Gene News and Research

Latest Gene News and Research

Accumulation of genetic changes is not solely determined by natural selection

New data suggest that the accumulation of genetic changes is not solely determined by natural selection. A study by University of Chicago researchers contradicts conventional theory by showing that the percentage of mutations accepted in evolution is also strongly swayed by the speed at which new mutations arrive at a gene: the faster the speed of new mutations, the greater the percentage of those mutations accepted.

9 Jun 2005

Study of glial cells in the roundworm C. elegans may provide insight into a variety of human brain diseases

The key to understanding our brains may lie within a one-millimeter long worm, new research from Rockefeller University indicates. Reporting in the June issue of Developmental Cell, Shai Shaham, Ph.D., and graduate student Elliot Perens use the roundworm, C. elegans, to investigate the mysterious glial cell, which makes up 90 percent of the human brain and, when it malfunctions, can contribute to diseases like Parkinson's disease and schizophrenia.

9 Jun 2005

New study shows tiny RNAs intimately associated with cancer

In discoveries that may open a new chapter in understanding and diagnosing cancer, Howard Hughes Medical Institute (HHMI) investigators and their colleagues have established that tiny microRNAs provide a novel genetic route to the initiation of some forms of cancer.

9 Jun 2005

New understanding of microRNAs

Ribonucleic acid, or RNA, has long been thought to be important only to translate a gene's DNA into the proteins that are cells' workhorses. But new evidence shows that tiny bits of RNA not used to make proteins actually play central roles in normal biology and in the development of cancers.

8 Jun 2005

New bioinformatics technique for systematically analyzing key regions in DNA that help control gene activity

Scientists at Lawrence Livermore National Laboratory (LLNL) and the Linnaeus Centre for Bioinformatics (LCB) at Uppsala University in Sweden have developed a new bioinformatics technique for systematically analyzing key regions in DNA that help control gene activity.

8 Jun 2005

Diversity of HLA genotypes in humans is shaped to a significant degree by pathogens

The great physical diversity that evolution has forged in human beings is in evidence wherever we look, but the genes exhibiting the greatest diversity at the DNA level happen to function in a wholly invisible process: immunity. Genes encoding the Human Leukocyte Antigen (HLA) proteins are among the most diverse in the human genome, and scientists have proposed a number of hypotheses to explain why.

6 Jun 2005

New dopamine transporter gene findings may be relevant for substance abuse, tobacco smoking, and ADHD

Confirming findings in a previous study, Yale researchers observed an altered availability of the dopamine transporter in healthy persons with a genetic variation linked to substance abuse and attention deficit hyperactivity disorder (ADHD).

6 Jun 2005

Gene therapy for arthritis is both feasible and safe

Gene therapy for arthritis and other non-terminal, debilitating conditions and diseases is both feasible and safe, report researchers who conducted the world's first such test on the approach in patients with advanced rheumatoid arthritis.

6 Jun 2005

Statisticians learn how to analyze huge quantities of genetic data

In a conceptual breakthrough, a team of researchers led by statisticians at the Harvard School of Public Health (HSPH) has figured out how to analyze huge quantities of genetic data, surpassing the capabilities of traditional techniques and speeding the quest for understanding the genetic basis of complex diseases such as asthma and diabetes.

6 Jun 2005

Researchers successfully image delivery and gene expression of DNA nanoparticles into lungs of CF mice

Researchers at the American Society of Gene Therapy Meeting in St. Louis announced that by using imaging technologies, they are able to successfully trace the delivery of DNA nanoparticles and the extent of gene transfer in the lungs of cystic fibrosis (CF) animals.

6 Jun 2005

Gene linked to lower breast cancer risk

In a presentation at the 2nd ESMO Scientific & Educational Conference (ESEC) in Budapest, Hungary, Dr. Uwe Langsenlehner and colleagues from Medical University Graz in Austria showed that a specific genetic variation in a cytokine gene is associated with lower breast cancer risk.

6 Jun 2005

Computer simulation helps understand DNA transcription process

New York University chemists have employed a computer simulation whose results have enhanced scientific understanding of the DNA transcription process. The study, funded by the National Institutes of Health, appears in the June 7 issue of the Proceedings of the National Academy of Sciences.

5 Jun 2005

Discovery will lead to more effective treatments for pulmonary arterial hypertension

A University of Alberta research team has discovered important new information they hope will lead to more effective treatments for pulmonary arterial hypertension (PAH)--a deadly form of high blood pressure in the pulmonary arteries caused by uncontrolled cell growth.

5 Jun 2005

Gene research may help explain how adorable children become surly teenagers

University of Utah researchers showed that a fruit fly gene is crucial for determining when juveniles begin to mature into adults, and how the transformation initially proceeds. Understanding this process in humans may help explain how adorable children become surly teenagers.

3 Jun 2005

Introgen wins European patent decision on p53 gene therapeutic

Introgen Therapeutics has announced that it was successful in winning the decision regarding its opposition of European Patent 0 390 323 before the European Patent Office (EPO) in which all claims directed to therapeutic applications of the p53 gene, the active component of Introgen's Advexin molecular therapy, were finally revoked by the EPO's Technical Board of Appeals.

3 Jun 2005

New understanding of jet lag

A new study demonstrates that the brain’s central timekeeper - the biological clock that regulates waking and sleeping cycles - has two parts that fall out of synchrony during light schedule shifts of six hours, the time it takes to fly across the Atlantic.

3 Jun 2005

Research shows how a virus uses the gene silencing machinery for its own infectious purposes

In the latest version of the hide-and-seek game between pathogens and the hosts they infect, researchers have found that a virus appears to cloak itself with a recently discovered gene silencing device to evade detection and destruction by immune cells.

3 Jun 2005

Role of toxins in inherited disease

A disease you are suffering today could be a result of your great-grandmother being exposed to an environmental toxin during pregnancy.

3 Jun 2005

Lactose intolerance linked to ancestral environment

Got milk? Many people couldn't care less because they can't digest it. A new Cornell University study finds that it is primarily people whose ancestors came from places where dairy herds could be raised safely and economically, such as in Europe, who have developed the ability to digest milk.

1 Jun 2005

Genetic variation alters response to anti-clotting drug warfarin

Millions of people take the anticoagulant drug warfarin to prevent harmful clotting after a heart attack, stroke, or major surgery. But the proper dose of warfarin can vary greatly and can be hard to predict.

1 Jun 2005

Gene News and Research

Latest Gene News and Research

Accumulation of genetic changes is not solely determined by natural selection

Study of glial cells in the roundworm C. elegans may provide insight into a variety of human brain diseases

New study shows tiny RNAs intimately associated with cancer

New understanding of microRNAs

New bioinformatics technique for systematically analyzing key regions in DNA that help control gene activity

Diversity of HLA genotypes in humans is shaped to a significant degree by pathogens

New dopamine transporter gene findings may be relevant for substance abuse, tobacco smoking, and ADHD

Gene therapy for arthritis is both feasible and safe

Statisticians learn how to analyze huge quantities of genetic data

Researchers successfully image delivery and gene expression of DNA nanoparticles into lungs of CF mice

Gene linked to lower breast cancer risk

Computer simulation helps understand DNA transcription process

Discovery will lead to more effective treatments for pulmonary arterial hypertension

Gene research may help explain how adorable children become surly teenagers

Introgen wins European patent decision on p53 gene therapeutic

New understanding of jet lag

Research shows how a virus uses the gene silencing machinery for its own infectious purposes

Role of toxins in inherited disease

Lactose intolerance linked to ancestral environment

Genetic variation alters response to anti-clotting drug warfarin

eBook: Using iPSCs models for human disease research and drug discovery eBook

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Exploring the Future of Neuroscience Drug Discovery

Genomic conservation in Thailand's mangroves