to expand the use of a patient's genetic make-up to tailor chemotherapy.

16 Feb 2016

Remicade co-developer funds new microscopy facility on Scripps Florida campus

The co-developer of Remicade, one of the three top-selling drugs in the world, has donated more than $500,000 to fund what will be known as the Iris and Junming Le Foundation Super-Resolution Microscopy Facility on the Florida campus of The Scripps Research Institute.

30 Jan 2016

Scientists solve atomic structure of ubiquitin ligase complex that plays key role in protein degradation

Scientists at Sanford Burnham Prebys Medical Discovery Institute have solved the atomic structure of a unique ubiquitin ligase complex. Ubiquitin is best known for its role in protein degradation, but more recently seen as important for cell signaling, DNA repair, anti-inflammatory, and immune responses.

21 Jan 2016

Novartis announces FDA approval of Cosentyx for treatment of adult patients with AS and PsA

Novartis announced today that the US Food and Drug Administration has approved Cosentyx (secukinumab) for two new indications - the treatment of adult patients with active ankylosing spondylitis (AS) and active psoriatic arthritis (PsA).

17 Jan 2016

Chromoendoscopy superior to other surveillance methods in detecting dysplasia in IBD patients

Chromoendoscopy is superior to random biopsy or white-light colonoscopy in detecting dysplasia in patients with inflammatory bowel diseases (IBD), according to a long-term surveillance study led by James F. Marion, MD, Professor of Medicine at Icahn School of Medicine at Mount Sinai, and Director of Education and Outreach at The Susan and Leonard Feinstein Inflammatory Bowel Disease Clinical Center at The Mount Sinai Hospital, published online in the journal Clinical Gastroenterology and Hepatology.

11 Jan 2016

Processed foods may increase likelihood of developing autoimmune diseases

In today's hustle and bustle world, processed foods are commonplace time-savers. But that convenience factor may come with a bigger price tag than previously known, says an international team of researchers.

31 Dec 2015

Immune enters into exclusive license with Atlante Biotech for new format of bispecific antibodies

Immune Pharmaceuticals Inc. a clinical-stage company developing novel therapies for the treatment of immuno-inflammatory diseases and cancer, today announced it has entered into an exclusive license with Atlante Biotech SAS, to the patents and know-how for a new format of bispecific antibodies.

29 Dec 2015

NEJM publishes results of Cosentyx Phase III studies in ankylosing spondylitis

Novartis announced today that the results of the MEASURE 1 and MEASURE 2 Phase III studies for Cosentyx® (secukinumab) in ankylosing spondylitis (AS) were published in The New England Journal of Medicine (NEJM). These pivotal studies demonstrated significant clinical improvements with Cosentyx versus placebo in reducing the signs and symptoms of active AS – a long-term, painful and debilitating inflammation of the spine.

24 Dec 2015

Stem cell therapy not significantly better than conventional treatment for Crohn's disease

A clinical trial to test the effectiveness of a stem cell therapy among adults with difficult to treat Crohn's disease has found it is not significantly better than conventional treatment in producing sustained disease remission after one year.

18 Dec 2015

Acupuncture may be safe, effective treatment for chronic pain in pediatric patients

It is upsetting to see anyone in pain, but it's especially heartbreaking to watch a child endure chronic pain. In addition to the suffering itself, chronic pain can cause traumatic effects on a child's quality of life, and it can have significant physical, psychological and social consequences. Making matters worse, chronic pain greatly can affect the child's parents or caregivers by causing feelings of helplessness and inadequacy.

16 Dec 2015

Crohn's Disease News and Research

Latest Crohn's Disease News and Research

RedHill Biopharma initiates phase II study of BEKINDA for irritable bowel syndrome

Bacteria uses sensitive, nano-sized pump to transport magnesium

Children of salmon-eating mothers less likely to develop asthma

Inflectra (infliximab-dyyb) approved for multiple indications

Smoking drastically alters oral microbiome, study finds

Global research links genes to five common, hard-to-treat inflammatory diseases

Secretory capacity of human gut does not decline with age, shows study

Incidence of IBD much higher in Rhode Island

Current DRG-based cost recovery system appears problematic for patients with complex disorders

Study highlights dual role of cytokine in inflammatory bowel disease

Research findings identify potential genetics-guided precision medicine for leukemia patients

Remicade co-developer funds new microscopy facility on Scripps Florida campus

Scientists solve atomic structure of ubiquitin ligase complex that plays key role in protein degradation

Novartis announces FDA approval of Cosentyx for treatment of adult patients with AS and PsA

Chromoendoscopy superior to other surveillance methods in detecting dysplasia in IBD patients

Processed foods may increase likelihood of developing autoimmune diseases

Immune enters into exclusive license with Atlante Biotech for new format of bispecific antibodies

NEJM publishes results of Cosentyx Phase III studies in ankylosing spondylitis

Stem cell therapy not significantly better than conventional treatment for Crohn's disease

Acupuncture may be safe, effective treatment for chronic pain in pediatric patients

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Crohn's Disease News and Research

Latest Crohn's Disease News and Research

CellVoyant's AI-Powered Vision for the Future of Cell Therapy

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Healthy Beginnings, Hopeful Futures: A Conversation with WHO’s Dr. Allotey

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