Crohn's Disease News and Research

Latest Crohn's Disease News and Research

Two-drug combination may offer a new way to treat inflammatory bowel diseases, study suggests

Fresh insights into how our bodies interact with the microbes living in our guts suggest that a two-drug combination may offer a new way to treat inflammatory bowel diseases such as Crohn's disease and ulcerative colitis.

4 Apr 2023

Clinical trial findings may be a game changer in the treatment of pediatric Crohn's disease

Crohn's disease is a lifelong inflammatory bowel disease (IBD) that is characterized by swelling in the lining of the digestive tract, causing severe diarrhea, abdominal pain, and rectal bleeding.

3 Apr 2023

Vedolizumab found to be effective for the treatment of chronic pouchitis after colectomy

12% of people with ulcerative colitis need surgery to have their colon removed (colectomy). Most of those have an ileo-anal pouch surgically constructed from their small bowel, which means that they don't have to live with a stoma bag.

31 Mar 2023

An apple a day keeps the doctor away: polyphenol-enriched apples alter immune cell gene expression and fecal microbiota composition

Researchers compared the effects of consuming red-fleshed apples and white-fleshed among healthy adults.

29 Mar 2023

What role does dysbiosis play in Parkinson's disease?

The current study, published in the journal Revue Neurologique, is based on the hypothesis that dysbiosis, or unhealthy variations in the gut and oral microbiota, is a key component of PD pathogenesis.

19 Mar 2023

An expert from Yale Cancer Center discusses colorectal cancer among young people, screening guidelines, and more

Michael Cecchini, MD, Yale Cancer Center medical oncologist specializing in gastrointestinal cancers, is available to discuss several topics during colorectal cancer awareness month.

2 Mar 2023

Digital twins can lead to more personalized drug therapies for inflammatory diseases

Inflammatory diseases like rheumatoid arthritis have complex disease mechanisms that can differ from patient to patient with the same diagnosis.

28 Feb 2023

Can the gut microbiota and metabolome explain variation in anti-SARS-CoV-2 vaccination responses in immunosuppressed IBD patients?

Researchers explored the connection between the metabolic function of the gut microbiota, its composition, and immune response to SARS-CoV-2 vaccination in IBD patients.

27 Feb 2023

Present-day humans share stronger genetic ties with Neanderthals than previously thought

Like a merchant of old, balancing the weights of two different commodities on a scale, nature can keep different genetic traits in balance as a species evolves over millions of years.

21 Feb 2023

AGA recommends non-invasive biomarkers as first-line strategy for monitoring ulcerative colitis

In new evidence-based guidelines, the American Gastroenterological Association recommends non-invasive biomarkers as a first-line strategy for monitoring many patients with ulcerative colitis (UC).

21 Feb 2023

New technique allows researchers to record activity of the enteric nervous system in mice

University of Calgary researchers designed a novel imaging and experimental preparation system, allowing them to record the activity of the enteric nervous system in mice.

16 Feb 2023

Scientists receive $2.9 million NIH grant to better understand the genetics of IBD in Hispanics

After studying the genetic sequences of more than 100,000 people, researchers around the country have started to uncover the root causes of inflammatory bowel disease (IBD), Crohn's disease, and ulcerative colitis.

26 Jan 2023

Injectable hydrogel composite loaded with stem cells shows success in treating perianal fistulas

In a new study using a rat model of Crohn's disease, a biodegradable hydrogel composite loaded with stem cells, developed by Johns Hopkins Medicine researchers, in a collaborative effort with the Whiting School of Engineering, has shown significant success in treating perianal fistulas (PAF) — one of the many complications of Crohn's disease.

25 Jan 2023

Women’s inequitable healthcare experiences reflect implicit bias, discrimination and disempowerment

For some women who experience serious and chronic physical or mental health conditions, one of their most daunting challenges is obtaining the belief and validation of health care providers, family members and friends, researchers found in a recent study.

20 Dec 2022

Study shows common synthetic food dye as a potential dietary trigger for IBDs

Long-term consumption of Allura Red food dye can be a potential trigger of inflammatory bowel diseases (IBDs), Crohn's disease and ulcerative colitis, says McMaster University's Waliul Khan.

20 Dec 2022

Four genetic mutations linked to progressive multifocal leukoencephalopathy

New research has confirmed a strong link between four genetic mutations and progressive multifocal leukoencephalopathy (PML), a rare but often fatal brain infection that can be triggered by dozens of FDA-approved drugs.

14 Dec 2022

Strong connection between inflammatory bowel disease and periodontitis

Inflammatory bowel disease often coexists with periodontal disease. This is shown by new publications from a European research project that explored the connection between the two diseases.

13 Dec 2022

How human cell atlases provide the missing links between genes, diseases and therapies

A Nature Medicine journal perspective article describes the potential of cell atlases in shaping the future of medicine. Providing the missing link between genes and diseases, single-cell atlases make it possible to develop more precise and specific diagnostic tools by understanding the mechanisms of complex diseases.

12 Dec 2022

Sharp increase in B cell population can prevent intestinal healing

B cells are critical to the proper functioning of the immune system. However, researchers at Karolinska Institutet have shown that they can sometimes do more harm than good, as their numbers greatly increase after bowel damage, preventing the tissue from healing.

2 Dec 2022

Harmful gut bacteria co-opt a genetic susceptibility to trigger Crohn’s disease

Changes in a single gene open the door for harmful gut bacteria to set off the inflammation that drives Crohn’s disease, according to a new study led by Weill Cornell Medicine and NewYork-Presbyterian investigators.

1 Dec 2022

Crohn's Disease News and Research

Latest Crohn's Disease News and Research

Two-drug combination may offer a new way to treat inflammatory bowel diseases, study suggests

Clinical trial findings may be a game changer in the treatment of pediatric Crohn's disease

Vedolizumab found to be effective for the treatment of chronic pouchitis after colectomy

An apple a day keeps the doctor away: polyphenol-enriched apples alter immune cell gene expression and fecal microbiota composition

What role does dysbiosis play in Parkinson's disease?

An expert from Yale Cancer Center discusses colorectal cancer among young people, screening guidelines, and more

Digital twins can lead to more personalized drug therapies for inflammatory diseases

Can the gut microbiota and metabolome explain variation in anti-SARS-CoV-2 vaccination responses in immunosuppressed IBD patients?

Present-day humans share stronger genetic ties with Neanderthals than previously thought

AGA recommends non-invasive biomarkers as first-line strategy for monitoring ulcerative colitis

New technique allows researchers to record activity of the enteric nervous system in mice

Scientists receive $2.9 million NIH grant to better understand the genetics of IBD in Hispanics

Injectable hydrogel composite loaded with stem cells shows success in treating perianal fistulas

Women’s inequitable healthcare experiences reflect implicit bias, discrimination and disempowerment

Study shows common synthetic food dye as a potential dietary trigger for IBDs

Four genetic mutations linked to progressive multifocal leukoencephalopathy

Strong connection between inflammatory bowel disease and periodontitis

How human cell atlases provide the missing links between genes, diseases and therapies

Sharp increase in B cell population can prevent intestinal healing

Harmful gut bacteria co-opt a genetic susceptibility to trigger Crohn’s disease

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

Crohn's Disease News and Research

Latest Crohn's Disease News and Research

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

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