Gene News and Research

Latest Gene News and Research

Innovative new cancer drug enters the first phase of clinical trials

An innovative drug with a new mechanism of action that may be effective against a range of cancers will enter the first phase of clinical trials, it was announced today (Monday) at Cancer Research UK's Senior Researchers Meeting.

24 May 2004

Scientists have genetically engineered a mouse with extraordinary resistance to bowel cancer

Scientists have genetically engineered a mouse with extraordinary resistance to bowel cancer, delegates at the Cancer Research UK senior researchers' conference in Harrogate will hear today.

24 May 2004

Researchers have identified the first gene linked to the productivity of the stem cells that produce sperm in mammals

Researchers have identified the first gene linked to the productivity of the stem cells that produce sperm in mammals. The discovery was made by applying the latest laboratory methods to a strain of mice restored from embryos frozen since the early 70s.

23 May 2004

Using gene therapy to fight rheumatoid arthritis

Guided by a similar principle, arthritis researchers at the University of Florida and Harvard University hope to use gene therapy to help joint cells pump out a harmless protein that parks in receptor sites, leaving a notorious inflammatory agent “circling the lot” and unable to cause pain, swelling and possible joint damage.

21 May 2004

Genome research sheds light on Bardet-Biedl syndrome

By comparing the genomes of an alga, a weed and humans, a team of researchers has identified a new gene behind Bardet-Biedl syndrome (BBS), a complex condition marked by learning disabilities, vision loss and obesity.

21 May 2004

Discovery and improvement of glyphosate tolerance gene

Verdia Inc., a wholly owned subsidiary of Maxygen, Inc. has announced today the publication in the journal Science of a study that describes the successful development of a novel glyphosate-resistant crop trait by scientists at Verdia and Pioneer Hi-Bred International, Inc., a wholly owned subsidiary of DuPont.

21 May 2004

Tumour suppressor gene family may be key to new colon cancer drugs

In the hunt for new cancer drug targets, scientists from the Johns Hopkins Kimmel Cancer Center and the Howard Hughes Medical Institute have discovered mutations in a family of genes linked to more than a quarter of colon cancers, as well as several other common cancers including breast and lung.

20 May 2004

Scientists believe that the dog genome holds a wealth of information that will benefit human health

Recently completed genetic analysis reveals that half of the more than 300 inherited canine disorders — including a number of cancers — resemble specific diseases of man; many scientists believe that the dog genome holds a wealth of information that will benefit human health.

20 May 2004

Protein that appears to play a key role in Alzheimer's disease

A protein that allows human cancer to resist multiple anticancer drugs also appears to play a key role in Alzheimer's disease, according to research conducted at Fox Chase Cancer Center. The protein, active in brain tissue, could be a target for new drugs to treat patients with Alzheimer's.

20 May 2004

A genetic variant (MTHFR C677T) puts half the population at increased risk of neural tube defects

Researchers in Ireland and the United States identified the genetic make-up (genotype) of 395 individuals born with neural tube defects (spina bifida or encephalocele) and 848 controls.

20 May 2004

Scientists have sped up a common jumping gene found in the human genome

Johns Hopkins scientists have transformed a common "jumping gene" found in the human genome into one that moves hundreds of times more often than normal in mouse and human cells.

20 May 2004

Scientists have taken the first steps towards producing a sustainable and pure source of the healthy fats found in oily fish

Eating such fish is encouraged as part of a healthy diet as their oils are rich in very long chain polyunsaturated fatty acids (VLCPUFAs). However, views on the health-promoting nature of VLCPUFAs have to be balanced against the marine pollution that can cause fish, and the oils extracted from them, to be contaminated with heavy metals and dioxins, and the fact that fish stocks are in global decline.

20 May 2004

New study of tumor genetics may help to treat patients with head and neck cancer

Head and neck tumors account for more than 40,000 new cancers annually in the United States. The most common of these is squamous cell carcinoma. Prognosis is based largely on location and size of the tumor, and if the cancer has spread, or metastasized, to lymph nodes and distant sites in the body.

19 May 2004

Closer to understanding the function of a protein linked to an inherited form of the movement disorder dystonia

The protein, torsinA, is defective in patients with DYT1 dystonia, an inherited condition that causes uncontrollable movements in the limbs and torso. Learning what torsinA does could be an important step toward developing a treatment for the disorder.

19 May 2004

Inactivating a protective molecule may help chemotherapy for leukemia but harm bone marrow

Inactivating a protective molecule in leukemic cells to make them more vulnerable to chemotherapy might also make healthy blood-forming cells more sensitive to the toxic effects of those same drugs.

19 May 2004

Benitec acquires Avocel to focus on rapid development of hepatitis C therapeutics

Benitec Ltd. today announced the acquisition of Avocel, Inc. of Sunnyvale, CA, a leading RNAi therapeutics company, and the establishment of its wholly-owned US subsidiary, Benitec, Inc. Through the acquisition, Benitec gains its first in-house advanced therapeutic development program using DNA-directed RNAi (ddRNAi) to target the Hepatitis C virus.

18 May 2004

Discovery of the gene for Cornelia de Lange syndrome

An international team of researchers has discovered the gene for Cornelia de Lange syndrome, a disabling, multisystem genetic disease that affects an estimated one in 10,000 children. The finding is expected to lead to a genetic test, enabling rapid and definitive diagnosis of the syndrome, as well as prenatal testing for families who already have one child with the disease.

17 May 2004

Inheriting the wrong version of a gene called CHEK2 doubles a woman's risk of developing breast cancer

Inheriting the wrong version of a gene called CHEK2 doubles a woman's risk of developing breast cancer, Cancer Research UK scientists confirm in a major new international study published in the June edition of the American Journal of Human Genetics.

17 May 2004

Want a new type of man? Maybe less brawn and more brains?

A new version of the human male is a distinct possibility, given the genetic erosion of the “junk” sex-determining chromosome that makes men male.

17 May 2004

Genetically engineered viruses may create new class of cancer therapies

A genetically engineered virus can selectively kill cancerous cells in the lung and colon while leaving healthy cells intact, according to new research published today in Cancer Research by William Wold and colleagues at Saint Louis University School of Medicine.

15 May 2004

Gene News and Research

Latest Gene News and Research

Innovative new cancer drug enters the first phase of clinical trials

Scientists have genetically engineered a mouse with extraordinary resistance to bowel cancer

Researchers have identified the first gene linked to the productivity of the stem cells that produce sperm in mammals

Using gene therapy to fight rheumatoid arthritis

Genome research sheds light on Bardet-Biedl syndrome

Discovery and improvement of glyphosate tolerance gene

Tumour suppressor gene family may be key to new colon cancer drugs

Scientists believe that the dog genome holds a wealth of information that will benefit human health

Protein that appears to play a key role in Alzheimer's disease

A genetic variant (MTHFR C677T) puts half the population at increased risk of neural tube defects

Scientists have sped up a common jumping gene found in the human genome

Scientists have taken the first steps towards producing a sustainable and pure source of the healthy fats found in oily fish

New study of tumor genetics may help to treat patients with head and neck cancer

Closer to understanding the function of a protein linked to an inherited form of the movement disorder dystonia

Inactivating a protective molecule may help chemotherapy for leukemia but harm bone marrow

Benitec acquires Avocel to focus on rapid development of hepatitis C therapeutics

Discovery of the gene for Cornelia de Lange syndrome

Inheriting the wrong version of a gene called CHEK2 doubles a woman's risk of developing breast cancer

Want a new type of man? Maybe less brawn and more brains?

Genetically engineered viruses may create new class of cancer therapies

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From Discovery Biology to ELRIG Chair

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