Crohn's Disease News and Research

Latest Crohn's Disease News and Research

JBCPP journal publishes new evidence for clinical efficacy of cannabis therapy

New evidence for the clinical efficacy of cannabis therapy is presented in the latest issue of the Journal of Basic and Clinical Physiology and Pharmacology, a De Gruyter publication.

23 May 2016

Scientists take key step towards understanding link between obesity and physically distant diseases

Obesity is on the rise throughout the world, and in some developed countries two-third of the adult population is either overweight or obese. This brings with it an increased risk of serious conditions such as heart disease, stroke, cancer and osteoarthritis.

23 May 2016

Penn State researchers link mutation in common virus to fatal brain disease

Why people on immunosuppressant drugs for autoimmune conditions have a higher incidence of an often-fatal brain disease may be linked to a mutation in a common virus, according to researchers at Penn State College of Medicine.

19 May 2016

Maintaining balance of P1 and P2 isoforms vital for reducing colon cancer, colitis risk

Inflammatory bowel disease (IBD), of which Crohn's disease and ulcerative colitis are the main types, is on the increase in the United States, affecting more than 1.6 million people and explaining perhaps the increase in advertisements offering treatments and cures.

18 May 2016

Caltech researchers discover new potential cause for Crohn's disease

The community of beneficial bacteria that live in our intestines, known as the gut microbiome, are important for the development and function of the immune system. There has been growing evidence that certain probiotics--therapies that introduce beneficial bacteria into the gut--may help alleviate some of the symptoms of intestinal disorders such as Crohn's disease.

10 May 2016

Genetic variations that prevent beneficial gut bacteria from working may lead to Crohn's disease

A major type of inflammatory bowel disease (IBD) may be caused in part by genetic variants that prevent beneficial bacteria in the gut from doing their job, according to a new study published today in the journal Science.

6 May 2016

Serum biomarkers can help predict risk of IBD development and complications

Years before inflammatory bowel disease (IBD) is diagnosed and symptoms exist, biomarkers are already circulating that can help predict risk not only of disease development but also of complications, according to research published online last week, which will also appear in the June 15th print issue of Alimentary Pharmacology & Therapeutics.

6 May 2016

Certain sugars in the body play key role in colitis, colon cancer development

An Oklahoma Medical Research Foundation scientist has discovered that certain sugars produced by the body play an important role in the development of colitis and, ultimately, colon cancer. The new finding could potentially lead to therapies for ulcerative colitis, Crohn's disease and colon cancer.

5 May 2016

Promising specialty medical home approach to patient-centered, cost-effective care for IBD patients

A specialty medical home--providing expert medical care coordinated with attention to social support and mental health--is a promising new approach to patient-centered, cost-effective care for patients with Crohn's disease and ulcerative colitis, according to a special "Future Directions" paper in the May issue of Inflammatory Bowel Diseases, official journal of the Crohn's & Colitis Foundation of America. The journal is published by Wolters Kluwer.

5 May 2016

CMGH study offers insight into future interventions for Crohn's disease, chronic pancreatitis

Cellular and Molecular Gastroenterology and Hepatology is committed to publishing impactful digestive biology research covering a broad spectrum of themes in GI, hepatology and pancreatology. We wanted to share two new CMGH articles, which both offer important insight into future interventions for chronic conditions.

30 Apr 2016

ATR-FTIR spectroscopy could be effective for detecting ulcerative colitis

A minimally invasive screening for ulcerative colitis, a debilitating gastrointestinal tract disorder, using emerging infrared technology could be a rapid and cost-effective method for detecting disease that eliminates the need for biopsies and intrusive testing of the human body, according to researchers at Georgia State University.

27 Apr 2016

TNF-alpha protein involved in autoimmune diseases may also promote tissue healing

As its name suggests, inflammatory bowel disease, which afflicts more than 1.6 million Americans, involves chronic inflammation of all or some of the digestive tract. An autoimmune disease known to have a strong genetic component, its symptoms are abdominal cramps, bloody diarrhea, and fever and, sometimes, weight loss. IBD, which is a group of inflammatory conditions, includes Crohn's disease and ulcerative colitis.

21 Apr 2016

RedHill Biopharma initiates phase II study of BEKINDA for irritable bowel syndrome

RedHill Biopharma Ltd. (NASDAQ; RDHL) (TASE: RDHL) (“RedHill” or the “Company”), a biopharmaceutical company primarily focused on development and commercialization of late clinical-stage, proprietary, orally-administered, small molecule drugs for inflammatory and gastrointestinal diseases, including cancer, today announced that it has initiated a randomized, double-blind, 2-arm parallel group Phase II clinical study in the U.S. evaluating the safety and efficacy of BEKINDA™ 12 mg in patients with diarrhea-predominant irritable bowel syndrome (IBS-D).

13 Apr 2016

Bacteria uses sensitive, nano-sized pump to transport magnesium

Researchers at UiO and NCMM have discovered that the system used by bacteria to transport magnesium is so sensitive that it can detect a pinch of magnesium salt in a swimming pool.

7 Apr 2016

Children of salmon-eating mothers less likely to develop asthma

Children born to mothers who eat salmon when pregnant may be less likely to have doctor diagnosed asthma compared to children whose mothers do not eat it, new research has shown.

6 Apr 2016

Inflectra (infliximab-dyyb) approved for multiple indications

The U.S. Food and Drug Administration today approved Inflectra (infliximab-dyyb) for multiple indications. Inflectra is administered by intravenous infusion. This is the second biosimilar approved by the FDA.

6 Apr 2016

Smoking drastically alters oral microbiome, study finds

Smoking drastically alters the oral microbiome, the mix of roughly 600 bacterial species that live in people's mouths. This is the finding of a study led by NYU Langone Medical Center and its Laura and Isaac Perlmutter Cancer Center to be published online March 25 in the ISME (International Society for Microbial Ecology) Journal.

30 Mar 2016

Global research links genes to five common, hard-to-treat inflammatory diseases

A global study involving 50 different research centres has found hundreds of genes which cause five common, hard-to-treat and debilitating inflammatory diseases, paving the way to new treatments for these conditions

16 Mar 2016

Secretory capacity of human gut does not decline with age, shows study

A breakthrough in basic research and the first comprehensive study on the secretory activity of the human intestine: over a period of eight years, Dr. Dagmar Krüger of the Department of Human Biology at TU Munich has examined more than 2200 specimens from around 450 patients with bowel disease.

10 Mar 2016

Incidence of IBD much higher in Rhode Island

A study led by the Hasbro Children's Hospital Division of Pediatric Gastroenterology, Nutrition and Liver Diseases found that the incidence of inflammatory bowel disease (IBD) in Rhode Island is one of the highest ever reported in the United States and that IBD rates nationally are much higher than previously reported.

4 Mar 2016