Crohn's Disease News and Research

Latest Crohn's Disease News and Research

Injectable hydrogel composite loaded with stem cells shows success in treating perianal fistulas

In a new study using a rat model of Crohn's disease, a biodegradable hydrogel composite loaded with stem cells, developed by Johns Hopkins Medicine researchers, in a collaborative effort with the Whiting School of Engineering, has shown significant success in treating perianal fistulas (PAF) — one of the many complications of Crohn's disease.

25 Jan 2023

Women’s inequitable healthcare experiences reflect implicit bias, discrimination and disempowerment

For some women who experience serious and chronic physical or mental health conditions, one of their most daunting challenges is obtaining the belief and validation of health care providers, family members and friends, researchers found in a recent study.

20 Dec 2022

Study shows common synthetic food dye as a potential dietary trigger for IBDs

Long-term consumption of Allura Red food dye can be a potential trigger of inflammatory bowel diseases (IBDs), Crohn's disease and ulcerative colitis, says McMaster University's Waliul Khan.

20 Dec 2022

Four genetic mutations linked to progressive multifocal leukoencephalopathy

New research has confirmed a strong link between four genetic mutations and progressive multifocal leukoencephalopathy (PML), a rare but often fatal brain infection that can be triggered by dozens of FDA-approved drugs.

14 Dec 2022

Strong connection between inflammatory bowel disease and periodontitis

Inflammatory bowel disease often coexists with periodontal disease. This is shown by new publications from a European research project that explored the connection between the two diseases.

13 Dec 2022

How human cell atlases provide the missing links between genes, diseases and therapies

A Nature Medicine journal perspective article describes the potential of cell atlases in shaping the future of medicine. Providing the missing link between genes and diseases, single-cell atlases make it possible to develop more precise and specific diagnostic tools by understanding the mechanisms of complex diseases.

12 Dec 2022

Sharp increase in B cell population can prevent intestinal healing

B cells are critical to the proper functioning of the immune system. However, researchers at Karolinska Institutet have shown that they can sometimes do more harm than good, as their numbers greatly increase after bowel damage, preventing the tissue from healing.

2 Dec 2022

Harmful gut bacteria co-opt a genetic susceptibility to trigger Crohn’s disease

Changes in a single gene open the door for harmful gut bacteria to set off the inflammation that drives Crohn’s disease, according to a new study led by Weill Cornell Medicine and NewYork-Presbyterian investigators.

1 Dec 2022

Biologic therapy for IBD patients through a financial assistance program could have superior outcomes

Patients with inflammatory bowel diseases (IBD) who required treatment with biologic therapies and were enrolled in a financial assistance program were less likely to need surgery after starting medication than those not enrolled in a program, a study by UT Southwestern researchers found.

23 Nov 2022

The antimicrobial activity of tee tree oil nanoliposomes against Escherichia coli

The main aim of the current study is to develop a new drug to promote sustainable and healthy animal husbandry in China.

18 Nov 2022

Defense department health plan cuts its pharmacy network by nearly 15,000 outlets

Doris Spatz takes a once-a-day pill, Kisqali, to keep her metastatic breast cancer in check. As a patient in the Defense Department health system, she can fill routine prescriptions at a military pharmacy without a copay but also has the option of using a regular pharmacy through Tricare, the Defense Department's private health care program.

8 Nov 2022

New insights into the dynamic inner world of the human immune system

As researchers glean new insights into the dynamic inner world of the human immune system, it has become increasingly clear that mitochondria are critical regulators of how our bodies respond to disease.

3 Nov 2022

Research opens up new avenues for overcoming treatment resistance in colorectal cancer

Colorectal cancer is one of the most common cancers. Its treatment is mainly based on chemotherapy. However, over time, chemotherapy induces resistance in the majority of patients, who end up being unresponsive to the drugs.

27 Oct 2022

Pain-sensing neurons protect the gut from inflammation and associated tissue damage

Neurons that sense pain protect the gut from inflammation and associated tissue damage by regulating the microbial community living in the intestines, according to a study from researchers at Weill Cornell Medicine.

14 Oct 2022

Study may have solved a mystery surrounding Crohn’s disease

A new study may have solved a mystery surrounding Crohn's disease, a type of inflammatory bowel disease in which immune defenses meant to attack invading microbes instead mistakenly target the body's own digestive tract.

5 Oct 2022

Study suggests the immune system may benefit from a measure of stress

Stress has been linked to all sorts of serious health issues, from insomnia to high blood pressure, obesity and even heart disease. But it's generally acknowledged that some stress can also be helpful, like when someone's chasing a work deadline.

28 Sep 2022

Researchers show how mucus protects the small intestine in mice

Researchers at the University of Gothenburg have now shown how mucus protects the small intestine in mice. In the future, this finding may lead to new ways of preventing relapse in Crohn’s disease in humans.

23 Sep 2022

First-of-its-kind messenger RNA therapy developed for ovarian cancer, cachexia

Researchers at Oregon State University and Oregon Health & Science University have developed a promising, first-of-its-kind messenger RNA therapy for ovarian cancer as well as cachexia, a muscle-wasting condition associated with cancer and other chronic illnesses.

13 Sep 2022

New data analysis approach could help uncover the genetic basis of many diseases

In the era of Big Data, obtaining a huge amount of information is the easy part; knowing what to do with it is another story entirely.

9 Sep 2022

Discovery sheds light on an important aspect of gut health and mucosal immunity

Immune cells called group 3 innate lymphoid cells (ILC3s) play an essential role in establishing tolerance to symbiotic microbes that dwell in the human gastrointestinal tract, according to a study led by researchers at Weill Cornell Medicine.

7 Sep 2022

Crohn's Disease News and Research

Latest Crohn's Disease News and Research

Injectable hydrogel composite loaded with stem cells shows success in treating perianal fistulas

Women’s inequitable healthcare experiences reflect implicit bias, discrimination and disempowerment

Study shows common synthetic food dye as a potential dietary trigger for IBDs

Four genetic mutations linked to progressive multifocal leukoencephalopathy

Strong connection between inflammatory bowel disease and periodontitis

How human cell atlases provide the missing links between genes, diseases and therapies

Sharp increase in B cell population can prevent intestinal healing

Harmful gut bacteria co-opt a genetic susceptibility to trigger Crohn’s disease

Biologic therapy for IBD patients through a financial assistance program could have superior outcomes

The antimicrobial activity of tee tree oil nanoliposomes against Escherichia coli

Defense department health plan cuts its pharmacy network by nearly 15,000 outlets

New insights into the dynamic inner world of the human immune system

Research opens up new avenues for overcoming treatment resistance in colorectal cancer

Pain-sensing neurons protect the gut from inflammation and associated tissue damage

Study may have solved a mystery surrounding Crohn’s disease

Study suggests the immune system may benefit from a measure of stress

Researchers show how mucus protects the small intestine in mice

First-of-its-kind messenger RNA therapy developed for ovarian cancer, cachexia

New data analysis approach could help uncover the genetic basis of many diseases

Discovery sheds light on an important aspect of gut health and mucosal immunity

Scalable, Smart, and Accessible: The Future of Lab Automation

Healthy Beginnings, Hopeful Futures: A Conversation with WHO’s Dr. Allotey

The evolution of OCT for retinal imaging and disease intervention

Crohn's Disease News and Research

Latest Crohn's Disease News and Research

Scalable, Smart, and Accessible: The Future of Lab Automation

Healthy Beginnings, Hopeful Futures: A Conversation with WHO’s Dr. Allotey

The evolution of OCT for retinal imaging and disease intervention

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