Gene News and Research

Latest Gene News and Research

DNA imaging suggests where lung cancer genes may reside

With equipment designed to probe the smallest segments of the genetic code, researchers at Dana-Farber Cancer Institute and collaborating institutions have found sections of the chromosomes of lung cancer cells where cancer-related genes may lurk.

4 Jul 2005

Researchers use imaging to gain better understanding of cancerous cell behaviour

Thanks to imaging and analysis techniques used by researchers at TU Delft, an international group of scientists has been able to gain more insight into the behaviour of cancerous cells.

30 Jun 2005

Researchers find enzyme vital for controlling the early stages of cell death

Researchers at UT Southwestern Medical Center have found an enzyme vital for controlling the early stages of cell death - a beneficial and normal process when it works right, but malignant in a variety of cancers when it malfunctions.

30 Jun 2005

Scientists discover identifying markers for primitive blood-forming stem cells - simplifies cell identification

Scientists at the University of Michigan Medical School have discovered the biological equivalent of a grocery store bar code on the surface of primitive, blood-forming stem cells in mice. Called hematopoietic stem cells, they give rise to all the different types of specialized cells found in blood.

30 Jun 2005

Protein that was thought to simply turn genes on and off now looks to be more like a cellular dimmer switch

The scientists showed for the first time that when certain parts of a protein molecule are modified - flexible, randomly structured regions believed to be only minor players in the protein world - they become important in turning genes on and off, but in a way that resembles a dimmer switch rather than an on-off switch.

30 Jun 2005

Researchers have identified a highly specific pathway that causes inflammation in lung tissue

...a discovery that could help in the design of more targeted treatments for patients with various lung diseases, including cystic fibrosis.

30 Jun 2005

Map of gene control regions provides tool for understanding cells' different roles

In another step to decipher information in the human genome, scientists have discovered the location and sequence of over 10,000 DNA regions that function as genetic on-off switches, or "promoters" in human fibroblasts.

29 Jun 2005

Exercise helps find genetic regions linked to prediabetes

People's bodies respond to exercise in different ways, and their genetic makeup is partly responsible.

28 Jun 2005

New clues about the location of genes potentially involved in the most common type of lung cancer

Using technology that makes it possible to zoom in on smaller sections of cell chromosomes than ever before, researchers at Dana-Farber Cancer Institute have identified nearly 100 chromosome regions where genes are either over-copied or missing in non-small cell lung cancer.

27 Jun 2005

Study causes big shift in how we think about p53 gene

The cellular cascade of molecular signals that instructs cells with fatally damaged DNA to self-destruct pivots on the p53 tumor suppressor gene. If p53 is inactivated, as it is in over half of all human cancers, checks and balances on cell growth fail to operate, and body cells start to accumulate mutations, which ultimately may lead to cancer.

27 Jun 2005

Researchers successfully treat laboratory model of a lysosomal storage disease called GM1

Physicians might one day be able to treat a disease that destroys brain cells in children using genetically modified cells to transport a "drug" to the site of the dying neural cells (cells that transmit impulses).

27 Jun 2005

If you know how viruses get into cells, you know how to better design drugs to keep them out

When it comes to gaining entry into cells, size matters. A team from Brown University and the Max Planck Institute for Metals Research has created a model that explains how viruses and other bioparticles slip inside cells without a special protein coating called clathrin.

27 Jun 2005

Technique called phylogenetic footprinting reveals new gene regulation system

By comparing 140 sequenced bacterial genomes, researchers have uncovered a system for regulating genes essential to bacterial replication - and they did it solely by computer keystrokes and mouse clicks.

27 Jun 2005

OHSU scientists say low FOXP3 means fewer disease-fighting cells, but new drug may help multiple sclerosis

Oregon Health & Science University researchers have measured genetic changes reflecting a drop in the body's ability to suppress inflammatory cells that attack nerve fibers and promote progression of multiple sclerosis.

27 Jun 2005

New research raises the possibility that the risk of developing arsenic-related disease is not the same for everybody

Children with a particular variation in the CYT19 gene metabolize arsenic differently than adults with the same genetic variant, according to a new research report. The findings have important implications for the safety of drinking water worldwide and the use of arsenic as a cancer drug.

27 Jun 2005

Gene News and Research

Latest Gene News and Research

DNA imaging suggests where lung cancer genes may reside

Researchers use imaging to gain better understanding of cancerous cell behaviour

Researchers find enzyme vital for controlling the early stages of cell death

Scientists discover identifying markers for primitive blood-forming stem cells - simplifies cell identification

Protein that was thought to simply turn genes on and off now looks to be more like a cellular dimmer switch

Researchers have identified a highly specific pathway that causes inflammation in lung tissue

Map of gene control regions provides tool for understanding cells' different roles

Exercise helps find genetic regions linked to prediabetes

New clues about the location of genes potentially involved in the most common type of lung cancer

Study causes big shift in how we think about p53 gene

Researchers successfully treat laboratory model of a lysosomal storage disease called GM1

If you know how viruses get into cells, you know how to better design drugs to keep them out

Technique called phylogenetic footprinting reveals new gene regulation system

OHSU scientists say low FOXP3 means fewer disease-fighting cells, but new drug may help multiple sclerosis

New research raises the possibility that the risk of developing arsenic-related disease is not the same for everybody

Study challenges understanding of how messenger RNAs are translated into proteins

Study sheds new light on the molecular mechanisms underlying the development of chronic wounds

Expression profiles and functional analyses of Wnt-related genes in human joint disorders

Special genes enable some women to give birth over the age of 45

AAV2 has great potential to be developed as an anti-cancer agent

eBook: Using iPSCs models for human disease research and drug discovery eBook

Precision in every drop: Inside Hamilton’s syringe technology

Exploring the Future of Neuroscience Drug Discovery

Genomic conservation in Thailand's mangroves