Gene News and Research

Latest Gene News and Research

The critical role of PGK1 in Parkinson's disease

An enzyme called PGK1 has an unexpectedly critical role in the production of chemical energy in brain cells, according to a preclinical study led by researchers at Weill Cornell Medicine. The investigators found that boosting its activity may help the brain resist the energy deficits that can lead to Parkinson's disease.

21 Aug 2024

New discovery reveals how DNA regulates inheritance of disease mutations

University of Queensland researchers have discovered a mechanism in DNA that regulates how disease-causing mutations are inherited.

21 Aug 2024

Protein encoded by the ASPN gene plays a protective role in pulmonary arterial hypertension

A new study from researchers with UCLA Health and collaborating organizations has found that asporin, a protein encoded by the ASPN gene, plays a protective role in pulmonary arterial hypertension (PAH).

21 Aug 2024

Targeted therapy slows endometrial cancer growth in mice models

There may be a way to slow the growth of endometrial cancer through targeted cancer cell therapy, according to new research from the University of Missouri School of Medicine.

21 Aug 2024

The role of the gut microbiota in multiple sclerosis: A scientometric analysis reveals key research trends

Researchers examine the relationship between gut microbiota and multiple sclerosis.

21 Aug 2024

Study finds potential for antidiabetic drugs to modify osteoarthritis risk

Whether antidiabetic medications could potentially be used as disease-modifying osteoarthritis drugs or DMOADs for the therapeutic management of osteoarthritis.

21 Aug 2024

Spatial transcriptomics unlocks malaria's liver stage secrets

For the malaria parasite to reach the blood of its human host, it must first enter the liver, where only a small number of parasites differentiate and replicate for upwards of seven days, making it a bottleneck in the parasite's lifecycle. This bottleneck makes the liver stage an optimal target for effective and long-lasting vaccines against the disease. Using Spatial Transcriptomics and single-cell RNA-sequencing technologies, researchers at Stockholm University have for the first time managed to create a spatio-temporal map of malaria infection in the mouse liver. A study that was recently published in Nature Communications.

21 Aug 2024

Exploring gene silencing mechanisms for improved RNAi therapeutics

RNA interference (RNAi) therapeutics have garnered significant attention in clinical research due to their potential for treating various diseases, including genetic disorders, viral infections and cancer.

20 Aug 2024

UofL researchers receive $3.6 million to study the role of arsenic exposure in causing health problems

University of Louisville researchers have received $3.6 million in new grant funding to study the role of arsenic exposure in causing cancer and other major health concerns.

20 Aug 2024

Precision medicine enhances prostate cancer treatment with genetic profiling

Men with metastatic castration-resistant prostate cancer should be treated primarily with second-generation hormone drugs, which offer better treatment response and longer life expectancy than chemotherapy.

20 Aug 2024

How persistent organic pollutants affect gut health: findings on metabolic disruptions and microbiota changes

Early life exposure to potent AHR agonists on gut microbiota and its potential effects on metabolic health later in life.

20 Aug 2024

Exploring the health benefits and production challenges of alternative proteins

Researchers review the health benefits of alternative protein sources and the challenges associated with their production.

20 Aug 2024

How the MIND diet may protect against dementia

Researchers utilize transcriptomic data to examine the protective effects of the MIND diet in reducing the risk of dementia and slowing cognitive decline.

20 Aug 2024

Researchers reveal impact of genetic ancestry on breast cancer risk and cell diversity

Researchers map the diverse cell types present in healthy breast tissue to elucidate the role of genetic ancestry in breast cancer risk.

20 Aug 2024

Study reveals genetic link between Alzheimer's disease, lipid metabolism, and coronary artery disease

The genetic overlap between Alzheimer's disease (AD) (a neurodegenerative disorder causing memory loss and cognitive decline), lipid profiles, and coronary artery disease (CAD).

20 Aug 2024

Expanding the TTN mutation spectrum for dilated cardiomyopathy diagnosis

Announcing a new article publication for Cardiovascular Innovations and Applications journal. Dilated cardiomyopathy (DCM), a severe heart disease, is the leading cause of heart failure and sudden cardiac death worldwide.

19 Aug 2024

Breakthrough research unveils retroelement-based aging biomarkers

Researchers at Weill Cornell Medicine and the epigenetics company TruDiagnostic have uncovered DNA markers associated with retroelements, remnants of ancient viral genetic material, in our genes that act as highly accurate epigenetic clocks predicting chronological age.

19 Aug 2024

Researchers identify possible candidates for multipotent stem cells in the sea anemone

The sea anemone Nematostella vectensis is potentially immortal. Using molecular genetic methods, developmental biologists led by Ulrich Technau from the University of Vienna have now identified possible candidates for multipotent stem cells in the sea anemone for the first time.

19 Aug 2024

New Springer textbook provides a comprehensive overview of aging science

A new textbook provides an overview on the present understanding of aging - from the basic biology of aging to age-related diseases and to the role of lifestyle and the environment.

19 Aug 2024

APOE ε4 carrier status increases the long-term cognitive decline risk associated with herpes zoster

The long-term subjective cognitive decline risk associated with Herpes zoster infections.

19 Aug 2024

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Gene News and Research

Latest Gene News and Research

The critical role of PGK1 in Parkinson's disease

New discovery reveals how DNA regulates inheritance of disease mutations

Protein encoded by the ASPN gene plays a protective role in pulmonary arterial hypertension

Targeted therapy slows endometrial cancer growth in mice models

The role of the gut microbiota in multiple sclerosis: A scientometric analysis reveals key research trends

Study finds potential for antidiabetic drugs to modify osteoarthritis risk

Spatial transcriptomics unlocks malaria's liver stage secrets

Exploring gene silencing mechanisms for improved RNAi therapeutics

UofL researchers receive $3.6 million to study the role of arsenic exposure in causing health problems

Precision medicine enhances prostate cancer treatment with genetic profiling

How persistent organic pollutants affect gut health: findings on metabolic disruptions and microbiota changes

Exploring the health benefits and production challenges of alternative proteins

How the MIND diet may protect against dementia

Researchers reveal impact of genetic ancestry on breast cancer risk and cell diversity

Study reveals genetic link between Alzheimer's disease, lipid metabolism, and coronary artery disease

Expanding the TTN mutation spectrum for dilated cardiomyopathy diagnosis

Breakthrough research unveils retroelement-based aging biomarkers

Researchers identify possible candidates for multipotent stem cells in the sea anemone

New Springer textbook provides a comprehensive overview of aging science

APOE ε4 carrier status increases the long-term cognitive decline risk associated with herpes zoster

eBook: Using iPSCs models for human disease research and drug discovery eBook

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production